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Current unsupervised anomaly detection approaches perform well on public datasets but struggle with specific anomaly types due to the domain gap between pre-trained feature extractors and target-specific domains. To tackle this issue, this…

计算机视觉与模式识别 · 计算机科学 2024-07-02 Yun Liang , Zhiguang Hu , Junjie Huang , Donglin Di , Anyang Su , Lei Fan

We consider unsupervised cell nuclei segmentation in this paper. Exploiting the recently-proposed unpaired image-to-image translation between cell nuclei images and randomly synthetic masks, existing approaches, e.g., CycleGAN, have…

图像与视频处理 · 电气工程与系统科学 2022-03-11 Kai Yao , Kaizhu Huang , Jie Sun , Curran Jude

Early detection of newly emerging diseases, lesion severity assessment, differentiation of medical conditions and automated screening are examples for the wide applicability and importance of anomaly detection (AD) and unsupervised…

计算机视觉与模式识别 · 计算机科学 2025-09-17 Branko Mitic , Philipp Seeböck , Helmut Prosch , Georg Langs

This paper proposes a novel automatic classification framework for the recognition of five types of white blood cells. Segmenting complete white blood cells from blood smears images and extracting advantageous features from them remain…

计算机视觉与模式识别 · 计算机科学 2020-09-07 Na Dong , Meng-die Zhai , Jian-fang Chang , Chun-ho Wu

Acne detection is crucial for interpretative diagnosis and precise treatment of skin disease. The arbitrary boundary and small size of acne lesions lead to a significant number of poor-quality proposals in two-stage detection. In this…

计算机视觉与模式识别 · 计算机科学 2022-07-11 Jianwei Zhang , Lei Zhang , Junyou Wang , Xin Wei , Jiaqi Li , Xian Jiang , Dan Du

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

音频与语音处理 · 电气工程与系统科学 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

Active Learning (AL) has the potential to solve a major problem of digital pathology: the efficient acquisition of labeled data for machine learning algorithms. However, existing AL methods often struggle in realistic settings with…

计算机视觉与模式识别 · 计算机科学 2024-04-09 Arne Schmidt , Pablo Morales-Álvarez , Lee A. D. Cooper , Lee A. Newberg , Andinet Enquobahrie , Aggelos K. Katsaggelos , Rafael Molina

Training robust deep learning (DL) systems for medical image classification or segmentation is challenging due to limited images covering different disease types and severity. We propose an active learning (AL) framework to select most…

计算机视觉与模式识别 · 计算机科学 2019-10-23 Dwarikanath Mahapatra , Behzad Bozorgtabar , Jean-Philippe Thiran , Mauricio Reyes

Accurate assessment of human epidermal growth factor receptor 2 (HER2) expression is critical for breast cancer diagnosis, prognosis, and therapy selection; yet, most existing digital HER2 scoring methods rely on bulky and expensive optical…

医学物理 · 物理学 2026-01-27 Che-Yung Shen , Xilin Yang , Yuzhu Li , Leon Lenk , Aydogan Ozcan

Self-supervised contrastive learning is an effective approach for addressing the challenge of limited labelled data. This study builds upon the previously established two-stage patch-level, multi-label classification method for…

计算机视觉与模式识别 · 计算机科学 2026-02-09 Salma Haidar , José Oramas

This paper addresses the problem of quantifying biomarkers in multi-stained tissues, based on color and spatial information. A deep learning based method that can automatically localize and quantify the cells expressing biomarker(s) in a…

组织与器官 · 定量生物学 2017-01-02 Fahime Sheikhzadeh , Martial Guillaud , Rabab K. Ward

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

图像与视频处理 · 电气工程与系统科学 2021-08-31 Sota Kato , Kazuhiro Hotta

The evaluation of the Human Epidermal growth factor Receptor-2 (HER2) expression is an important prognostic biomarker for breast cancer treatment selection. However, HER2 scoring has notoriously high interobserver variability due to stain…

图像与视频处理 · 电气工程与系统科学 2022-11-18 Manh Dan Pham , Cyprien Tilmant , Stéphanie Petit , Isabelle Salmon , Saima Ben Hadj , Rutger H. J. Fick

Anomaly detection is a critical task in computer vision with profound implications for medical imaging, where identifying pathologies early can directly impact patient outcomes. While recent unsupervised anomaly detection approaches show…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Le Dong , Qinzhong Tan , Chunlei Li , Jingliang Hu , Yilei Shi , Weisheng Dong , Xiao Xiang Zhu , Lichao Mou

Estimating over-amplification of human epidermal growth factor receptor 2 (HER2) on invasive breast cancer (BC) is regarded as a significant predictive and prognostic marker. We propose a novel deep reinforcement learning (DRL) based model…

计算机视觉与模式识别 · 计算机科学 2019-03-27 Talha Qaiser , Nasir M. Rajpoot

Heterogeneous face recognition between color image and depth image is a much desired capacity for real world applications where shape information is looked upon as merely involved in gallery. In this paper, we propose a cross-modal deep…

计算机视觉与模式识别 · 计算机科学 2017-09-15 Wuming Zhang , Zhixin Shu , Dimitris Samaras , Liming Chen

The era of digital pathology has advanced histopathological examinations, making automated image analysis essential in clinical practice. This study evaluates the classification performance of machine learning and deep learning models on…

计算机视觉与模式识别 · 计算机科学 2026-04-29 Ifeanyi Ezuma , Ugochukwu Ugwu

Histopathological cancer diagnostics has become more complex, and the increasing number of biopsies is a challenge for most pathology laboratories. Thus, development of automatic methods for evaluation of histopathological cancer sections…

图像与视频处理 · 电气工程与系统科学 2021-12-08 André Pedersen , Erik Smistad , Tor V. Rise , Vibeke G. Dale , Henrik S. Pettersen , Tor-Arne S. Nordmo , David Bouget , Ingerid Reinertsen , Marit Valla

Histopathological imaging is vital for cancer research and clinical practice, with multiplexed Immunofluorescence (MxIF) and Hematoxylin and Eosin (H&E) providing complementary insights. However, aligning different stains at the cell level…

图像与视频处理 · 电气工程与系统科学 2024-10-02 Jun Jiang , Raymond Moore , Brenna Novotny , Leo Liu , Zachary Fogarty , Ray Guo , Markovic Svetomir , Chen Wang

Classification is one of the core problems in Computer-Aided Diagnosis (CAD), targeting for early cancer detection using 3D medical imaging interpretation. High detection sensitivity with desirably low false positive (FP) rate is critical…

计算机视觉与模式识别 · 计算机科学 2014-05-20 Meizhu Liu , Le Lu , Xiaojing Ye , Shipeng Yu
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