相关论文: Pre-treatment radiotherapy dose verification using…
Conventional radiotherapy dose calculation algorithms are often computationally slow and non-differentiable, creating bottlenecks for online adaptive radiotherapy (ART) and limiting end-to-end automatic planning. Deep learning provides…
Complex Semi-Definite Programming (SDP) is introduced as a novel approach to phase retrieval enabled control of monochromatic light transmission through highly scattering media. In a simple optical setup, a spatial light modulator is used…
With X-ray radiation protection and dose management constantly gaining interest in interventional radiology, novel procedures often undergo prospective dose studies using anthropomorphic phantoms to determine expected dose values. Due to…
Flattening filter free (FFF) beams due to their non-uniformity, are sub-optimal for larger field sizes. The purpose of this study was to investigate the incident electron beam distributions that would produce flat FFF beams without the use…
While Dark Matter (DM) is typically assumed to interact only very weakly with the particles of the Standard Model, many direct detection experiments are currently exploring regions of parameter space where DM can have a large scattering…
Very high energy electrons (VHEE) in the 50-250 MeV range, delivered in short pulses at ultra-high dose rates, are proposed for clinical FLASH radiotherapy (RT) targeting deep-seated tumors. The clinical implementation of VHEE-FLASH RT…
Accurate dose calculation on cone beam computed tomography (CBCT) images is essential for modern proton treatment planning workflows, particularly when accounting for inter-fractional anatomical changes in adaptive treatment scenarios.…
Purpose: This paper describes a new method to apply deep-learning algorithms for automatic segmentation of radiosensitive organs from 3D tomographic CT images before computing organ doses using a GPU-based Monte Carlo code. Methods: A deep…
Space radiation remains one of the primary hazards to spaceflight crews. The unique nature of the intravehicular radiation spectrum makes prediction of biological outcomes difficult, with computational simulation-based efforts stymied by…
We present a set of new numerical methods that are relevant to calculating radiation pressure terms in hydrodynamics calculations, with a particular focus on massive star formation. The radiation force is determined from a Monte Carlo…
The self-healing diffusion Monte Carlo algorithm (SHDMC) [Phys. Rev. B {\bf 79}, 195117 (2009), {\it ibid.} {\bf 80}, 125110 (2009)] is shown to be an accurate and robust method for calculating the ground state of atoms and molecules. By…
Background: Accurate and fast dose calculation is essential for optimizing carbon ion therapy. Existing machine learning (ML) models have been developed for other radiotherapy modalities. They use patient data with uniform CT imaging…
A new strategy for radiation therapy dosimetry planning (RTDP) used to reduce dose estimation errors due to respiratory motion in breast treatment was illustrated and evaluated in this study. On CT data set acquired for breast treatment,…
Background: In vivo dosimetry is essential for treatment verification in modern radiotherapy, but existing techniques are limited by spatiotemporal resolution and performance on non-uniform anatomy. Scintillation imaging dosimetry shows…
Targeting at the development of an accurate and efficient dose calculation engine for online adaptive radiotherapy, we have implemented a finite size pencil beam (FSPB) algorithm with a 3D-density correction method on GPU. This new…
In this study, cone-beam single projection and axial CT scans are modeled with a software package - DOCTORS, which solves the linear Boltzmann equation using the discrete ordinates method. Phantoms include a uniform 35 cm diameter water…
Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…
In radiotherapy, a trade-off exists between computational workload/speed and dose calculation accuracy. Calculation methods like pencil-beam convolution can be much faster than Monte-Carlo methods, but less accurate. The dose difference,…
Purpose: To develop a DL-based PBSPT dose prediction workflow with high accuracy and balanced complexity to support on-line adaptive proton therapy clinical decision and subsequent replanning. Methods: PBSPT plans of 103 prostate cancer…
Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…