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Whether, when, and how causal interactions between neurons can be meaningfully studied from observations of neural activity alone are vital questions in neural data analysis. Here we aim to better outline the concept of functional…

神经元与认知 · 定量生物学 2023-12-05 Ian H. Stevenson

We consider a threshold-crossing spiking process as a simple model for the activity within a population of neurons. Assuming that these neurons are driven by a common fluctuating input with Gaussian statistics, we evaluate the…

神经元与认知 · 定量生物学 2009-06-11 Yoram Burak , Sam Lewallen , Haim Sompolinsky

The action potential constitutes the digital component of the signaling dynamics of neurons. But the biophysical nature of the full-time course of the action potential associated with changes in membrane potential is mathematically distinct…

神经元与认知 · 定量生物学 2026-04-16 Gabriel A. Silva

The presence of correlated noise, arising from a mixture of independent fluctuations and a common noisy input shared across the neural population, is a ubiquitous feature of neural circuits, yet its impact on collective network dynamics…

神经元与认知 · 定量生物学 2026-01-16 Hui Wang , Chunming Zheng

Analytical expressions are put forward to investigate the forced spiking activity of abstract neuron models such as the driven leaky integrate-and-fire (LIF) model. The method is valid in a wide parameter regime beyond the restraining…

神经元与认知 · 定量生物学 2007-05-23 Michael Schindler , Peter Talkner , Peter Hänggi

The highly variable dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference but stand in apparent contrast to the deterministic response of neurons measured in vitro.…

神经元与认知 · 定量生物学 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

Statistical properties of spike trains measured from a sensory neuron in-vivo are studied experimentally and theoretically. Experiments are performed on an identified neuron in the visual system of the blowfly. It is shown that the spike…

生物物理 · 物理学 2007-05-23 N. Brenner , O. Agam , W. Bialek , R. de Ruyter van Steveninck

In neural systems, synaptic plasticity is usually driven by spike trains. Due to the inherent noises of neurons, synapses and networks, spike trains typically exhibit externally uncontrollable variability such as spatial heterogeneity and…

神经元与认知 · 定量生物学 2015-06-18 Zedong Bi , Changsong Zhou , Hai-Jun Zhou

Stochastic integrate-and-fire (IF) neuron models have found widespread applications in computational neuroscience. Here we present results on the white-noise-driven perfect, leaky, and quadratic IF models, focusing on the spectral…

神经元与认知 · 定量生物学 2015-05-14 Rafael D. Vilela , Benjamin Lindner

Chemical and electrical synapses shape the dynamics of neuronal networks. Numerous theoretical studies have investigated how each of these types of synapses contributes to the generation of neuronal oscillations, but their combined effect…

适应与自组织系统 · 物理学 2019-10-30 Bastian Pietras , Federico Devalle , Alex Roxin , Andreas Daffertshofer , Ernest Montbrió

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

统计理论 · 数学 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing…

神经元与认知 · 定量生物学 2011-09-23 Chun-Chung Chen , David Jasnow

The neural dynamics generating sensory, motor, and cognitive functions are commonly understood through field theories for neural population activity. Classic neural field theories are derived from highly simplified models of individual…

神经元与认知 · 定量生物学 2023-11-21 Gabriel Koch Ocker

We present a method to estimate Gibbs distributions with \textit{spatio-temporal} constraints on spike trains statistics. We apply this method to spike trains recorded from ganglion cells of the salamander retina, in response to natural…

神经元与认知 · 定量生物学 2013-01-11 J. C. Vasquez , O. Marre , A. G. Palacios , M. J. Berry , B. Cessac

We study the stochastic dynamics of strongly-coupled excitable elements on a tree network. The peripheral nodes receive independent random inputs which may induce large spiking events propagating through the branches of the tree and leading…

生物物理 · 物理学 2017-07-14 Justus Kromer , Ali Khaledi-Nasab , Lutz Schimansky-Geier , Alexander B. Neiman

Correlations in spike-train ensembles can seriously impair the encoding of information by their spatio-temporal structure. An inevitable source of correlation in finite neural networks is common presynaptic input to pairs of neurons. Recent…

神经元与认知 · 定量生物学 2015-06-04 Tom Tetzlaff , Moritz Helias , Gaute T. Einevoll , Markus Diesmann

The synaptic connectivity of cortex is plastic, with experience shaping the ongoing interactions between neurons. Theoretical studies of spike timing-dependent plasticity (STDP) have focused on either just pairs of neurons or large-scale…

神经元与认知 · 定量生物学 2016-08-02 Gabriel Koch Ocker , Brent Doiron

We present two Bayesian procedures to infer the interactions and external currents in an assembly of stochastic integrate-and-fire neurons from the recording of their spiking activity. The first procedure is based on the exact calculation…

机器学习 · 统计学 2011-02-28 Remi Monasson , Simona Cocco

Sampling considerations limit the experimental conditions under which information theoretic analyses of neurophysiological data yield reliable results. We develop a procedure for computing the full temporal entropy and information of…

生物物理 · 物理学 2009-11-06 Simon R. Schultz , Stefano Panzeri

We study the collective dynamics of a Leaky Integrate and Fire network in which precise relative phase relationship of spikes among neurons are stored, as attractors of the dynamics, and selectively replayed at differentctime scales. Using…

神经元与认知 · 定量生物学 2012-10-26 Silvia Scarpetta , Ferdinando Giacco