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Currently, a large number of stored tissue samples are unavailable for spectroscopic study without the time consuming and destructive process of paraffin removal. Instead, a structurally sensitive technique, sum frequency generation, and a…

医学物理 · 物理学 2023-10-03 Bryan Semon , Michael Jaffe , Haifeng Wang , Lauren Priddy , Gombojav Ariunbold

Using optical speckle scanning microscopy [1], we demonstrate that clear images of multiple cells can be obtained through biological scattering tissue, with subcellular resolution and good image quality, as long as the size of the imaging…

光学 · 物理学 2023-07-19 Xin Yang , Ye Pu , Demetri Psaltis

This work introduces a quantitative method for assessing calcification in fibrocartilage using spectral micro-computed tomography ($\mu$CT). Tissue samples of hip acetabular labrum from patients with osteoarthritis and femoroacetabular…

Signal models based on sparse representations have received considerable attention in recent years. On the other hand, deep models consisting of a cascade of functional layers, commonly known as deep neural networks, have been highly…

图像与视频处理 · 电气工程与系统科学 2022-01-19 Xikai Yang , Yong Long , Saiprasad Ravishankar

The MARS scanner is designed for the x-ray spectroscopic study of samples with the aid of computer tomography methods. Computer tomography allows the reconstruction of slices of an investigated sample using a set of shadow projections…

Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. Contrast-enhanced spectral imaging has been thoroughly investigated,…

医学物理 · 物理学 2021-01-26 Erik Fredenberg , Magnus Aslund , Bjorn Cederstrom , Mats Lundqvist , Mats Danielsson

Differentiation of breast tissues is challenging in X-ray imaging because tissues might share similar or even the same linear attenuation coefficients $\mu$. Spectral computed tomography (CT) allows for more quantitative characterization in…

Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring…

天体物理仪器与方法 · 物理学 2018-10-09 Elmar Schmälzlin , Benito Moralejo , Ingo Gersonde , Johannes Schleusener , Maxim E. Darvin , Gisela Thiede , Martin M. Roth

Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the…

Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. The authors have investigated a photon-counting spectral…

Multi-spectral computed tomography is an emerging technology for the non-destructive identification of object materials and the study of their physical properties. Applications of this technology can be found in various scientific and…

计算机视觉与模式识别 · 计算机科学 2018-10-30 Christian Kehl , Wail Mustafa , Jan Kehres , Anders Bjorholm Dahl , Ulrik Lund Olsen

Methods to visualize the two-dimensional distribution of molecules by mass spectrometric imaging evolve rapidly and yield novel applications in biology, medicine, and material surface sciences. Most mass spectrometric imagers acquire high…

仪器与探测器 · 物理学 2011-03-11 Casimir Bamberger , Uwe Renz , Andreas Bamberger

Material decomposition for imaging multiple contrast agents in a single acquisition has been made possible by spectral CT: a modality which incorporates multiple photon energy spectral sensitivities into a single data collection. This work…

医学物理 · 物理学 2020-08-11 Matthew Tivnan , Steven Tilley , J. Webster Stayman

Label-free vibrational imaging by stimulated Raman scattering (SRS) provides unprecedented insight into real-time chemical distributions in living systems. Specifically, SRS in the fingerprint region can resolve multiple chemicals in a…

Coherent anti-Stokes Raman Spectroscopy (CARS) is a laser-based measurement technique widely applied across many science and engineering disciplines to perform non-intrusive gas diagnostics. CARS is often used to study combustion, where the…

机器学习 · 计算机科学 2022-05-25 Gregory J. Hunt , Cody R. Ground , Andrew D. Cutler

The rapid and accurate detection of biochemical compositions in fish is a crucial real-world task that facilitates optimal utilization and extraction of high-value products in the seafood industry. Raman spectroscopy provides a promising…

Laser-induced breakdown spectroscopy (LIBS) is a popular, fast elemental analysis technique used to determine the chemical composition of target samples, such as in industrial analysis of metals or in space exploration. Recently, there has…

机器学习 · 计算机科学 2021-04-10 Kshitij Bhardwaj , Maya Gokhale

We introduce the soft curvature and spectroscopy (SCANS) system: a versatile, electronics-free, fluidically actuated soft manipulator capable of assessing the spectral properties of objects either in hand or through pre-touch caging. This…

机器人学 · 计算机科学 2025-10-03 Nathaniel Hanson , Austin Allison , Charles DiMarzio , Taşkın Padır , Kristen L. Dorsey

Existing learning models often utilise CT-scan images to predict lung diseases. These models are posed by high uncertainties that affect lung segmentation and visual feature learning. We introduce MARL, a novel Multimodal Attentional…

计算机视觉与模式识别 · 计算机科学 2021-05-04 Ali Hamdi , Amr Aboeleneen , Khaled Shaban

Hyperspectral imaging provides high-dimensional spatial-temporal-spectral information revealing intrinsic matter characteristics. Here we report an on-chip computational hyperspectral imaging framework with high spatial and temporal…

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