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Substrate-based cell motility is essential for fundamental biological processes, such as tissue growth, wound healing and immune response. Even if a comprehensive understanding of this motility mode remains elusive, progress has been…

细胞行为 · 定量生物学 2016-05-23 Wieland Marth , Axel Voigt

Sedimentation in active fluids has come into focus due to the ubiquity of swimming micro-organisms in natural and industrial processes. Here, we investigate sedimentation dynamics of passive particles in a fluid as a function of bacteria E.…

How does the interplay between selection, mutation and horizontal gene transfer modify the phenotypic distribution of a bacterial or cell population? While horizontal gene transfer, which corresponds to the exchange of genetic material…

偏微分方程分析 · 数学 2023-02-08 Alejandro Gárriz , Alexis Léculier , Sepideh Mirrahimi

Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…

物理与社会 · 物理学 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

Range expansion is a universal process in biological systems, and therefore plays a part in biological evolution. Using a quantitative individual-based method based on the stochastic process, we identify that enhancing the inherent…

种群与进化 · 定量生物学 2022-01-17 Xiaoliang Wang , Andrew Harrison

In genetic drift of small population, it is well known that even when the ratio of alleles is 0.5, specific genes are fixed in or disappear from the population. It seems the reason why inbreeding is avoided. On the other hand, this…

种群与进化 · 定量生物学 2018-05-08 Hiroshi Isshiki

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

生物物理 · 物理学 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

Microbial interactions regulate their spread and survival in competitive environments. It is not clear if the physical parameters of the environment regulate the outcome of these interactions. In this work, we show that the opportunistic…

细胞行为 · 定量生物学 2023-09-12 Divakar Badal , Aloke Kumar , Varsha Singh , Danny Raj M

Immotile microbes inhabit nearly every environment on Earth, from soils and sediments to food matrices -- yet how they disperse through these physically confining environments is poorly understood. Here, we show that immotile microbial…

The dynamics of growth of bacterial populations has been extensively studied for planktonic cells in well-agitated liquid culture, in which all cells have equal access to nutrients. In the real world, bacteria are more likely to live in…

种群与进化 · 定量生物学 2017-11-01 Xinxian Shao , Andrew Mugler , Justin Kim , Ha Jun Jeong , Bruce Levin , Ilya Nemenman

The ~4-Mbp basic genome shared by 32 independent isolates of E. coli representing considerable population diversity has been approximated by whole-genome multiple-alignment and computational filtering designed to remove mobile elements and…

种群与进化 · 定量生物学 2014-05-13 Purushottam Dixit , Tin Yau Pang , F. William Studier , Sergei Maslov

Bacteria and archaea have evolved an adaptive, heritable immune system that recognizes and protects against viruses or plasmids. This system, known as the CRISPR-Cas system, allows the host to recognize and incorporate short foreign DNA or…

种群与进化 · 定量生物学 2014-01-21 Pu Han , Liang Ren Niestemski , Jeffrey E. Barrick , Michael W. Deem

Bacteria organize in a variety of collective states, from swarming, which has been attributed to rapid surface exploration, to biofilms, which are highly dense immobile communities attributed to stress resistance. It has been suggested that…

The spatial organization of bacteria in dense biofilms is key to their collective behaviour, and understanding it will be important for medical and technological applications. Here we study the morphology of a compact biofilm that undergoes…

生物物理 · 物理学 2019-03-05 Xin Wang , Howard A. Stone , Ramin Golestanian

Gliding is a means of locomotion on rigid substrates utilized by a number of bacteria includingmyxobacteria and cyanobacteria. One of the hypotheses advanced to explain this motility mechanism hinges on the role played by the slime…

生物物理 · 物理学 2015-03-02 Epifanio G. Virga

During colony growth, complex interactions regulate the bacterial orientation, leading to the formation of large-scale ordered structures, including topological defects and microdomains. These structures may benefit bacterial strains,…

生物物理 · 物理学 2024-04-10 Mustafa Başaran , Y. Ilker Yaman , Tevfik Can Yuce , Roman Vetter , Askin Kocabas

Bacteria commonly inhabit porous environments such as host tissues, soil, and marine sediments, where complex geometries constrain and redirect their motion. Although bacterial motility has been studied in porous media, the roles of cell…

软凝聚态物质 · 物理学 2025-12-22 David Gao , Zeyuan Wang , Mihika Jain , Arnold J. T. M. Mathijssen , Ran Tao

We introduce and analyze a model for osmotically spreading biofilm colonies at solid-air interfaces that includes wetting phenomena, i.e. surface forces. The model combines a hydrodynamic description for biologically passive liquid…

生物物理 · 物理学 2017-08-23 Sarah Trinschek , Karin John , Sigolène Lecuyer , Uwe Thiele

Due to their morphology, the dynamics of bacteria suspended in media can exhibit complex behaviors. In the presence of a shear, swimming bacteria experience a drift perpendicular to the shear plane. This drift, termed rheotaxis, is studied…

Bacteria suspension exhibits a wide range of collective phenomena arising from interactions between individual cells. Here we show Serratia marcescens cells near an air-liquid interface spontaneously aggregate into dynamic clusters through…

软凝聚态物质 · 物理学 2015-09-30 Xiao Chen , Xiang Yang , Mingcheng Yang , Hepeng Zhang
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