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Modeling the absorbed dose during X-ray imaging is essential for optimizing radiation exposure. Monte Carlo simulations (MCS) are the gold standard for precise 3D dose estimation but require significant computation time. Deep learning…

医学物理 · 物理学 2025-02-14 Maxime Rousselot , Jing Zhang , Didier Benoit , Chi-Hieu Pham , Julien Bert

Discrete-state stochastic models have become a well-established approach to describe biochemical reaction networks that are influenced by the inherent randomness of cellular events. In the last years severalmethods for accurately…

分子网络 · 定量生物学 2017-07-03 Alexander Lück , Verena Wolf

Nonlinear mixed effects models have become a standard platform for analysis when data is in the form of continuous and repeated measurements of subjects from a population of interest, while temporal profiles of subjects commonly follow a…

统计方法学 · 统计学 2022-03-04 Se Yoon Lee

In Oncology, trials evaluating drug combinations are becoming more common. While combination therapies bring the potential for greater efficacy, they also create unique challenges for ensuring drug safety. In Phase-I dose escalation trials…

应用统计 · 统计学 2023-02-23 Lukas A. Widmer , Andrew Bean , David Ohlssen , Sebastian Weber

The counterfactual distribution models the effect of the treatment in the untreated group. While most of the work focuses on the expected values of the treatment effect, one may be interested in the whole counterfactual distribution or…

机器学习 · 统计学 2022-11-04 Diego Martinez-Taboada , Dino Sejdinovic

In the present paper, we derive lower bounds for the risk of the nonparametric empirical Bayes estimators. In order to attain the optimal convergence rate, we propose generalization of the linear empirical Bayes estimation method which…

统计理论 · 数学 2013-06-12 Rida Benhaddou , Marianna Pensky

Complex data features, such as unmodelled censored event times and variables with time-dependent effects, are common in cancer recurrence studies and pose challenges for Bayesian survival modelling. Current methodologies for predictive…

统计方法学 · 统计学 2026-01-12 Saku Suorsa , Aki Vehtari

Existing language model safety evaluations focus on overt attacks and low-stakes tasks. In reality, an attacker can easily subvert existing safeguards by requesting help on small, benign-seeming tasks across many independent queries.…

密码学与安全 · 计算机科学 2026-04-22 Davis Brown , Mahdi Sabbaghi , Luze Sun , Alexander Robey , George J. Pappas , Eric Wong , Hamed Hassani

In inverse problems, the parameters of a model are estimated based on observations of the model response. The Bayesian approach is powerful for solving such problems; one formulates a prior distribution for the parameter state that is…

统计计算 · 统计学 2022-06-08 Max Ehre , Rafael Flock , Martin Fußeder , Iason Papaioannou , Daniel Straub

We propose Bayesian model averaging (BMA) as a method for postprocessing the results of model-based clustering. Given a number of competing models, appropriate model summaries are averaged, using the posterior model probabilities, instead…

统计计算 · 统计学 2015-07-01 Niamh Russell , Thomas Brendan Murphy , Adrian E Raftery

Conformal prediction has emerged as a popular technique for facilitating valid predictive inference across a spectrum of machine learning models, under minimal assumption of exchangeability. Recently, Hoff (2023) showed that full conformal…

统计理论 · 数学 2025-11-24 Pankaj Bhagwat , Linglong Kong , Bei Jiang

Quality control in industrial processes is increasingly making use of prior scientific knowledge, often encoded in physical models that require numerical approximation. Statistical prediction, and subsequent optimization, is key to ensuring…

其他统计学 · 统计学 2018-10-23 Antony Overstall , David Woods , Kieran Martin

We present global predictions of the ground state mass of atomic nuclei based on a novel Machine Learning (ML) algorithm. We combine precision nuclear experimental measurements together with theoretical predictions of unmeasured nuclei.…

核理论 · 物理学 2023-04-19 M. R. Mumpower , M. Li , T. M. Sprouse , B. S. Meyer , A. E. Lovell , A. T. Mohan

Radio map estimation (RME) is the problem of inferring the value of a certain metric (e.g. signal power) across an area of interest given a collection of measurements. While most works tackle this problem from a purely non-Bayesian…

信号处理 · 电气工程与系统科学 2025-08-11 Tien Ngoc Ha , Daniel Romero

In statistical exercises where there are several candidate models, the traditional approach is to select one model using some data driven criterion and use that model for estimation, testing and other purposes, ignoring the variability of…

统计理论 · 数学 2008-12-18 Snigdhansu Chatterjee , Nitai D. Mukhopadhyay

This paper proposes a simple, novel, and fully-Bayesian approach for causal inference in partially linear models with high-dimensional control variables. Off-the-shelf machine learning methods can introduce biases in the causal parameter…

计量经济学 · 经济学 2025-08-19 Francis J. DiTraglia , Laura Liu

We introduce a novel procedure for obtaining cross-validated predictive estimates for Bayesian hierarchical regression models (BHRMs). Bayesian hierarchical models are popular for their ability to model complex dependence structures and…

机器学习 · 统计学 2024-10-01 Amy X. Zhang , Le Bao , Changcheng Li , Michael J. Daniels

Histogram-based empirical Bayes methods developed for analyzing data for large numbers of genes, SNPs, or other biological features tend to have large biases when applied to data with a smaller number of features such as genes with…

统计方法学 · 统计学 2013-10-10 Marta Padilla , David R. Bickel

We consider the Bayesian estimation of the parameters of a finite mixture model from independent order statistics arising from imperfect ranked set sampling designs. As a cost-effective method, ranked set sampling enables us to incorporate…

Ideally, a meta-analysis will summarize data from several unbiased studies. Here we consider the less than ideal situation in which contributing studies may be compromised by measurement error. Measurement error affects every study design,…