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Cilia and flagella often exhibit synchronized behavior; this includes phase locking, as seen in {\it Chlamydomonas}, and metachronal wave formation in the respiratory cilia of higher organisms. Since the observations by Gray and Rothschild…

软凝聚态物质 · 物理学 2016-05-19 Kirsty Y. Wan , Raymond E. Goldstein

Groups of beating flagella or cilia often synchronize so that neighboring filaments have identical frequencies and phases. A prime example is provided by the unicellular biflagellate Chlamydomonas reinhardtii, which typically displays…

Despite evidence for a hydrodynamic origin of flagellar synchronization between different eukaryotic cells, recent experiments have shown that in single multi-flagellated organisms, coordination hinges instead on direct basal body…

生物物理 · 物理学 2018-10-12 Yujie Liu , Rory Claydon , Marco Polin , Douglas R. Brumley

The unicellular microalga Chlamydomonas reinhardtii (CR) is well known for its bi-flagellated swimming in response to light stimuli. This work aims to study the resynchronization of CR flagella after a high light intensity stimulus, known…

生物物理 · 物理学 2026-02-20 Lucas Federspiel , Jorge Arrieta , Marco Polin , Francoise Argoul , Antoine Allard

Cilia and flagella are essential building blocks for biological fluid transport and locomotion at the micron scale. They often beat in synchrony and may transition between different synchronization modes in the same cell type. Here, we…

流体动力学 · 物理学 2018-02-14 Hanliang Guo , Lisa Fauci , Michael Shelley , Eva Kanso

Beating flagella exhibit a variety of synchronization modes. This synchrony has long been attributed to hydrodynamic coupling between the flagella. However, recent work with flagellated algae indicates that a mechanism internal to the cell,…

生物物理 · 物理学 2020-11-18 Hanliang Guo , Yi Man , Kirsty Y. Wan , Eva Kanso

We present a theory of flagellar synchronization in the green alga Chlamydomonas, using full treatment of flagellar hydrodynamics. We find that two recently proposed synchronization mechanisms, basal coupling and flagellar waveform…

细胞行为 · 定量生物学 2018-01-17 G. S. Klindt , C. Ruloff , C. Wagner , B. M. Friedrich

While hydrodynamic coupling has long been considered essential for synchronisation of eukaryotic flagella, recent experiments on the unicellular biflagellate model organism {\it Chlamydomonas} demonstrate that -- at the single cell level --…

生物物理 · 物理学 2025-04-04 Luc Zorrilla , Antoine Allard , Krish Desai , Marco Polin

The motility of microorganisms is influenced greatly by their hydrodynamic interactions with the fluidic environment they inhabit. We show by direct experimental observation of the bi-flagellated alga Chlamydomonas reinhardtii that fluid…

生物物理 · 物理学 2015-11-03 Boyang Qin , Arvind Gopinath , Jing Yang , Jerry P Gollub , Paulo E Arratia

Synchronisation is often observed in the swimming of flagellated cells, either for multiple appendages on the same organism or between the flagella of nearby cells. Beating cilia are also seen to synchronise their dynamics. In 1951, Taylor…

生物物理 · 物理学 2021-04-28 Weida Liao , Eric Lauga

The unicellular green algae Chlamydomonas swims with two flagella, which can synchronize their beat. Synchronized beating is required to swim both fast and straight. A long-standing hypothesis proposes that synchronization of flagella…

细胞行为 · 定量生物学 2013-11-26 Veikko Geyer , Frank Jülicher , Jonathon Howard , Benjamin M Friedrich

Living creatures exhibit a remarkable diversity of locomotion mechanisms, evolving structures specialised for interacting with their environment. In the vast majority of cases, locomotor behaviours such as flying, crawling, and running, are…

生物物理 · 物理学 2020-07-28 Kirsty Y. Wan

Cilia and flagella exhibit regular bending waves that perform mechanical work on the surrounding fluid, to propel cellular swimmers and pump fluids inside organisms. Here, we quantify a force-velocity relationship of the beating flagellum,…

细胞行为 · 定量生物学 2016-12-21 Gary S. Klindt , Christian Ruloff , Christian Wanger , Benjamin M. Friedrich

Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves". These are beautiful examples of emergent dynamics in biology, and are essential for…

软凝聚态物质 · 物理学 2016-04-20 Nicolas Bruot , Pietro Cicuta

Cellular appendages such as cilia and flagella represent universal tools enabling cells and microbes, among other essential functionalities, to propel themselves in diverse environments. In its planktonic, i.e. freely swimming, state the…

Biological microfilaments exhibit a variety of synchronization modes. Recent experiments observed that a pair of isolated eukaryotic flagella, coupled solely via the fluid medium, display synchrony at nontrivial phase-lags in addition to…

生物物理 · 物理学 2020-10-28 Yi Man , Eva Kanso

The green alga {\it Chlamydomonas} swims with synchronized beating of its two flagella, and is experimentally observed to exhibit run-and-tumble behaviour similar to bacteria. Recently we studied a simple hydrodynamic three-sphere model of…

软凝聚态物质 · 物理学 2015-06-15 Rachel R. Bennett , Ramin Golestanian

In this fluid dynamics video, we demonstrate the microscale mixing enhancement of passive tracer particles in suspensions of swimming microalgae, Chlamydomonas reinhardtii. These biflagellated, single-celled eukaryotes (10 micron diameter)…

Eukaryotes swim with coordinated flagellar (ciliary) beating and steer by fine-tuning the coordination. The model organism for studying flagellate motility, C. reinhardtii (CR), employs synchronous, breast-stroke-like flagellar beating to…

生物物理 · 物理学 2024-06-12 Da Wei , Greta Quaranta , Marie-Eve Aubin-Tam , Daniel S. W. Tam

Synchronization induced by long-range hydrodynamic interactions is attracting attention as a candidate mechanism behind coordinated beating of cilia and flagella. Here we consider a minimal model of hydrodynamic synchronization in the low…

软凝聚态物质 · 物理学 2012-11-26 Nariya Uchida , Ramin Golestanian
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