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In multi-view medical diagnosis, deep learning-based models often fuse information from different imaging perspectives to improve diagnostic performance. However, existing approaches are prone to overfitting and rely heavily on…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Jingyu Guo , Christos Matsoukas , Fredrik Strand , Kevin Smith

This paper proposes a non-interactive end-to-end solution for secure fusion and matching of biometric templates using fully homomorphic encryption (FHE). Given a pair of encrypted feature vectors, we perform the following ciphertext…

计算机视觉与模式识别 · 计算机科学 2022-08-16 Luke Sperling , Nalini Ratha , Arun Ross , Vishnu Naresh Boddeti

With the rapid development of deep learning and computer vision technologies, medical image segmentation plays a crucial role in the early diagnosis of breast cancer. However, due to the characteristics of breast ultrasound images, such as…

计算机视觉与模式识别 · 计算机科学 2024-12-24 Jiajun Ding , Beiyao Zhu , Wenjie Wang , Shurong Zhang , Dian Zhua , Zhao Liua

Identification of nearly all proteins in a system using data-dependent acquisition (DDA) mass spectrometry has become routine for simple organisms, such as bacteria and yeast. Still, quantification of the identified proteins may be a…

定量方法 · 定量生物学 2019-01-21 Jesse G. Meyer

News text classification is a crucial task in natural language processing, essential for organizing and filtering the massive volume of digital content. Traditional methods typically rely on statistical features like term frequencies or…

计算与语言 · 计算机科学 2025-11-24 Mohammad Zare

One of the fundamental tasks in understanding genomics is the problem of predicting Transcription Factor Binding Sites (TFBSs). With more than hundreds of Transcription Factors (TFs) as labels, genomic-sequence based TFBS prediction is a…

机器学习 · 计算机科学 2017-11-13 Jack Lanchantin , Arshdeep Sekhon , Ritambhara Singh , Yanjun Qi

With the advent of large pre-trained transformer models, fine-tuning these models for various downstream tasks is a critical problem. Paucity of training data, the existence of data silos, and stringent privacy constraints exacerbate this…

计算机视觉与模式识别 · 计算机科学 2024-07-17 Naif Alkhunaizi , Faris Almalik , Rouqaiah Al-Refai , Muzammal Naseer , Karthik Nandakumar

Deep neural networks, particularly Transformers, have been widely adopted for predicting the functional properties of proteins. In this work, we focus on exploring whether Protein Transformers can capture biological intelligence among…

机器学习 · 计算机科学 2025-06-10 Fudong Lin , Wanrou Du , Jinchan Liu , Tarikul Milon , Shelby Meche , Wu Xu , Xiaoqi Qin , Xu Yuan

The problem of motif detection can be formulated as the construction of a discriminant function to separate sequences of a specific pattern from background. In computational biology, motif detection is used to predict DNA binding sites of a…

基因组学 · 定量生物学 2010-12-10 Qing Zhou

Most modern multiple object tracking (MOT) systems follow the tracking-by-detection paradigm, consisting of a detector followed by a method for associating detections into tracks. There is a long history in tracking of combining motion and…

计算机视觉与模式识别 · 计算机科学 2021-06-08 Mohamed Chaabane , Peter Zhang , J. Ross Beveridge , Stephen O'Hara

This paper presents a new face identification system based on Graph Matching Technique on SIFT features extracted from face images. Although SIFT features have been successfully used for general object detection and recognition, only…

计算机视觉与模式识别 · 计算机科学 2010-02-03 Dakshina Ranjan Kisku , Ajita Rattani , Enrico Grosso , Massimo Tistarelli

Face anti-spoofing (FAS) and adversarial detection (FAD) have been regarded as critical technologies to ensure the safety of face recognition systems. However, due to limited practicality, complex deployment, and the additional…

计算机视觉与模式识别 · 计算机科学 2024-08-28 Jiawei Chen , Xiao Yang , Yinpeng Dong , Hang Su , Zhaoxia Yin

When no arterial input function is available, quantification of dynamic PET images requires a previous step devoted to the extraction of a reference time-activity curve (TAC). Factor analysis is often applied for this purpose. This paper…

图像与视频处理 · 电气工程与系统科学 2020-11-23 Yanna Cruz Cavalcanti , Thomas Oberlin , Vinicius Ferraris , Nicolas Dobigeon , Maria Ribeiro , Clovis Tauber

Frequent Itemsets (FIs) mining is a fundamental primitive in data mining. It requires to identify all itemsets appearing in at least a fraction $\theta$ of a transactional dataset $\mathcal{D}$. Often though, the ultimate goal of mining…

机器学习 · 计算机科学 2014-01-23 Matteo Riondato , Fabio Vandin

We propose a novel approach to detect the binding between proteins making use of the anomalous diffraction of natively present heavy elements inside the molecule 3D structure. In particular, we suggest considering sulfur atoms contained in…

Index is an important component in database systems. Learned indexes have been shown to outperform traditional tree-based index structures for fixed-sized integer or floating point keys. However, the application of the learned solution to…

数据库 · 计算机科学 2024-07-17 Yifan Yang , Shimin Chen

Accurate protein function prediction requires integrating heterogeneous intrinsic signals (e.g., sequence and structure) with noisy extrinsic contexts (e.g., protein-protein interactions and GO term annotations). However, two key challenges…

机器学习 · 计算机科学 2025-10-28 Runjie Zheng , Zhen Wang , Anjie Qiao , Jiancong Xie , Jiahua Rao , Yuedong Yang

Protein structure generative models have seen a recent surge of interest, but meaningfully evaluating them computationally is an active area of research. While current metrics have driven useful progress, they do not capture how well models…

生物大分子 · 定量生物学 2025-07-25 Felix Faltings , Hannes Stark , Tommi Jaakkola , Regina Barzilay

Peptide identification in mass spectrometry-based proteomics is crucial for understanding protein function and dynamics. Traditional database search methods, though widely used, rely on heuristic scoring functions and statistical…

定量方法 · 定量生物学 2024-05-13 Yonghan Yu , Ming Li

Federated Instruction Tuning (FIT) has shown the ability to achieve collaborative model instruction tuning among massive data owners without sharing private data. However, it still faces two key challenges, i.e., data and resource…

机器学习 · 计算机科学 2024-02-28 Pengyu Zhang , Yingbo Zhou , Ming Hu , Junxian Feng , Jiawen Weng , Mingsong Chen