相关论文: Neuronal Alignment On Asymmetric Textured Surfaces
Despite differences in brain sizes and cognitive niches among mammals, their cerebral cortices posses many common features and regularities. These regularities have been a subject of experimental investigation in neuroanatomy for the last…
Abnormal cortical folding patterns may be related to neurodevelopmental disorders such as lissencephaly and polymicrogyria. In this context, computational modeling is a powerful tool to provide a better understanding of the early brain…
During division in animal cells, the actomyosin cortex has been found to exhibit counter-rotating cortical flows, also known as chiral flows, along the axis of division. Furthermore, such chiral surface flows were shown to influence…
Conceptual and mathematical models of neurons have lagged behind empirical understanding for decades. Here we extend previous work in modeling biological systems with fully scale-independent quantum information-theoretic tools to develop a…
How can dense biological tissue maintain sharp boundaries between coexisting cell populations? We explore this question within a simple vertex model for cells, focusing on the role of topology and tissue surface tension. We show that the…
The displacement of a fluid by another less viscous one in a quasi-two dimensional geometry typically leads to complex fingering patterns. In an isotropic system, dense-branching growth arises, which is characterized by repeated…
Biologically, the brain does not rely on a single type of neuron that universally functions in all aspects. Instead, it acts as a sophisticated designer of task-based neurons. In this study, we address the following question: since the…
Artificial neural networks used for reinforcement learning are structurally rigid, meaning that each optimized parameter of the network is tied to its specific placement in the network structure. It also means that a network only works with…
Computational hardware designed to mimic biological neural networks holds the promise to resolve the drastically growing global energy demand of artificial intelligence. A wide variety of hardware concepts have been proposed, and among…
Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…
Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…
This article highlights specific features of biological neurons and their dendritic trees, whose adoption may help advance artificial neural networks used in various machine learning applications. Advancements could take the form of…
Topographic maps are a brain structure connecting pre-synpatic and post-synaptic brain regions. Topographic development is dependent on Hebbian-based plasticity mechanisms working in conjunction with spontaneous patterns of neural activity…
Recent advances in memory technologies, devices and materials have shown great potential for integration into neuromorphic electronic systems. However, a significant gap remains between the development of these materials and the realization…
We consider the mechanisms by which folds, or sulci (troughs) and gyri (crests), develop in the brain. This feature, common to many gyrencephalic species including humans, has attracted recent attention from soft matter physicists. It…
The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection away from a neuron. Under normal conditions two axonal cytoskeletal polymers microtubules and neurofilaments…
This paper presents Contextual Fibre Growth (ConFiG), an approach to generate white matter numerical phantoms by mimicking natural fibre genesis. ConFiG grows fibres one-by-one, following simple rules motivated by real axonal guidance…
Neuromorphic computing is a brainlike information processing paradigm that requires adaptive learning mechanisms. A spiking neuro-evolutionary system is used for this purpose; plastic resistive memories are implemented as synapses in…
The wiring and connectivity of neurons form a structural basis for the function of the nervous system. Advances in volume electron microscopy (EM) and image segmentation have enabled mapping of circuit diagrams (connectomics) within local…
Neural systems can be modeled as networks of functionally connected neural elements. The resulting network can be analyzed using mathematical tools from network science and graph theory to quantify the system's topological organization and…