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We propose a novel supervised learning method to optimize the kernel in the maximum mean discrepancy generative adversarial networks (MMD GANs), and the kernel support vector machines (SVMs). Specifically, we characterize a distributionally…

机器学习 · 计算机科学 2020-02-25 Masoud Badiei Khuzani , Liyue Shen , Shahin Shahrampour , Lei Xing

Objective: In modern healthcare, accurately predicting diseases is a crucial matter. This study introduces a novel approach using graph neural networks (GNNs) and a Graph Transformer (GT) to predict the incidence of heart failure (HF) on a…

机器学习 · 计算机科学 2025-06-23 Heloisa Oss Boll , Ali Amirahmadi , Amira Soliman , Stefan Byttner , Mariana Recamonde-Mendoza

A common problem in bioinformatics is related to identifying gene regulatory regions marked by relatively high frequencies of motifs, or deoxyribonucleic acid sequences that often code for transcription and enhancer proteins. Predicting…

基因组学 · 定量生物学 2021-01-22 Ethan Jacob Moyer , Anup Das

Early identification of stroke is crucial for intervention, requiring reliable models. We proposed an efficient retinal image representation together with clinical information to capture a comprehensive overview of cardiovascular health,…

计算机视觉与模式识别 · 计算机科学 2024-11-11 Yuqing Huang , Bastian Wittmann , Olga Demler , Bjoern Menze , Neda Davoudi

The early detection and prediction of cardiovascular diseases are crucial for reducing the severe morbidity and mortality associated with these conditions worldwide. A multi-headed self-attention mechanism, widely used in natural language…

This paper proposes a novel meta-learning based hyper-parameter optimization framework for wireless network traffic prediction (NTP) models. The primary objective is to accumulate and leverage the acquired hyper-parameter optimization…

网络与互联网体系结构 · 计算机科学 2025-05-06 Liangzhi Wang , Jie Zhang , Yuan Gao , Jiliang Zhang , Guiyi Wei , Haibo Zhou , Bin Zhuge , Zitian Zhang

Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within…

统计方法学 · 统计学 2013-02-26 M. Silver , P. Chen , L. Ruoying , C. Y. Cheng , T. Y. Wong , E. Tai , Y. Y. Teo , G. Montana

We propose a non-parametric regression methodology, Random Forests on Distance Matrices (RFDM), for detecting genetic variants associated to quantitative phenotypes representing the human brain's structure or function, and obtained using…

机器学习 · 统计学 2013-09-25 Aaron Sim , Dimosthenis Tsagkrasoulis , Giovanni Montana

Background: Identification of causal SNPs in most genome wide association studies relies on approaches that consider each SNP individually. However, there is a strong correlation structure among SNPs that need to be taken into account.…

应用统计 · 统计学 2012-11-02 Verena Zuber , A. Pedro Duarte Silva , Korbinian Strimmer

We propose a resampling-based fast variable selection technique for detecting relevant single nucleotide polymorphisms (SNP) in a multi-marker mixed effect model. Due to computational complexity, current practice primarily involves testing…

应用统计 · 统计学 2025-04-30 Subhabrata Majumdar , Saonli Basu , Matt McGue , Snigdhansu Chatterjee

Investigation on the electrocardiogram (ECG) signals is an essential way to diagnose heart disease since the ECG process is noninvasive and easy to use. This work presents a supraventricular arrhythmia prediction model consisting of a few…

信号处理 · 电气工程与系统科学 2021-12-28 Pampa Howladar , Manodipan Sahoo

We preprocess the raw NMR spectrum and extract key characteristic features by using two different methodologies, called equidistant sampling and peak sampling for subsequent substructure pattern recognition; meanwhile may provide the…

定量方法 · 定量生物学 2021-07-27 Chongcan Li , Yong Cong , Weihua Deng

Cardiovascular disease is one of the most challenging diseases in middle-aged and older people, which causes high mortality. Coronary artery disease (CAD) is known as a common cardiovascular disease. A standard clinical tool for diagnosing…

Coronary heart disease (CHD) is a leading cause of death worldwide and contributes significantly to annual healthcare expenditures. To develop a non-invasive diagnostic approach, we designed a model based on a multilayer perceptron (MLP)…

机器学习 · 计算机科学 2025-09-05 Jesus Celis-Porras

We propose a simple algorithm that needs only a few data samples from a single graph for learning local routing policies that generalize across a rich class of geometric random graphs in Euclidean metric spaces. We thus solve the all-pairs…

机器学习 · 计算机科学 2025-09-09 Yung-Fu Chen , Sen Lin , Anish Arora

In today's world, a massive amount of data is available in almost every sector. This data has become an asset as we can use this enormous amount of data to find information. Mainly health care industry contains many data consisting of…

机器学习 · 计算机科学 2022-03-10 Hafsa Binte Kibria , Abdul Matin

Abstract: Background: Understanding cardiovascular artery disease risk factors, the leading global cause of mortality, is crucial for influencing its etiology, prevalence, and treatment. This study aims to evaluate prognostic markers for…

机器学习 · 计算机科学 2025-01-17 Bami Zahra , Behnampour Nasser , Doosti Hassan , Ghayour Mobarhan Majid

Diagnosis and risk stratification of cancer and many other diseases require the detection of genomic breakpoints as a prerequisite of calling copy number alterations (CNA). This, however, is still challenging and requires time-consuming…

Chronic diseases, such as cardiovascular disease, diabetes, chronic kidney disease, and thyroid disorders, are the leading causes of premature mortality worldwide. Early detection and intervention are crucial for improving patient outcomes,…

机器学习 · 计算机科学 2025-11-04 Houda Belhad , Asmae Bourbia , Salma Boughanja

We present a meta-analysis of independent studies on the potential implication in the occurrence of coronary heart disease (CHD) of the single-nucleotide polymorphism (SNP) at the -308 position of the tumor necrosis factor alpha (TNF-alpha)…

定量方法 · 定量生物学 2015-09-18 C. Sofia Carvalho