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The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth,…

生物物理 · 物理学 2024-04-10 Johannes C. Krämer , Edouard Hannezo , Gerhard Gompper , Jens Elgeti

Traditional models of electrokinetic transport in porous media are based on homogenized material properties, which neglect any macroscopic effects of microscopic fluctuations. This perspective is taken not only for convenience, but also…

We study the drift of spiral waves in a simple model of heterogeneous excitable medium, having gradients in local excitability or cellular coupling. For the first time, we report the anomalous drift of spiral waves towards regions having…

斑图形成与孤子 · 物理学 2010-11-16 S. Sridhar , Sitabhra Sinha , Alexander. V. Panfilov

Ferroelectric materials are the core of common technologies, such as medical ultrasound, mobile-phone antennae and low-power memory devices. The technological interest in ferroelectrics stems from the existence of switchable mesoscale…

介观与纳米尺度物理 · 物理学 2019-04-01 Asaf Hershkovitz , Florian Johann , Maya Barzilay , Alon Hendler Avidor , Yachin Ivry

Micron-sized self-propelled (active) particles can be considered as model systems for characterizing more complex biological organisms like swimming bacteria or motile cells. We produce asymmetric microswimmers by soft lithography and study…

Spiral waves in excitable media possess both wave-like and particle-like properties. When resonantly forced (forced at the spiral rotation frequency) spiral cores travel along straight trajectories, but may reflect from medium boundaries.…

斑图形成与孤子 · 物理学 2013-04-03 Jacob Langham , Dwight Barkley

Propagation of energetic particles across the mean field direction in turbulent magnetic fields is often described as spatial diffusion. Recently, it has been suggested that initially the particles propagate systematically along meandering…

空间物理 · 物理学 2017-06-22 T. Laitinen , S. Dalla , D. Marriott

The combination of protrusions and retractions in the movement of polarized cells leads to understand the effect of possible synchronisation between the two ends of the cells. This synchronisation, in turn, could lead to different dynamics…

细胞行为 · 定量生物学 2021-09-21 Gissell Estrada-Rodriguez , Benoit Perthame

We propose a minimal mathematical model to explain long-range coordination of dynamics of multiple cells in epithelial spreading, which may be induced, under different conditions, by a chemical signal, or mechanical stress, or both. The…

生物物理 · 物理学 2009-11-30 L. M. Pismen , S. Y. Shvartsman

In seismic imaging, understanding the relationship between wavefront-propagation velocity and time-interval velocity is crucial for achieving optimal resolution. However, this task becomes even more challenging when considering anisotropic…

地球物理 · 物理学 2025-04-28 Tiago A. Coimbra , Rodrigo Bloot , Jorge H. Faccipieri

In this article, I advance the idea that physics plays a central role in cell differentiation and makes fundamental contributions to morphogenesis, revealing the totipotent nature of the zygote. Totipotency is a persistent mechanical memory…

生物物理 · 物理学 2026-03-20 Jaime Cofre

The dynamical responses of ferromagnet to the propagating electromagnetic field wave passing through it are modelled and studied here by Monte Carlo simulation in two dimensional Ising ferromagnet. Here, the electromagnetic wave is linearly…

统计力学 · 物理学 2025-08-04 Muktish Acharyya

Active diffusion of intracellular components is emerging as an important process in cell biology. This process is mediated by complex assemblies of molecular motors and cytoskeletal filaments that drive force generation in the cytoplasm and…

Chemo-mechanical waves on active deformable surfaces are a key component for many vital cellular functions. In particular, these waves play a major role in force generation and long-range signal transmission in cells that dynamically change…

Transition waves in mechanical metamaterials manifest themselves as propagating interfaces between different stable states in lattices composed of arrays of coupled, intrinsically bistable elements. Here, we show experimentally and…

应用物理 · 物理学 2026-03-11 Eleonore Duval , Giada Risso , Alex Zhang , Vincent Tournat , Katia Bertoldi

Bacterial contamination of biological conducts, catheters or water resources is a major threat to public health and can be amplified by the ability of bacteria to swim upstream. The mechanisms of this rheotaxis, the reorientation with…

软凝聚态物质 · 物理学 2019-08-12 Arnold Mathijssen , Nuris Figueroa-Morales , Gaspard Junot , Eric Clement , Anke Lindner , Andreas Zöttl

We describe a general mechanism of controllable energy exchange between waves propagating in a dynamic artificial crystal. We show that if a spatial periodicity is temporarily imposed on the transmission properties of a wave-carrying medium…

Growth drives cellular dynamics in dense aggregates including bacterial colonies, developing tissues, and tumors. We investigate the underlying physical principles emerging from the interplay of growth, steric repulsion, and motility in a…

软凝聚态物质 · 物理学 2025-02-11 Torben Sunkel , Lukas Hupe , Philip Bittihn

Inertial waves propagate in homogeneous rotating fluids, and constitute a challenging and simplified case study for the broader class of inertio-gravity waves, present in all geophysical and astrophysical media, and responsible for…

流体动力学 · 物理学 2014-02-12 Anna Rabitti , Leo R. M. Maas

Pulsatory activity patterns, driven by mechanochemical feedback, are prevalent in many biological systems. Here we present a theoretical framework to elucidate the mechanical origin and regulation of pulsatile activity patterns within…

生物物理 · 物理学 2023-10-10 Fernanda Pérez-Verdugo , Samuel Banks , Shiladitya Banerjee