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Advances in survival analysis have facilitated unprecedented flexibility in data modeling, yet there remains a lack of tools for graphically illustrating the influence of continuous covariates on predicted survival outcomes. We propose the…

应用统计 · 统计学 2024-01-15 Yushu Shi , Liangliang Zhang , Kim-Anh Do , Robert R. Jenq , Christine B. Peterson

Population structure can be modelled by evolutionary graphs, which can have a substantial, but very subtle influence on the fate of the arising mutants. Individuals are located on the nodes of these graphs, competing with each other to…

种群与进化 · 定量生物学 2018-10-31 Marius Möller , Laura Hindersin , Arne Traulsen

In this paper, we develop a general theory for the estimation of the transition probabilities of reversible Markov chains using the maximum entropy principle. A broad range of physical models can be studied within this approach. We use…

统计力学 · 物理学 2015-05-14 Erik Van der Straeten

Recent literature has found conditional transition rates to be a useful tool for avoiding Markov assumptions in multi-state models. While the estimation of univariate conditional transition rates has been extensively studied, the…

统计理论 · 数学 2024-08-30 Theis Bathke

Reinforced processes are known to provide a stochastic representation for the quasi-stationary distribution of a given killed Markov process - describing the killed Markov process at fixed time instants. In this paper we shall adapt the…

概率论 · 数学 2022-02-10 Oliver Tough

Markov branching systems form a fundamental class of stochastic models that are extensively applied in biology, physics, finance, and other domains. These systems are distinguished by their continuous-time evolution and inherent branching…

We introduce a new method for predicting the formation of links in real-world networks, which we refer to as the method of effective transitions. This method relies on the theory of isospectral matrix reductions to compute the probability…

社会与信息网络 · 计算机科学 2019-09-04 Bryn Balls-Barker , Benjamin Webb

By generating the specifics of a network structure only when needed (on-the-fly), we derive a simple stochastic process that exactly models the time evolution of susceptible-infectious dynamics on finite-size networks. The small number of…

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

计算机视觉与模式识别 · 计算机科学 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Survival models are used to analyze time-to-event data in a variety of disciplines. Proportional hazard models provide interpretable parameter estimates, but proportional hazards assumptions are not always appropriate. Non-parametric models…

统计方法学 · 统计学 2022-07-08 Richard D. Payne , Nilabja Guha , Bani K. Mallick

Decomposable graphs are known for their tedious and complicated Markov update steps. Instead of modelling them directly, this work introduces a class of tree-dependent bipartite graphs that span the projective space of decomposable graphs.…

统计方法学 · 统计学 2017-10-11 Mohamad Elmasri

In this paper we present the Markov variation, a smoothness measure which offers a probabilistic interpretation of graph signal smoothness. This measure is then used to develop an optimization framework for graph signal interpolation. Our…

信号处理 · 电气工程与系统科学 2020-01-29 Ayelet Heimowitz , Yonina C. Eldar

Diagonalizability plays an important role in the analysis and design of multivariable systems. A structured matrix is called structurally diagonalizable if almost all of its numerical realizations, obtained by assigning real values to its…

最优化与控制 · 数学 2026-01-30 Yuan Zhang , Yutong Han , Yuanqing Xia , Aming Li

Direct simulation of biomolecular dynamics in thermal equilibrium is challenging due to the metastable nature of conformation dynamics and the computational cost of molecular dynamics. Biased or enhanced sampling methods may improve the…

化学物理 · 物理学 2015-06-12 Benjamin Trendelkamp-Schroer , Frank Noe

When analyzing weighted networks using spectral embedding, a judicious transformation of the edge weights may produce better results. To formalize this idea, we consider the asymptotic behavior of spectral embedding for different…

机器学习 · 统计学 2023-01-23 Ian Gallagher , Andrew Jones , Anna Bertiger , Carey Priebe , Patrick Rubin-Delanchy

We analyze the properties of degree-preserving Markov chains based on elementary edge switchings in undirected and directed graphs. We give exact yet simple formulas for the mobility of a graph (the number of possible moves) in terms of its…

无序系统与神经网络 · 物理学 2012-03-12 E. S. Roberts , A. Annibale , A. C. C. Coolen

We present the probability preserving description of the decaying particle within the framework of quantum mechanics of open systems taking into account the superselection rule prohibiting the superposition of the particle and vacuum. In…

量子物理 · 物理学 2007-05-23 P. Caban , J. Rembielinski , K. A. Smolinski , Z. Walczak

This work presents a construction of stationary Markov models with negative-binomial marginal distributions. A simple closed form expression for the corresponding transition probabilities is given, linking the proposal to well-known classes…

统计方法学 · 统计学 2019-04-10 Fabrizio Leisen , Ramsés H. Mena , Freddy Palma Mancilla , Luca Rossini

In this paper, we explore a method for treating survival analysis as a classification problem. The method uses a "stacking" idea that collects the features and outcomes of the survival data in a large data frame, and then treats it as a…

统计方法学 · 统计学 2019-09-27 Chenyang Zhong , Robert Tibshirani

Evolutionary graph theory studies the evolutionary dynamics of populations structured on graphs. A central problem is determining the probability that a small number of mutants overtake a population. Currently, Monte Carlo simulations are…

计算机科学与博弈论 · 计算机科学 2013-01-14 Paulo Shakarian , Patrick Roos , Geoffrey Moores