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Dual trap optical tweezers are often used in high-resolution measurements in single-molecule biophysics. Such measurements can be hindered by the presence of extraneous noise sources, the most prominent of which is the coupling of…

生物物理 · 物理学 2013-07-03 Marco Ribezzi Crivellari , Felix Ritort

Optical tweezers has emerged as a powerful tool in manipulating microscopic particles and in measuring weak forces of the order of a pico-Newton. As a result, it has found wide applications ranging from material science to biology.…

光学 · 物理学 2024-11-26 Md Arsalan Ashraf , Pramod Pullarkat

Optical tweezers are highly versatile laser traps for neutral microparticles, with fundamental applications in physics and in single molecule cell biology. Force measurements are performed by converting the stiffness response to…

光学 · 物理学 2014-06-30 R S Dutra , N B Viana , P A Maia Neto , H M Nussenzveig

Optical tweezers find applications in various fields, ranging from biology to physics. One of the fundamental steps necessary to perform quantitative measurements using trapped particles is the calibration of the tweezer's spring constant.…

量子物理 · 物理学 2020-06-05 Bruno Melo , Felipe Almeida , Guilherme Temporão , Thiago Guerreiro

We develop an optical tweezers system using a single dual-mode optical fiber where mesoscopic absorbing particles can be trapped in three dimensions and manipulated employing photophoretic forces. We generate a superposition of fundamental…

仪器与探测器 · 物理学 2017-11-22 Souvik Sil , Tushar Kanti Saha , Avinash Kumar , Sudipta K. Bera , Ayan Banerjee

Optical tweezers equipped with position detection allow for application of piconewton-scale forces and high-temporal-resolution measurements of nanometer-scale motion. While typically used for trapping microscopic objects, the optical…

An original optical tweezers using one or two chemically etched fiber nano-tips is developed. We demonstrate optical trapping of 1 micrometer polystyrene spheres at optical powers down to 2 mW. Harmonic trap potentials were found in the…

光学 · 物理学 2013-12-09 Jean-Baptiste Decombe , Serge Huant , Jochen Fick

Optical tweezers enable non-contact trapping of micro-scale objects using light. Despite their widespread use, it is currently not known how tightly it is possible to three-dimensionally trap micro-particles with a given photon budget.…

Optical tweezers (OT) have become an essential technique in several fields of physics, chemistry, and biology as precise micromanipulation tools and microscopic force transducers. Quantitative measurements require the accurate calibration…

Herein, charged microbeads handled with optical tweezers are used as a sensitive probe for simultaneous measurements of electrophoretic and dielectrophoretic forces. We first determine the electric charge carried by a single bead by keeping…

光学 · 物理学 2015-06-24 Giuseppe Pesce , Giulia Rusciano , Gianluigi Zito , Antonio Sasso

Rotational optical tweezers are used to probe the mechanical properties of unknown microsystems. Quantifying the angular trap stiffness is essential for interpreting the rotational dynamics of probe particles. While methods to determine…

The force field of optical tweezers is commonly assumed to be conservative, neglecting the complex action of the scattering force. Using a novel method that extracts local forces from trajectories of an optically trapped particle, we…

软凝聚态物质 · 物理学 2009-11-13 Pinyu Wu , Rongxin Huang , Christian Tischer , Alexandr Jonas , Ernst-Ludwig Florin

We explain and demonstrate a new method of force- and position-calibration for optical tweezers with back-focal-plane photo detection. The method combines power spectral measurements of thermal motion and the response to a sinusoidal motion…

Optical trapping, where microscopic particles are trapped and manipulated by light is a powerful and widespread technique, with the single-beam gradient trap (also known as optical tweezers) in use for a large number of biological and other…

光学 · 物理学 2007-05-23 T. A. Nieminen , H. Rubinsztein-Dunlop , N. R. Heckenberg

Optically levitated dielectric nanoparticles have become valuable tools for precision sensing and quantum optomechanical experiments. To predict the dynamic properties of a particle trapped in an optical tweezer with high fidelity, a tool…

光学 · 物理学 2024-11-20 Moosung Lee , Tobias Hanke , Sara Launer , Sungkun Hong

Optical and acoustical trapping has been established as a tool for holding and moving microscopic particles suspended in a liquid in a contact-free and non-invasive manner. Opposed to standard microscopic imaging where the probe is fixated,…

数值分析 · 数学 2025-10-27 Peter Elbau , Monika Ritsch-Marte , Otmar Scherzer , Denise Schmutz

This work presents the first optical trapping experimental demonstration of micro-particles with Frozen Waves. Frozen Waves are an efficient method to model longitudinally the intensity of non-diffracting beams obtained by superposing…

Plasmonic nano-optical tweezers enable the non-invasive manipulation of nano-objects under low illumination intensities, and have become a powerful tool for nanotechnology and biophysics. However, measuring the trap stiffness of…

光学 · 物理学 2021-02-11 Quanbo Jiang , Jean-Benoît Claude , Jérôme Wenger

Optical tweezers, with their high precision, dynamic control, and non-invasiveness, are increasingly important in scientific research and applications at the micro and nano scales. However, manipulation by optical tweezers is challenged by…

Optical trapping, also known as optical tweezing or optical levitation, is a technique that uses highly focused laser beams to manipulate micro- and nanoscopic particles. In optical traps driven by high-energy pulses, material non-linearity…

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