相关论文: Modeling the Complex Dynamics and Changing Correla…
We present the implementation of seizure detection algorithms based on a minimal number of EEG channels on a parallel ultra-low-power embedded platform. The analyses are based on the CHB-MIT dataset, and include explorations of different…
Epilepsy is a neurological disorder with recurrent seizures of complexity and randomness. Until now, the mechanism of epileptic randomness has not been fully elucidated. Inspired by the recent finding that astrocyte GTPase-activating…
Recent advances in neurotechnologies and decades of scientific and clinical research have made closed-loop electrical neuromodulation one of the most promising avenues for the treatment of drug-resistant epilepsy (DRE), a condition that…
Recent studies have shown that seizures can spread and terminate across brain areas via a rich diversity of spatiotemporal patterns. In particular, while the location of the seizure onset area is usually in-variant across seizures in a same…
In current clinical practice, electroencephalograms (EEG) are reviewed and analyzed by well-trained neurologists to provide supports for therapeutic decisions. The way of manual reviewing is labor-intensive and error prone. Automatic and…
Accurate epileptic seizure prediction from electroencephalography (EEG) remains challenging because pre-ictal dynamics may span long time horizons while clinically relevant signatures can be subtle and transient. Many deep learning models…
Epilepsy is a neurological brain disorder which life threatening and gives rise to recurrent seizures that are unprovoked. It occurs due to the abnormal chemical changes in our brain. Over the course of many years, studies have been…
Epilepsy creates a persistent increase in the probability of spontaneous seizures. An ictal episode evolves due to acute disturbance of the fine-tuned balance between excitatory vs. inhibitory inputs within a neural network in favor of…
In clinical practice, electroencephalography (EEG) plays an important role in the diagnosis of epilepsy. EEG-based computer-aided diagnosis of epilepsy can greatly improve the ac-curacy of epilepsy detection while reducing the workload of…
Alzheimer's disease (AD) alters brain electrophysiology and disrupts multichannel EEG dynamics, making accurate and clinically useful EEG-based diagnosis increasingly important for screening and disease monitoring. However, many existing…
Epilepsy is a chronic neurological disorder that affects a significant portion of the human population and imposes serious risks in the daily life of patients. Despite advances in machine learning and IoT, small, nonstigmatizing wearable…
During clinical treatment for epilepsy, the area of the brain thought to be responsible for pathological activity is identified. This identification is typically performed through visual assessment of EEG recordings; however, this is time…
The dynamics underlying epileptic seizures are well understood. We present a novel analysis of seizure-like events (SLEs) in an \textit{ex vivo} whole hippocampus, as well as a modeling study that sheds light on the underlying network…
Objective: Forecasting epileptic seizures can reduce uncertainty for patients and allow preventative actions. While many models can predict the occurrence of seizures from features of the EEG, few models incorporate changes in features over…
The brain is intrinsically organized into large-scale networks that constantly re-organize on multiple timescales, even when the brain is at rest. The timing of these dynamics is crucial for sensation, perception, cognition and ultimately…
Parkinsons disease (PD) alters cortical neural dynamics, yet reliable non-invasive electrophysiological biomarkers remain elusive. This study examined whether interpretable EEG features capturing complementary aspects of neural dynamics can…
An ability to map seizure-generating brain tissue, i.e., the seizure onset zone (SOZ), without recording actual seizures could reduce the duration of invasive EEG monitoring for patients with drug-resistant epilepsy. A widely-adopted…
Seizure forecasting may provide patients with timely warnings to adapt their daily activities and help clinicians deliver more objective, personalized treatments. While recent work has convincingly demonstrated that seizure risk assessment…
Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of…
Epilepsy is a network disease. The epileptic network usually involves spatially distributed brain regions. In this context, noninvasive M/EEG source connectivity is an emerging technique to identify functional brain networks at cortical…