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The human brain is a directional network system of brain regions involving directional connectivity. Seizures are a directional network phenomenon as abnormal neuronal activities start from a seizure onset zone (SOZ) and propagate to…

Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that…

神经元与认知 · 定量生物学 2016-10-07 Christian Geier , Alexander Rothkegel , Christian E. Elger , Klaus Lehnertz

Epileptic seizures are characterised by abnormal brain dynamics at multiple scales, engaging single neurons, neuronal ensembles and coarse brain regions. Key to understanding the cause of such emergent population dynamics, is capturing the…

神经元与认知 · 定量生物学 2022-12-13 Dominic RW Burrows

Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…

神经元与认知 · 定量生物学 2019-06-19 Simona Olmi , Spase Petkoski , Maxime Guye , Fabrice Bartolomei , Viktor Jirsa

Purpose: Research into epileptic networks has recently allowed deeper insights into the epileptic process. Here we investigated the importance of individual network nodes for seizure dynamics. Methods: We analysed intracranial…

神经元与认知 · 定量生物学 2014-12-03 Christian Geier , Stephan Bialonski , Christian E. Elger , Klaus Lehnertz

Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can…

信号处理 · 电气工程与系统科学 2019-11-13 Damian Pascual , Amir Aminifar , David Atienza , Philippe Ryvlin , Roger Wattenhofer

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

神经元与认知 · 定量生物学 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

Accurate prediction of epileptic seizures has remained elusive, despite the many advances in machine learning and time-series classification. In this work, we develop a convolutional network module that exploits Electroencephalogram (EEG)…

图像与视频处理 · 电气工程与系统科学 2020-07-24 Ramy Hussein , Soojin Lee , Rabab Ward , Martin J. McKeown

Epileptic seizure detection and classification in clinical electroencephalogram data still is a challenge, and only low sensitivity with a high rate of false positives has been achieved with commercially available seizure detection tools,…

信号处理 · 电气工程与系统科学 2020-07-14 Tomas Iesmantas , Robertas Alzbutas

Evidence suggests that brain network dynamics is a key determinant of brain function and dysfunction. Here we propose a new framework to assess the dynamics of brain networks based on recurrence analysis. Our framework uses recurrence plots…

神经元与认知 · 定量生物学 2020-09-17 Marinho A. Lopes , Jiaxiang Zhang , Dominik Krzemiński , Khalid Hamandi , Qi Chen , Lorenzo Livi , Naoki Masuda

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

神经元与认知 · 定量生物学 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

The performance of attractor neural networks has been shown to depend crucially on the heterogeneity of the underlying topology. We take this analysis a step further by examining the effect of degree-degree correlations -- or assortativity…

无序系统与神经网络 · 物理学 2015-05-20 Sebastiano de Franciscis , Samuel Johnson , Joaquín J. Torres

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

神经元与认知 · 定量生物学 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

Epilepsy is a neurological brain disorder which life threatening and gives rise to recurrent seizures that are unprovoked. It occurs due to the abnormal chemical changes in our brain. Over the course of many years, studies have been…

信号处理 · 电气工程与系统科学 2022-10-13 Muhammad Shoaib Farooq , Aimen Zulfiqar , Shamyla Riaz

The degree of synchronization and the amount of dynamical cluster formation in electroencephalographic (EEG) signals are characterized by employing two order parameters introduced in the context of coupled chaotic systems subject to…

混沌动力学 · 物理学 2007-05-23 M. Escalona-Moran , M. G. Cosenza , P. Guillen , P. Coutin

The brain continually reorganizes its functional network to adapt to post-stroke functional impairments. Previous studies using static modularity analysis have presented global-level behavior patterns of this network reorganization.…

统计计算 · 统计学 2024-03-25 Kaichao Wu , Beth Jelfs , Katrina Neville , Wenzhen He , Qiang Fang

Epilepsy is the fourth most common neurological disorder, affecting about 1% of the population at all ages. As many as 60% of people with epilepsy experience focal seizures which originate in a certain brain area and are limited to part of…

机器学习 · 计算机科学 2019-03-20 Diyuan Lu , Jochen Triesch

Critical dynamics are assumed to be an attractive mode for normal brain functioning as information processing and computational capabilities are found to be optimized there. Recent experimental observations of neuronal activity patterns…

神经元与认知 · 定量生物学 2015-05-28 Christian Meisel , Alexander Storch , Susanne Hallmeyer-Elgner , Ed Bullmore , Thilo Gross

Seizure and synchronization are related to each other in complex manner. Altered synchrony has been implicated in loss of consciousness during partial seizures. However, the mechanism of altered consciousness following termination of…

神经元与认知 · 定量生物学 2018-01-30 Puneet Dheer , Sandipan Pati , Srinath Jayachandran , Kaushik Kumar Majumdar