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Many motile biological cells navigate along concentration gradients of signaling molecules: This chemotaxis guides for instance sperm cells from marine invertebrates, which have to find egg cells in the ocean. While chemotaxis has been…

生物物理 · 物理学 2022-09-21 Steffen Lange , Benjamin M. Friedrich

In this fluid mechanics video, we explore the kinematics of chemotaxing sperm cells (sea urchin, \textit{Arbacia punctulata}) swimming in a chemoattractant gradient. We demonstrate that the complex swimming trajectories resulting in…

流体动力学 · 物理学 2011-10-14 Jeffrey S. Guasto , Jeffrey A. Riffell , Richard K. Zimmer , Roman Stocker

Rheotaxis is a well-known phenomenon among microbial organisms and artificial active colloids, wherein the swimmers respond to an imposed flow. We report the first experimental evidence of upstream rheotaxis by spherical active droplets. It…

软凝聚态物质 · 物理学 2021-08-20 Prateek Dwivedi , Atishay Shrivastava , Dipin Pillai , Rahul Mangal

Active swimmers are ubiquitous in nature, found in many diverse biological systems ranging from bacteria to vertebrate fish. Of particular importance are sperm cells which are swimmers that are crucial for the survival of many species…

生物物理 · 物理学 2017-11-15 James L. Kingsley , Utkan Demirci , Erkan Tuzel

The propulsion of mammalian spermatozoa relies on the spontaneous periodic oscillation of their flagella. These oscillations are driven internally by the coordinated action of ATP-powered dynein motors that exert sliding forces between…

流体动力学 · 物理学 2022-10-13 Chenji Li , Brato Chakrabarti , Pedro Castilla , Achal Mahajan , David Saintillan

Sperm modulate their flagellar symmetry to navigate through complex physico-chemical environments and achieve reproductive function. Yet it remains elusive how sperm swim forwards despite the inherent asymmetry of several components that…

生物物理 · 物理学 2023-07-21 Xiaomeng Ren , Hermes Bloomfield-Gadêlha

In a low Reynolds number fluid environment that microswimmers encounter, back-and-forth motion cannot lead to net displacement. In mammalian sperm, the mechanical wave propagating along their single flagellum breaks the cancellation between…

Sperm are propelled by bending waves travelling along the flagellum. During steering in gradients of sensory cues, sperm adjust the flagellar beat waveform. Symmetric and asymmetric beat waveforms produce straight and curved swimming paths,…

Sperm swimming at low Reynolds number have strong hydrodynamic interactions when their concentration is high in vivo or near substrates in vitro. The beating tails not only propel the sperm through a fluid, but also create flow fields…

生物物理 · 物理学 2009-01-09 Yingzi Yang , Jens Elgeti , Gerhard Gompper

Chemotaxis, the directional locomotion of cells towards a source of a chemical gradient, is an integral part of many biological processes - for example, bacteria motion, single-cell or multicellular organisms development, immune response,…

偏微分方程分析 · 数学 2021-03-29 Yishu Gong , Alexander Kiselev

The migratory abilities of motile human spermatozoa in vivo are essential for natural fertility, but it remains a mystery what properties distinguish the tens of cells which find an egg from the millions of cells ejaculated. To reach the…

生物物理 · 物理学 2012-02-29 Petr Denissenko , Vasily Kantsler , David Smith , Jackson Kirkman-Brown

Due to their morphology, the dynamics of bacteria suspended in media can exhibit complex behaviors. In the presence of a shear, swimming bacteria experience a drift perpendicular to the shear plane. This drift, termed rheotaxis, is studied…

For navigation, microscopic agents such as biological cells rely on noisy sensory input. In cells performing chemotaxis, such noise arises from the stochastic binding of signaling molecules at low concentrations. Using chemotaxis of sperm…

Fish rheotaxis, or alignment into flow currents, results from intertwined sensory, neural and actuation mechanisms, all coupled with hydrodynamics to produce a behavior that is critical for upstream migration and position holding in…

流体动力学 · 物理学 2016-04-20 Brendan Colvert , Eva Kanso

Sperm swimming is crucial to fertilise the egg, in nature and in assisted reproductive technologies. Modelling the sperm dynamics involves elasticity, hydrodynamics, internal active forces, and out-of-equilibrium noise. Here we demonstrate…

软凝聚态物质 · 物理学 2023-06-26 C. Maggi , B. Nath , F. Saglimbeni , V. Carmona Sosa , R. Di Leonardo , A. Puglisi

Motivated by the swimming of sperm in the non-Newtonian fluids of the female mammalian reproductive tract, we examine the swimming of filaments in the nonlinear viscoelastic Upper Convected Maxwell model. We obtain the swimming velocity and…

软凝聚态物质 · 物理学 2009-11-13 Henry C. Fu , Thomas R. Powers , Charles W. Wolgemuth

Sperm cooperation has evolved in a variety of taxa and is often considered a response to sperm competition, yet the benefit of this form of collective movement remains unclear. Here we use fine-scale imaging and a minimal mathematical model…

细胞行为 · 定量生物学 2014-07-03 H. S. Fisher , L. Giomi , H. E. Hoekstra , L. Mahadevan

The journey of mammalian spermatozoa in nature is well-known to be reliant on their individual motility. Often swimming in crowded microenvironments, the progress of any single swimmer is likely dependent on their interactions with other…

流体动力学 · 物理学 2019-09-11 Benjamin J. Walker , Kenta Ishimoto , Eamonn A. Gaffney

For active particles the interplay between the self-generated hydrodynamic flow and an external shear flow, especially near bounding surfaces, can result in a rich behavior of the particles not easily foreseen from the consideration of the…

软凝聚态物质 · 物理学 2016-03-09 W. E. Uspal , M. N. Popescu , S. Dietrich , M. Tasinkevych

The guidance of human sperm cells under confinement in quasi 2D microchambers is investigated using a purely physical method to control their distribution. Transport property measurements and simulations are performed with dilute sperm…

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