相关论文: A New Preconditioner for the GeneRank Problem

Machine learning algorithms are used in diverse domains, many of which face significant challenges due to data imbalance. Studies have explored various approaches to address the issue, like data preprocessing, cost-sensitive learning, and…

In this work, we show how a genetic algorithm (GA) can be used to find step-by-step solutions to introductory physics problems. Our perspective is that the underlying task for this is one of finding a sequence of equations that will lead to…

Counterfactual learning has become promising for understanding and modeling causality in complex and dynamic systems. This paper presents a novel method for counterfactual learning in the context of multivariate time series analysis and…

This work discusses single-objective constrained genetic algorithm with floating-point, integer, binary and permutation representation. Floating-point genetic algorithm tuning with use of test functions is done and leads to a…

Background: Predictive, stable and interpretable gene signatures are generally seen as an important step towards a better personalized medicine. During the last decade various methods have been proposed for that purpose. However, one…

Ranking algorithms are deployed widely to order a set of items in applications such as search engines, news feeds, and recommendation systems. Recent studies, however, have shown that, left unchecked, the output of ranking algorithms can…

The PageRank algorithm is used to rank web pages by their importance. Since its development, the PageRank algorithm is a critical and fundamental part of search engines today. PageRank is a graph-based algorithm that ranks pages based on…

This study proposes a data condensation method for multivariate kernel density estimation by genetic algorithm. First, our proposed algorithm generates multiple subsamples of a given size with replacement from the original sample. The…

Solving the indefinite Helmholtz equation is not only crucial for the understanding of many physical phenomena but also represents an outstandingly-difficult benchmark problem for the successful application of numerical methods. Here we…

Reconstruction of gene regulatory networks is the process of identifying gene dependency from gene expression profile through some computation techniques. In our human body, though all cells pose similar genetic material but the activation…

Node influence metrics have been applied to many applications, including ranking web pages on internet, or locations on spatial networks. PageRank is a popular and effective algorithm for estimating node influence. However, conventional…

We present a novel classification-based method for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple organisms such as Saccharomyces cerevisiae, we can learn a decision rule for…

We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple organisms such as Saccharomyces cerevisiae, we can learn a…

In tumoral cells, gene regulation mechanisms are severely altered, and these modifications in the regulations may be characteristic of different subtypes of cancer. However, these alterations do not necessarily induce differential…

We study information theoretic methods for ranking biomarkers. In clinical trials there are two, closely related, types of biomarkers: predictive and prognostic, and disentangling them is a key challenge. Our first step is to phrase…

Google's PageRank method was developed to evaluate the importance of web-pages via their link structure. The mathematics of PageRank, however, are entirely general and apply to any graph or network in any domain. Thus, PageRank is now…

This paper explains genetic algorithm for novice in this field. Basic philosophy of genetic algorithm and its flowchart are described. Step by step numerical computation of genetic algorithm for solving simple mathematical equality problem…

The preconditioned conjugate gradient (PCG) algorithm is one of the most popular algorithms for solving large-scale linear systems Ax = b, where A is a symmetric positive definite matrix. Rather than computing residuals directly, it updates…

We present a novel preconditioning technique for proximal optimization methods that relies on graph algorithms to construct effective preconditioners. Such combinatorial preconditioners arise from partitioning the graph into forests. We…

Predicting protein interactions is one of the more interesting challenges of the post-genomic era. Many algorithms address this problem as a binary classification problem: given two proteins represented as two vectors of features, predict…