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Developing materials that can withstand the intense environments of nuclear fusion reactors is critical in developing long-term commercial viability for energy production. Tungsten is the primary candidate as a plasma facing material due to…

材料科学 · 物理学 2023-12-11 Jarod Worden , Celine Hin

Segmentation of organs or lesions from medical images plays an essential role in many clinical applications such as diagnosis and treatment planning. Though Convolutional Neural Networks (CNN) have achieved the state-of-the-art performance…

计算机视觉与模式识别 · 计算机科学 2021-05-27 Xiangde Luo , Guotai Wang , Tao Song , Jingyang Zhang , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren , Shaoting Zhang

A sensation of fullness in the bladder is a regular experience, yet the mechanisms that act to generate this sensation remain poorly understood. This is an important issue because of the clinical problems that can result when this system…

The mechanical properties of biological materials are spatially heterogeneous. Typical tissues are made up of a spanning fibrous extracellular matrix in which various inclusions, such as living cells, are embedded. While the influence of…

软凝聚态物质 · 物理学 2025-09-04 Jordan L. Shivers , Jingchen Feng , Fred C. MacKintosh

Diffusion-based and neural communication are two interesting domains in molecular communication. Both of them have distinct advantages and are exploited separately in many works. However, in some cases, neural and diffusion-based ways have…

新兴技术 · 计算机科学 2015-07-07 Peng He , Yuming Mao , Qiang Liu , Kun Yang

Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

化学物理 · 物理学 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

Artificial neural networks took a lot of inspiration from their biological counterparts in becoming our best machine perceptual systems. This work summarizes some of that history and incorporates modern theoretical neuroscience into…

神经与进化计算 · 计算机科学 2022-09-12 Robert Bain

Living cells respond to mechanical changes in the matrix surrounding them by applying contractile forces that are in turn transmitted to distant cells. We calculate the mechanical work that each cell performs in order to deform the matrix,…

软凝聚态物质 · 物理学 2021-08-17 Chaviva Sirote , Yair Shokef

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

Traditional mathematical approaches to studying analytically the dynamics of neural networks rely on the mean-field approximation, which is rigorously applicable only to networks of infinite size. However, all existing real biological…

神经元与认知 · 定量生物学 2019-04-30 Diego Fasoli , Stefano Panzeri

Neuromorphic computing uses brain-inspired principles to design circuits that can perform computational tasks with superior power efficiency to conventional computers. Approaches that use traditional electronic devices to create artificial…

应用物理 · 物理学 2020-07-14 J. Grollier , D. Querlioz , K. Y. Camsari , K. Everschor-Sitte , S. Fukami , M. D. Stiles

We analytically study membrane mediated interactions between inclusions embedded in a tubular membrane. We model inclusions as constraints coupled to the curvature tensor of the membrane tube. First, as special test cases, we analyze the…

生物物理 · 物理学 2016-09-28 Afshin Vahid , Timon Idema

The structural characterization of microgels at interfaces is fundamental to understand both their 2D phase behavior and their role as stabilizers that enable emulsions to be broken on demand. However, this characterization is usually…

Individual Neurons in the nervous systems exploit various dynamics. To capture these dynamics for single neurons, we tune the parameters of an electrophysiological model of nerve cells, to fit experimental data obtained by calcium imaging.…

定量方法 · 定量生物学 2017-11-07 Magdalena Fuchs , Manuel Zimmer , Radu Grosu , Ramin M. Hasani

Adhesion between two bodies is a key parameter in wear processes. At the macroscale, strong adhesive bonds are known to lead to high wear rates, as observed in clean metal-on-metal contact. Reducing the strength of the interfacial adhesion…

软凝聚态物质 · 物理学 2020-10-14 Enrico Milanese , Tobias Brink , Ramin Aghababaei , Jean-François Molinari

By leveraging their high mobility and small size, insects have been combined with microcontrollers to build up cyborg insects for various practical applications. Unfortunately, all current cyborg insects rely on implanted electrodes to…

机器人学 · 计算机科学 2023-03-21 Qifeng Lin , Rui Li , Feilong Zhang , Kai Kazuki , Ong Zong Chen , Xiaodong Chen , Hirotaka Sato

Manufacturing of microstructures using a microfluidic device is a largely empirical effort due to the multi-physical nature of the fabrication process. As such, models are desired that will predict microstructure performance characteristics…

计算工程、金融与科学 · 计算机科学 2024-03-05 Nicholus R. Clinkinbeard , Reza Montazami , Nicole N. Hashemi

Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human neuromodulation, with a pressing need to establish protocols that maximise neuromodulatory efficacy. In this review, we aggregate and examine…

生物物理 · 物理学 2024-07-04 Tulika Nandi , Benjamin R. Kop , Kim Butts Pauly , Charlotte J. Stagg , Lennart Verhagen

In tissue engineering, we seek to address comprehensive tissue repair and regeneration needs. Aligned nanofibers have emerged as powerful and versatile tools, attributable to their structural and biochemical congruence with the natural…

医学物理 · 物理学 2024-08-16 Gayatri Patel , Louis-S. Bouchard

Deep learning techniques have successfully been employed in numerous computer vision tasks including image segmentation. The techniques have also been applied to medical image segmentation, one of the most critical tasks in computer-aided…

计算机视觉与模式识别 · 计算机科学 2020-06-30 Titinunt Kitrungrotsakul , Iwamoto Yutaro , Lanfen Lin , Ruofeng Tong , Jingsong Li , Yen-Wei Chen