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The efficient construction of anatomical models is one of the major challenges of patient-specific in-silico models of the human heart. Current methods frequently rely on linear statistical models, allowing no advanced topological changes,…

We provide a rather simple proof of a homogenization result for the bidomain model of cardiac electrophysiology. Departing from a microscopic cellular model, we apply the theory of two-scale convergence to derive the bidomain model. To…

偏微分方程分析 · 数学 2018-11-20 Erik Grandelius , Kenneth H. Karlsen

Cardiovascular diseases, particularly heart failure, are a leading cause of death globally. The early detection of heart failure through routine echocardiogram screenings is often impeded by the high cost and labor-intensive nature of these…

图像与视频处理 · 电气工程与系统科学 2024-01-12 Ethan Thomas , Salman Aslam

Cardiac magnetic resonance imaging (MRI) is a pivotal tool for assessing cardiac function. Precise segmentation of cardiac structures is imperative for accurate cardiac functional evaluation. This paper introduces a semi-supervised model…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Hejun Huang , Zuguo Chen , Yi Huang , Guangqiang Luo , Chaoyang Chen , Youzhi Song

This chapter reviews the different methodological aspects of the ab ini-tio modeling of dislocations. Such simulations are now frequently used to study the dislocation core, i.e. the region in the immediate vicinity of the line defect where…

材料科学 · 物理学 2019-01-08 Emmanuel Clouet

The analysis of electrical impulse phenomena in cardiac muscle tissue is important for the diagnosis of heart rhythm disorders and other cardiac pathophysiology. Cardiac mapping techniques acquire local temporal measurements and combine…

医学物理 · 物理学 2022-03-21 Jan Lebert , Namita Ravi , Flavio Fenton , Jan Christoph

Reentry around non-conducting ventricular scar tissue, which often causes lethal arrhythmias, is typically treated by rapid stimulation from an implantable defibrillator. However, the mechanisms of termination (success and failure) are…

混沌动力学 · 物理学 2007-05-23 Sitabhra Sinha , David J. Christini

The rhythmic pumping motion of the heart stands as a cornerstone in life, as it circulates blood to the entire human body through a series of carefully timed contractions of the individual chambers. Changes in the size, shape and movement…

Accurate coronary artery segmentation from coronary computed tomography angiography is essential for quantitative coronary analysis and clinical decision support. Nevertheless, reliable segmentation remains challenging because of small…

计算机视觉与模式识别 · 计算机科学 2025-12-16 Huan Huang , Michele Esposito , Chen Zhao

This work is dedicated to the simulation of full cycles of the electrical activity of the heart and the corresponding body surface potential. The model is based on a realistic torso and heart anatomy, including ventricles and atria. One of…

医学物理 · 物理学 2015-09-04 Elisa Schenone , Annabelle Collin , Jean-Frédéric Gerbeau

Arrhythmias are potentially fatal disruptions to the normal heart rhythm, but their underlying dynamics is still poorly understood. Theoretical modeling is an important tool to fill this gap. Typical studies often employ detailed…

组织与器官 · 定量生物学 2022-03-08 R. V. Stenzinger , M. H. R. Tragtenberg

The ability to map left ventricle (LV) myocardial motion using computed tomography angiography (CTA) is essential to diagnosing cardiovascular conditions and guiding interventional procedures. Due to their inherent locality, conventional…

图像与视频处理 · 电气工程与系统科学 2024-11-08 Shahar Zuler , Shai Tejman-Yarden , Dan Raviv

Objective: Exploit accelerometry data for an automatic, reliable, and prompt detection of spontaneous circulation during cardiac arrest, as this is both vital for patient survival and practically challenging. Methods: We developed a machine…

信号处理 · 电气工程与系统科学 2023-02-13 Wolfgang J. Kern , Simon Orlob , Andreas Bohn , Wolfgang Toller , Jan Wnent , Jan-Thorsten Gräsner , Martin Holler

In this work, we investigate the numerical reconstruction of inclusions in a semilinear elliptic equation arising in the mathematical modeling of cardiac ischemia. We propose an adaptive finite element method for the resulting constrained…

数值分析 · 数学 2025-08-07 Bangti Jin , Fengru Wang , Yifeng Xu

The amount of fat on the surroundings of the heart is correlated to several health risk factors such as carotid stiffness, coronary artery calcification, atrial fibrillation, atherosclerosis, cancer incidence and others. Furthermore, the…

计算机视觉与模式识别 · 计算机科学 2026-05-29 É. O. Rodrigues , A. Conci , F. F. C. Morais , M. G. Pérez

Objectives: Atrial fibrillation (AF) is a common heart rhythm disorder associated with deadly and debilitating consequences including heart failure, stroke, poor mental health, reduced quality of life and death. Having an automatic system…

信号处理 · 电气工程与系统科学 2018-01-31 Philip Warrick , Masun Nabhan Homsi

Detecting anomalies in electrocardiogram data is crucial to identifying deviations from normal heartbeat patterns and providing timely intervention to at-risk patients. Various AutoEncoder models (AE) have been proposed to tackle the…

When generating in-silico clinical electrophysiological outputs, such as electrocardiograms (ECGs) and body surface potential maps (BSPMs), mathematical models have relied on single physics, i.e. of the cardiac electrophysiology (EP),…

Blood clots occur in the human body when they are required to prevent bleeding. In pathological states such as diabetes and sickle cell disease, blood clots can also form undesirably due to hypercoagulable plasma conditions. With the…

生物物理 · 物理学 2021-10-05 Tyler Scogin , Sumith Yesudasan , Mitchell L. R. Walker , Rodney D. Averett

The characterization of heart dynamics with a view to distinguish abnormal from normal behavior is an interesting topic in clinical sciences. Here we present an analysis of the Electro-cardiogram (ECG) signals obtained under controlled…

组织与器官 · 定量生物学 2018-09-05 Snehal M. Shekatkar , Yamini Kotriwar , K. P. Harikrishnan , G. Ambika