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Dynamic optical coherence tomography (DOCT) statistically analyzes fluctuations in time-sequential OCT signals, enabling label-free and three-dimensional visualization of intratissue and intracellular activities. Current DOCT methods, such…

In OCT angiography (OCTA), decorrelation computation has been widely used as a local motion index to identify dynamic flow from static tissues, but its dependence on SNR severely degrades the vascular visibility, particularly in low- SNR…

医学物理 · 物理学 2019-04-16 Luzhe Huang , Yiming Fu , Ruixiang Chen , Shanshan Yang , Haixia Qiu , Xining Wu , Shiyong Zhao , Ying Gu , Peng Li

Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…

医学物理 · 物理学 2024-02-23 Leopold Veselka , Lisa Krainz , Leonidas Mindrinos , Wolfgang Drexler , Peter Elbau

Traveling-wave optical coherence elastography (OCE) is a promising technique to measure the stiffness of biological tissues. While OCE has been applied to relatively homogeneous samples, tissues with significantly varying elasticity through…

医学物理 · 物理学 2022-01-31 Xu Feng , Guo-Yang Li , Antoine Ramier , Amira M. Eltony , Seok-Hyun Yun

Understanding stress-strain relationships in arteries is important for fundamental investigations in mechanobiology. Here we demonstrate the essential role of chemoelasticity in determining the mechanical properties of arterial tissues.…

In x-ray computed tomography (CT) it is generally acknowledged that reconstruction methods exploiting image sparsity allow reconstruction from a significantly reduced number of projections. The use of such reconstruction methods is…

数值分析 · 数学 2014-08-05 Jakob S. Jørgensen , Emil Y. Sidky , Per Christian Hansen , Xiaochuan Pan

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

数值分析 · 数学 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Calibration is crucial in deep learning applications, especially in fields like healthcare and autonomous driving, where accurate confidence estimates are vital for decision-making. However, deep neural networks often suffer from…

机器学习 · 计算机科学 2024-10-17 Linwei Tao , Haolan Guo , Minjing Dong , Chang Xu

Understanding corneal stiffness is valuable for improving refractive surgery, detecting corneal abnormalities, and assessing intraocular pressure. However, accurately measuring the elastic properties, particularly the tensile and shear…

医学物理 · 物理学 2023-08-11 Guo-Yang Li , Xu Feng , Seok-Hyun Yun

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and…

医学物理 · 物理学 2019-07-02 Cerine Lal , Hrebesh M Subhash , Sergey Alexandrov , Martin J Leahy

Clinical tracking systems are popular but typically require specific tracking markers. During the last years, scanning speed of optical coherence tomography (OCT) has increased to A-scan rates above 1 MHz allowing to acquire volume scans of…

We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…

Multiexponential modeling of relaxation or diffusion MR signal decays is a popular approach for estimating and spatially mapping different microstructural tissue compartments. While this approach can be quite powerful, it is also limited by…

图像与视频处理 · 电气工程与系统科学 2019-05-10 Daeun Kim , Jessica L. Wisnowski , Christopher T. Nguyen , Justin P. Haldar

Correlations between factors of variation are prevalent in real-world data. Exploiting such correlations may increase predictive performance on noisy data; however, often correlations are not robust (e.g., they may change between domains,…

机器学习 · 计算机科学 2022-12-26 Christina M. Funke , Paul Vicol , Kuan-Chieh Wang , Matthias Kümmerer , Richard Zemel , Matthias Bethge

This dissertation relates to the transition of the state of the art of swept source optical coherence tomography (SS-OCT) systems to a new realm in which the image acquisition speed is improved by an order of magnitude. With the aid of a…

图像与视频处理 · 电气工程与系统科学 2020-02-21 Amir Tofighi Zavareh

Rapid mapping of the mechanical properties of soft biological tissues from light microscopy to macroscopic imaging could transform fundamental biophysical research by providing clinical biomarkers to complement in vivo elastography. We here…

Objective: Strain elastography and shear wave elastography are two commonly used methods to quantify cervical elasticity; however, they have limitations. Strain elastography is effective in showing tissue elasticity distribution in a single…

Most robot mapping techniques for lidar sensors tessellate the environment into pixels or voxels and assume uniformity of the environment within them. Although intuitive, this representation entails disadvantages: The resulting grid maps…

计算机视觉与模式识别 · 计算机科学 2019-10-25 Alexander Schaefer , Lukas Luft , Wolfram Burgard

Model-based computational elasticity imaging of tissues can be posed as solving an inverse problem over finite elements spanning the displacement image. As most existing quasi-static elastography methods count on deterministic formulations…

图像与视频处理 · 电气工程与系统科学 2020-10-22 Narges Mohammadi , Marvin M. Doyley , Mujdat Cetin

Background: Recent studies have indicated that functional connectivity is dynamic even during rest. A common approach to modeling the dynamic functional connectivity in whole-brain resting-state fMRI is to compute the correlation between…

神经元与认知 · 定量生物学 2019-11-05 Shih-Gu Huang , S. Balqis Samdin , Chee-Ming Ting , Hernando Ombao , Moo K. Chung