相关论文: Circadian clocks optimally adapt to sunlight for r…

The development of systemic approaches in biology has put emphasis on identifying genetic modules whose behavior can be modeled accurately so as to gain insight into their structure and function. However most gene circuits in a cell are…

A biophysical model of arousal dynamics is used to study mechanisms of synchronisation and loss of synchrony among the three key oscillators controlling sleep-wake cycles: the circadian, homeostatic, and light oscillators. Synchronisation…

Clock synchronization is a widely discussed topic in the engineering literature. Ensuring that individual clocks are closely aligned is important in network systems, since the correct timing of various events in a network is usually…

The ability of a circadian system to entrain to the 24-hour light-dark cycle is one of its most important properties. A new tool, called the entrainment map, was recently introduced to study this process for a single oscillator. Here we…

Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…

Being able to measure time, whether directly or indirectly, is a significant advantage for an organism. It permits it to predict regular events, and prepare for them on time. Thus, clocks are ubiquitous in biology. In the present paper, we…

We analyze a class of network motifs in which a short, two-node positive feed- back motif is inserted in a three-node negative feedback loop. We demonstrate that such networks can undergo a bifurcation to a state where a stable fixed point…

Circadian rhythmicity lies at the center of various important physiological and behavioral processes in mammals, such as sleep, metabolism, homeostasis, mood changes and more. It has been shown that this rhythm arises from self-sustained…

Daylight plays a major role in the wake/sleep cycle in humans. Indeed, the wake/sleep system stems from biological systems that follow a circadian rhythm determined by the light/dark alternation. The oscillations can be modeled by the…

Coupled oscillator networks underlie many biological systems, from cardiac cycles to circadian rhythms. Phase-reduced models such as the Kuramoto model have been widely used to study synchronization, but they typically assume that…

Living systems regulate many aspects of their behavior through periodic oscillations of molecular concentrations, which function as `biochemical clocks.' These clocks are intrinsically subject to thermal fluctuations, so that the duration…

We consider a periodic quantum clock based on cooperative resonance fluorescence at zero temperature. In the quantum case, this system has an exact steady state and the limit cycle appears in conditional quantum dynamics under homodyne…

A van der Pol self sustained oscillator with higher order nonlinearity exhibits a rich dynamics, with multiple periodic attractors, and still the model allows analytical approximations. Some of these properties can be conveniently exploited…

Being able to measure time, whether directly or indirectly, is a significant advantage for an organism. It allows for the timely reaction to regular or predicted events, reducing the pressure for fast processing of sensory input. Thus,…

Nearly all living organisms, including some bacterial species, exhibit biological processes with a period of about 24 h called circadian (from the Latin circa, about, dies, day) rhythms. These rhythms allow living organisms to anticipate…

Effects of synchronization in a system of two coupled oscillators with time-delayed feedback are investigated. Phase space of a system with time delay is infinite-dimensional. Thus, the picture of synchronization in such systems acquires…

We study the problem of clock synchronization in highly dynamic networks, where communication links can appear or disappear at any time. The nodes in the network are equipped with hardware clocks, but the rate of the hardware clocks can…

Spontaneous synchronization between coupled periodic systems occur in a wealth of classical physical setups. Here, we show theoretically that the phase of two distinct quantum harmonic oscillators spontaneously when they are strongly…

The production process of integrated electronic circuitry inherently leads to large heterogeneities on the component level. For electronic clock networks this implies detuned intrinsic frequencies and differences in coupling strength and…

This paper characterizes self-oscillations in discrete-time linear time-invariant (LTI) relay feedback systems with nonnegative dead zone. Specifically, we aim to establish existence criteria for unimodal self-oscillations, defined as…