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This paper presents an intracellular feedback control strategy, to regulate the gene expression process dynamics. For this purpose, two types of genetic circuits are designed in order to compare concentrations of the input transcription…

系统与控制 · 计算机科学 2016-06-15 Jafar Kazemi , Sadjad Ozgoli

This paper presents a data-driven model for Linear Time-Invariant (LTI) stochastic systems by sampling from the conditional probability distribution of future outputs given past input-outputs and future inputs. It operates in a fully…

最优化与控制 · 数学 2025-11-27 Jiayun Li , Yilin Mo

Contrastive learning produces coherent semantic feature embeddings by encouraging positive samples to cluster closely while separating negative samples. However, existing contrastive learning methods lack principled guarantees on coverage…

机器学习 · 计算机科学 2026-03-30 Yahya Alkhatib , Wee Peng Tay

Contrastive dimension reduction methods have been developed for case-control study data to identify variation that is enriched in the foreground (case) data X relative to the background (control) data Y. Here, we develop contrastive…

统计方法学 · 统计学 2024-01-09 Boyang Zhang , Sarah Nyquist , Andrew Jones , Barbara E. Engelhardt , Didong Li

Predictive coding is a promising theoretical framework in neuroscience for understanding information transmission and perception. It posits that the brain perceives the external world through internal models and updates these models under…

神经元与认知 · 定量生物学 2022-09-07 Zhen-Ye Huang , Xin-Yi Fan , Jianwen Zhou , Hai-Jun Zhou

The latency of visual responses generally decreases as contrast increases. Recording in the lateral geniculate nucleus (LGN), we find that response latency increases with increasing contrast in ON cells for some visual stimuli. We propose…

神经元与认知 · 定量生物学 2012-10-01 Kate S. Gaudry , Pamela Reinagel

Electrocardiogram (ECG) acquisition requires an automated system and analysis pipeline for understanding specific rhythm irregularities. Deep neural networks have become a popular technique for tracing ECG signals, outperforming human…

Generating images from word descriptions is a challenging task. Generative adversarial networks(GANs) are shown to be able to generate realistic images of real-life objects. In this paper, we propose a new neural network architecture of…

计算机视觉与模式识别 · 计算机科学 2018-06-11 Xu Ouyang , Xi Zhang , Di Ma , Gady Agam

We study three different lattice models in which two species of diffusing particles are driven in opposite directions by an electric field. We focus on dynamical phase transitions that involve phase separation into domains that may be…

统计力学 · 物理学 2022-09-15 Honghao Yu , Kristian Thijssen , Robert L. Jack

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

种群与进化 · 定量生物学 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

A class of systems is considered, where immobile species associated to distinct patches, the nodes of a network, interact both locally and at a long-range, as specified by an (interaction) adjacency matrix. Non local interactions are…

斑图形成与孤子 · 物理学 2020-06-30 Giulia Cencetti , Federico Battiston , Timoteo Carletti , Duccio Fanelli

In recent years, Generative Adversarial Networks (GANs) have seen significant advancements, leading to their widespread adoption across various fields. The original GAN architecture enables the generation of images without any specific…

机器学习 · 计算机科学 2024-09-04 Anis Bourou , Valérie Mezger , Auguste Genovesio

Conditional Generative Adversarial Networks~(CGAN) are a recent and popular method for generating samples from a probability distribution conditioned on latent information. The latent information often comes in the form of a discrete label…

机器学习 · 统计学 2020-03-19 Edoardo Lisi , Mohammad Malekzadeh , Hamed Haddadi , F. Din-Houn Lau , Seth Flaxman

Turing patterns can be observed in reaction-diffusion systems where chemical species have different diffusion constants. In recent years, several studies investigated the effects of noise on Turing patterns and showed that the parameter…

计算物理 · 物理学 2013-10-30 Yang Cao , Radek Erban

We target modeling latent dynamics in high-dimension marked event sequences without any prior knowledge about marker relations. Such problem has been rarely studied by previous works which would have fundamental difficulty to handle the…

机器学习 · 计算机科学 2019-10-29 Qitian Wu , Zixuan Zhang , Xiaofeng Gao , Junchi Yan , Guihai Chen

A system of coupled oscillators on an arbitrary graph is locally driven by the tendency to mutual synchronization between nearby oscillators, but can and often exhibit nonlinear behavior on the whole graph. Understanding such nonlinear…

动力系统 · 数学 2023-11-28 Agam Goyal , Zhaoxing Wu , Richard P. Yim , Binhao Chen , Zihong Xu , Hanbaek Lyu

Generative adversarial networks (GANs) have shown remarkable success in generation of unstructured data, such as, natural images. However, discovery and separation of modes in the generated space, essential for several tasks beyond naive…

计算机视觉与模式识别 · 计算机科学 2019-03-26 Deepak Mishra , Prathosh A. P. , Aravind Jayendran , Varun Srivastava , Santanu Chaudhury

A novel mechanism for cell differentiation is proposed, based on the dynamic clustering in a globally coupled chaotic system. A simple model with metabolic reaction, active transport of chemicals from media, and cell division is found to…

adap-org · 物理学 2009-10-22 Kunihiko Kaneko , Tetsuya Yomo

Expressive text-to-speech systems have undergone significant advancements owing to prosody modeling, but conventional methods can still be improved. Traditional approaches have relied on the autoregressive method to predict the quantized…

声音 · 计算机科学 2025-01-22 Hyung-Seok Oh , Sang-Hoon Lee , Seong-Whan Lee

Adversarial learning helps generative models translate MRI from source to target sequence when lacking paired samples. However, implementing MRI synthesis with adversarial learning in clinical settings is challenging due to training…

图像与视频处理 · 电气工程与系统科学 2024-07-04 Luyi Han , Tao Tan , Tianyu Zhang , Xin Wang , Yuan Gao , Chunyao Lu , Xinglong Liang , Haoran Dou , Yunzhi Huang , Ritse Mann