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The high motility of synaptic weights raises the question of how the brain can retain its functionality in the face of constant synaptic remodeling. Here we used the whisker system of rats and mice to study the interplay between synaptic…

生物物理 · 物理学 2024-02-01 Nimrod Sherf , Maoz Shamir

The behavior of living systems is based on the experience they gained through their interactions with the environment [1]. This experience is stored in the complex biochemical networks of cells and organisms to provide a relationship…

软凝聚态物质 · 物理学 2022-02-14 Santiago Muiños-Landin , Keyan Ghazi-Zahedi , Frank Cichos

Most neurons in peripheral sensory pathways initially respond vigorously when a preferred stimulus is presented, but adapt as stimulation continues. It is unclear how this phenomenon affects stimulus representation in the later stages of…

神经元与认知 · 定量生物学 2012-10-29 Farzad Farkhooi , Anja Froese , Eilif Muller , Randolf Menzel , Martin P. Nawrot

Behavioral control over stressful stimuli induces resilience to future conditions when control is lacking. The medial prefrontal cortex(mPFC) is a critically important brain region required for plasticity of stress resilience. We found that…

神经元与认知 · 定量生物学 2012-04-06 Juan A. Varela , Jungang Wang , Andrew L. Varnell , Donald C. Cooper

In this Letter, we study the collective behaviour of a large number of self-propelled microswimmers immersed in a fluid. Using unprecedently large-scale lattice Boltzmann simulations, we reproduce the transition to bacterial turbulence. We…

软凝聚态物质 · 物理学 2017-07-17 Joakim Stenhammar , Cesare Nardini , Rupert W. Nash , Davide Marenduzzo , Alexander Morozov

Time perception is essential for task switching, and in the mammalian brain appears alongside other processes. Memristors are electronic components used as synapses and as models for neurons. The d.c. response of memristors can be…

机器人学 · 计算机科学 2014-02-18 Ella Gale , Ben de Lacy Costello , Andrew Adamatzky

The habitat of microorganisms is typically complex and viscoelastic. A natural question arises: Do polymers in a suspension of active swimmers enhance chaotic motion or promote orientational order? We address this issue by performing…

软凝聚态物质 · 物理学 2025-12-23 Yuan Zhou , Qingzhi Zou , Ignacio Pagonabarraga , Kaihuan Zhang , Kai Qi

We present a detailed numerical study of a microscopic artificial swimmer realized recently by Dreyfus et al. in experiments [R. Dreyfus et al., Nature 437, 862 (2005)]. It consists of an elastic filament composed of superparamagnetic…

软凝聚态物质 · 物理学 2008-05-21 Erik M. Gauger , Holger Stark

Fish rheotaxis, or alignment into flow currents, results from intertwined sensory, neural and actuation mechanisms, all coupled with hydrodynamics to produce a behavior that is critical for upstream migration and position holding in…

流体动力学 · 物理学 2016-04-20 Brendan Colvert , Eva Kanso

We report the simultaneous characterization of time- and force-dependent mechanical properties of adherent cells in the physiologically relevant regime of large forces. We used magnetic tweezers to apply forces to magnetic beads bound to…

生物物理 · 物理学 2010-02-02 Philip Kollmannsberger , Claudia T. Mierke , Ben Fabry

The preB\"otzinger Complex, the mammalian inspiratory rhythm generator, encodes inspiratory time as motor pattern. Spike synchronization throughout this sparsely connected network generates inspiratory bursts albeit with variable latencies…

神经元与认知 · 定量生物学 2020-12-24 Valentin M. Slepukhin , Sufyan Ashhad , Jack L. Feldman , Alex J. Levine

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

神经元与认知 · 定量生物学 2022-08-15 Ganchao Wei , Ian H. Stevenson

Rectilinear crawling locomotion is a primitive and common mode of locomotion in slender, soft-bodied animals. It requires coordinated contractions that propagate along a body that interacts frictionally with its environment. We propose a…

生物物理 · 物理学 2021-08-31 Shruti Mishra , Wim M. van Rees , L. Mahadevan

We study the motion of a microscopic swimmer composed of a semiflexible polymer anchored at the surface of a magnetic sphere using hydrodynamic simulations and scaling arguments. The swimmer is driven by a rotating magnetic field, and…

软凝聚态物质 · 物理学 2007-05-23 A. Alexander-Katz

Similar activity patterns may arise from model neural networks with distinct coupling properties and individual unit dynamics. These similar patterns may, however, respond differently to parameter variations and, specifically, to tuning of…

神经元与认知 · 定量生物学 2023-06-16 Zhuojun Yu , Jonathan E. Rubin , Peter J. Thomas

Various classes of neurons alternate between high-frequency discharges and silent intervals. This phenomenon is called burst firing. To analyze burst activity in an insect system, grasshopper auditory receptor neurons were recorded in vivo…

神经元与认知 · 定量生物学 2008-07-17 Hugo G. Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo

Self-propelled microorganisms, such as unicellular algae or bacteria, swim along their director relative to the fluid velocity. Under a steady shear flow the director rotates in close orbit, a periodic structure that is preserved under an…

软凝聚态物质 · 物理学 2015-06-11 Francisca Guzman-Lastra , Rodrigo Soto

The genetic regulatory network (GRN) plays a key role in controlling the response of the cell to changes in the environment. Although the structure of GRNs has been the subject of many studies, their large scale structure in the light of…

分子网络 · 定量生物学 2018-11-21 Santhust Kumar , Saurabh Mahajan , Sanjay Jain

Cyborg in the brain-machine interface field has attracted more attention in recent years. To control a creature via a machine called cyborg method, three stages are considerable: stimulation of neurons, neural response, and the behavioral…

生物物理 · 物理学 2019-05-01 Mohammad Jamali , Yousef Jamali , Mehdi Golshani

A basal animal model is described as an organism similar to a Limpet that is attached to the sea floor living in a reproductive community. Its brain model uses logic cells (gates) to create a high frequency spike generator. Addition logic…

其他定量生物学 · 定量生物学 2016-12-19 Robert Alan Brown