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Diamond nanoparticles (nanodiamonds) have been recently proposed as new labels for cellular imaging. For small nanodiamonds (size <40 nm) resonant laser scattering and Raman scattering cross-sections are too small to allow single…

Diamond nanoparticles (nanodiamonds) can transport active drugs in cultured cells as well as in vivo. However, in the latter case, methods allowing to determine their bioavailability accurately are still lacking. Nanodiamond can be made…

Fluorescent nanodiamonds (FNDs) relaxometry holds promising future for advancement of high spatiotemporal resolution metabolic imaging technology. In this study, we demonstrate a simultaneous integration of spatial position tracking with…

生物物理 · 物理学 2025-12-23 Jia Su , Linyu Zeng , Pengyu Chen , Zenghao Kong , Fazhan Shi

Dynamics of active or self-propulsive Brownian particles in nonequilibrium status, has recently attracted great interest in many fields including biological entities and artificial micro/nanoscopic motors6. Understanding of their dynamics…

软凝聚态物质 · 物理学 2017-01-18 Xuewen Fu , Bin Chen , Jau Tang , Ahmed H. Zewail

Integration of optically-active nanodiamonds with glass fibers is a powerful method of scaling of diamond magnetic sensing functionality. We propose a novel approach for integration of nanodiamonds containing nitrogen-vacancy centers…

Brownian motion provides access to hydrodynamic properties of nanoscale objects independent of their optical resolvability. Here, we present a diffusion-based approach to infer effective particle size distributions of DNA-functionalized…

Understanding the dynamics of molecules adsorbed to surfaces or confined to small volumes is a matter of increasing scientific and technological importance. Here, we demonstrate a pulse protocol using individual paramagnetic nitrogen…

介观与纳米尺度物理 · 物理学 2015-10-28 T. Staudacher , N. Raatz , S. Pezzagna , J. Meijer , F. Reinhard , C. A. Meriles , J. Wrachtrup

Traditional cellular force-sensing techniques, such as traction force microscopy (TFM), are predominantly limited to measuring linear tractions, overlooking and technically unable to capture the nanoscale torsional forces that are critical…

Benefitting from the excellent characteristics such as low cytotoxicity, functionalization versatility, and tunable fluorescence, nanodiamonds (NDs) have shown enormous application potentials in the biomedical field. Herein, we proposed,…

光学 · 物理学 2022-03-01 Yaofei Chen , Lu Xiao , Longqun Ni , Lei Chen , Gui-shi Liu , Jinde Yin , Peili Zhao , Yunhan Luo , Zhe Chen

Diatoms are characterised by silica cell walls (frustules), which have highly ordered micro-/nano-structures. As the synthesis of such structures remains challenging, diatom frustules offer a promissing alternative to conventional porous…

介观与纳米尺度物理 · 物理学 2024-10-24 Naoki Tomioka , Yusaku Abe , Yu Matsuda

High biocompatibility, variable size ranging from ~ 5 nm, stable luminescence from its color centers and simple carbon chemistry for biomolecule grafting make nanodiamond (ND) particles an attractive alternative to molecular dyes for…

Color centers in diamond nanocrystals are a new class of fluorescence markers that attract significant interest due to matchless brightness, photostability and biochemical inertness. Fluorescing diamond nanocrystals containing defects can…

生物大分子 · 定量生物学 2009-11-13 M. Boersch , R. Reuter , G. Balasubramanian , R. Erdmann , F. Jelezko , J. Wrachtrup

Nanodiamonds containing luminescent point defects are widely explored for applications in quantum bio-sensing such as nanoscale magnetometry, thermometry, and electrometry. A key challenge in the development of such applications is a large…

光学 · 物理学 2023-02-08 Qiang Sun , Shuo Li , Taras Plakhotnik , Andrew D. Greentree

The prospect of RNA nanotechnology is increasing because of its numerous potential applications especially in medical science. The spherical Nanodiamonds (NDs) are becoming popular because of their lesser toxicity, desirable mechanical,…

The determination of particle size by dynamic light scattering uses the Stokes-Einstein relation, which can break down for nanoscale objects. Here we employ a molecular dynamics simulation of fully solvated 1-5 nm carbon nanoparticles for…

流体动力学 · 物理学 2016-09-07 S. V. Koniakhin , I. E. Eliseev , I. N. Terterov , A. V. Shvidchenko , E. D. Eidelman , M. V. Dubina

Functionality of living cells is inherently linked to subunits with dimensions on the nanoscale. In case of osteoblasts the cell surface plays a particularly important role for adhesion and spreading which are crucial properties with regard…

生物物理 · 物理学 2020-11-30 C. Voelkner , M. Wendt , R. Lange , M. Ulbrich , M. Gruening , S. Staehlke , J. B. Nebe , I. Barke , S. Speller

There is a growing need for biolabels that can be used in both optical and electron microscopies, are non-cytotoxic, and do not photobleach. Such biolabels could enable targeted nanoscale imaging of sub-cellular structures, and help to…

生物物理 · 物理学 2015-06-23 Mark A. Zurbuchen , Michael P. Lake , Sirus A. Kohan , Belinda Leung , Louis-S. Bouchard

Structured environment controls dynamics of light-matter interaction processes via modified local density of electromagnetic states. In typical scenarios, where nanosecond-scale fluorescent processes are involved, mechanical conformational…

The chemical vapor deposition of polycrystalline diamond (PCD) films is typically done on substrates seeded with diamond nanoparticles. Specular laser reflectance and a continuous film model have been used to monitor the thickness of these…

材料科学 · 物理学 2023-01-31 David Vázquez-Cortés , Stoffel D. Janssens , Burhannudin Sutisna , Eliot Fried

We measure diffusion of organic molecules located a few nanometers from the diamond surface. To study molecular diffusion, we perform local detection of nuclear magnetic resonance, based on single shallow Nitrogen-Vacancy (NV) centers in…

介观与纳米尺度物理 · 物理学 2021-05-18 Farida Shagieva , Andrea Zappe , Daniel Cohen , Andrej Denisenko , Alex Retzker , Jörg Wrachtrup
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