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The development of complex multicellular organisms from a single parent cell is a highly orchestrated process that cells conduct collectively without central guidance, creating intricate dynamic patterns essential for development and…

软凝聚态物质 · 物理学 2025-05-29 Siavash Monfared , Aleksandra Ardaševa , Amin Doostmohammadi

The mechanical problem discussed in this paper focuses on the stress state estimation in a composite laminate in the vicinity of a free edge or microcracks. To calculate these stresses, we use two models called Multiparticle Models of…

经典物理 · 物理学 2009-07-07 Rui Pedro Carreira , Jean-François Caron , Alberto Diaz Diaz

Scale-free networks play a fundamental role in the study of complex networks and various applied fields due to their ability to model a wide range of real-world systems. A key characteristic of these networks is their degree distribution,…

物理与社会 · 物理学 2025-01-14 Nixon Jerez-Lillo , Francisco A. Rodrigues , Paulo H. Ferreira , Pedro L. Ramos

The new method is proposed to monitor the level of current physical load and accumulated fatigue by several objective and subjective characteristics. It was applied to the dataset targeted to estimate the physical load and fatigue by…

计算机与社会 · 计算机科学 2018-01-19 Yuri Gordienko , Sergii Stirenko , Yuriy Kochura , Oleg Alienin , Michail Novotarskiy , Nikita Gordienko

The study is devoted to geometrically non-linear modelling of viscoplastic structures with residual stresses. We advocate and develop a special approach to residual stresses based on the transition between reference configurations. The…

材料科学 · 物理学 2021-04-06 I. I. Tagiltsev , A. V. Shutov

Using a popular vertex-based model to describe a spatially disordered planar epithelial monolayer, we examine the relationship between cell shape and mechanical stress at the cell and tissue level. Deriving expressions for stress tensors…

细胞行为 · 定量生物学 2017-08-14 Alexander Nestor-Bergmann , Georgina Goddard , Sarah Woolner , Oliver Jensen

Recently proposed formulation of the Boundary Element Method for adhesive contacts has been generalized for contacts of functionally graded materials with and without adhesion. First, proceeding from the fundamental solution for single…

软凝聚态物质 · 物理学 2016-12-28 Qiang Li , Valentin L. Popov

The vertex model is a popular framework for modelling tightly packed biological cells, such as confluent epithelia. Cells are described by convex polygons tiling the plane and their equilibrium is found by minimizing a global mechanical…

生物物理 · 物理学 2021-03-17 Oliver E. Jensen , Emma Johns , Sarah Woolner

An efficient and reliable stress computation algorithm is presented, which is based on implicit integration of the local evolution equations of multiplicative finite-strain plasticity/viscoplasticity. The algorithm is illustrated by an…

数值分析 · 数学 2016-05-25 A. V. Shutov

Epithelial tissues are driven out of thermodynamic equilibrium by internally generated forces, causing complex patterns of motion. Even when both the forces and motion are measurable, it is not yet possible to relate the two, because the…

生物物理 · 物理学 2025-11-18 Molly McCord , Jacob Notbohm

Effective connectivity analysis provides an understanding of the functional organization of the brain by studying how activated regions influence one other. We propose a nonparametric Bayesian approach to model effective connectivity…

应用统计 · 统计学 2011-07-22 Sourabh Bhattacharya , Ranjan Maitra

Causal inference has gained much popularity in recent years, with interests ranging from academic, to industrial, to educational, and all in between. Concurrently, the study and usage of neural networks has also grown profoundly (albeit at…

机器学习 · 统计学 2024-05-07 Demetrios Papakostas , Andrew Herren , P. Richard Hahn , Francisco Castillo

Recent developments in wearable sensors demonstrate promising results for monitoring physiological status in effective and comfortable ways. One major challenge of physiological status assessment is the problem of transfer learning caused…

信号处理 · 电气工程与系统科学 2020-04-20 Mo Han , Ozan Ozdenizci , Ye Wang , Toshiaki Koike-Akino , Deniz Erdogmus

Quantifying the influence of infinitesimal changes in training data on model performance is crucial for understanding and improving machine learning models. In this work, we reformulate this problem as a weighted empirical risk minimization…

机器学习 · 计算机科学 2025-04-11 Omri Lev , Ashia C. Wilson

The immersed boundary method is a mathematical formulation and numerical method for solving fluid-structure interaction problems. For many biological problems, such as models that include the cell membrane, the immersed structure is a…

数值分析 · 数学 2018-06-07 Ondrej Maxian , Andrew T. Kassen , Wanda Strychalski

Estimating causal effects is particularly challenging when outcomes arise in complex, non-Euclidean spaces, where conventional methods often fail to capture meaningful structural variation. We develop a framework for topological causal…

统计方法学 · 统计学 2026-03-04 Kwangho Kim , Hajin Lee

We show that in experimental atomic force microscopy studies of the lifetime distribution of mechanically stressed folded proteins the effects of externally applied fluctuations can not be distinguished from those of internally present…

生物物理 · 物理学 2011-10-21 Maxime Clusel , Eric I. Corwin

This paper presents a numerical investigation of Turing patterns (TPs) utilizing the reaction-diffusion equation for the activator $u$ and the inhibitor $v$ on two- and three-dimensional lattices, discarding vertex fluctuations. The absence…

斑图形成与孤子 · 物理学 2026-04-30 Fumitake Kato , Hiroshi Koibuchi , Madoka Nakayama , Sohei Tasaki , Tetsuya Uchimoto

Network inference has been extensively studied in several fields, such as systems biology and social sciences. Learning network topology and internal dynamics is essential to understand mechanisms of complex systems. In particular, sparse…

机器学习 · 统计学 2022-06-13 Yasen Wang , Junyang Jin , Jorge Goncalves

Tendon-bone enthesis connects tendon and bone, two mechanically dissimilar materials, while effectively minimizing stress concentrations, a capability rarely achieved in engineering materials. Its hierarchical organization and graded…

软凝聚态物质 · 物理学 2026-04-14 Zhangke Yang , Zhaoxu Meng
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