相关论文: Quantifying stretching and rearrangement in epithe…
We perform extensive simulations of a 2D LJ glass subjected to quasi-static shear deformation at T=0. We analyze the distribution of non-affine displacements in terms of contributions of plastic, irreversible events, and elastic, reversible…
We report experiments on the deformation and transport of an elastic fiber in a viscous cellular flow, namely a lattice of counter-rotative vortices. We show that the fiber can buckle when approaching a stagnation point. By tuning either…
Epithelial cell clusters often move collectively on a substrate. Mechanical signals play a major role in organizing this behavior. There are a number of experimental observations in these systems which await a comprehensive explanation.…
The two-phase composite approach of Estrin et al. (1998) describes an evolving dislocation cell structure. Mckenzie et al. (2007) enhanced the model to capture the effects of hydrostatic pressure and temperature during severe plastic…
The dynamics of single cell migration on flat surfaces is usually modeled by a Langevin-like problem consisting of ballistic motion for short periods and random walk. for long periods. Conversely, recent studies have revealed a previously…
Collective cell migration plays a crucial role in numerous biological processes, including tumour growth, wound healing, and the immune response. Often, the migrating population consists of cells with various different phenotypes. This…
We have recorded the swarming-like collective migration of a large number of keratocytes (tissue cells obtained from the scales of goldfish) using long-term videomicroscopy. By increasing the overall density of the migrating cells, we have…
Like a cr\^epe resting on a plate, a thin elastic sheet can fold smoothly under its own weight, forming reversible shapes without creases or imposed hinges. Such soft folds arise from a balance between elastic bending and gravity, yet their…
Cell motility in dense cell collectives is pivotal in various diseases like cancer metastasis and asthma. A central aspect in these phenomena is the heterogeneity in cell motility, but identifying the motility of individual cells is…
Quantifying the in-plane rheology of epithelial monolayers remains challenging due to the difficulty of imposing controlled shear. We introduce a self-driven, rheometer-like assay in which collective migration generates stationary shear…
We consider a model of fragmentation of sheet by cracks that move with a velocity in preferred direction, but undergo random transverse displacements as they move. There is a non-zero probability of crack-splitting, and the split cracks…
Liquid migration in active soft solids is a very common phenomenon in Nature at different scales: from cells to leaves. It can be caused by mechanical as well as chemical actions. The work focuses on the migration of liquid provoked by…
Collective cell movement, characterized by multiple cells that are in contact for substantial periods of time and undergo correlated motion, plays a central role in cancer and embryogenesis. Recent imaging experiments have provided…
A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governed by motor molecule activity, which does not depend on…
The collective chemotaxis of multicellular clusters is an important phenomenon in various physiological contexts, ranging from embryonic development to cancer metastasis. Such clusters often display interesting shape dynamics and…
Movement of cell clusters along extracellular matrices (ECM) during tissue development, wound healing, and early stage of cancer invasion involve various inter-connected migration modes such as: (1) cell movement within clusters, (2)…
Biological adhesion is a critical mechanical function of complex organisms operating at multiple scales. At the cellular scale, cell-cell adhesion is remarkably tunable to enable both cohesion and malleability during development,…
We present a numerical study of a thin elastic sheet with small extensibility freely sedimenting in a viscous fluid. Two scenarios are investigated: sedimentation in free space and near an infinite wall, where the wall may be vertical or…
To understand cell migration, it is crucial to gain knowledge on how cells exert and integrate forces on/from their environment. A quantity of prime interest for biophysicists interested in cell movements modeling is the intracellular…
We provide a minimal continuum model for mesoscale plasticity, explaining the cellular dislocation structures observed in deformed crystals. Our dislocation density tensor evolves from random, smooth initial conditions to form self-similar…