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The ordinary least squares estimate in linear regression is sensitive to the influence of errors with large variance, which reduces its robustness, especially when dealing with heavy-tailed errors or outliers frequently encountered in…

统计方法学 · 统计学 2025-05-01 Mengjiao Shi , Yunhai Xiao

Graph theoretical analyses have become standard tools in modeling functional and anatomical connectivity in the brain. With the advent of connectomics, the primary graphs or networks of interest are structural connectome (derived from DTI…

神经元与认知 · 定量生物学 2022-07-07 Carlo Amodeo , Igor Fortel , Olusola Ajilore , Liang Zhan , Alex Leow , Theja Tulabandhula

We study the problem of modeling multiple symmetric, weighted networks defined on a common set of nodes, where networks arise from different groups or conditions. We propose a model in which each network is expressed as the sum of a shared…

统计理论 · 数学 2025-06-23 Hao Yan , Keith Levin

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

计算机视觉与模式识别 · 计算机科学 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

Functional connections in the brain are frequently represented by weighted networks, with nodes representing locations in the brain, and edges representing the strength of connectivity between these locations. One challenge in analyzing…

应用统计 · 统计学 2022-09-28 Yura Kim , Daniel Kessler , Elizaveta Levina

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

机器学习 · 计算机科学 2025-03-20 Chenyu Liu , Luca Rossi

It is of great significance to apply deep learning for the early diagnosis of Alzheimer's Disease (AD). In this work, a novel tensorizing GAN with high-order pooling is proposed to assess Mild Cognitive Impairment (MCI) and AD. By…

机器学习 · 计算机科学 2020-08-04 Wen Yu , Baiying Lei , Michael K. Ng , Albert C. Cheung , Yanyan Shen , Shuqiang Wang

We provide a review and a comparison of methods for differential network estimation in Gaussian graphical models with focus on structure learning. We consider the case of two datasets from distributions associated with two graphical models.…

统计方法学 · 统计学 2025-03-07 Anna Plaksienko , Magne Thoresen , Vera Djordjilović

In this paper, we studied the association between the change of structural brain volumes to the potential development of Alzheimer's disease (AD). Using a simple abstraction technique, we converted regional cortical and subcortical volume…

图像与视频处理 · 电气工程与系统科学 2019-05-16 Rui Zhang , Luca Giancardo , Danilo A. Pena , Yejin Kim , Hanghang Tong , Xiaoqian Jiang

Alzheimer's disease is the most common dementia leading to an irreversible neurodegenerative process. To date, subject revealed advanced brain structural alterations when the diagnosis is established. Therefore, an earlier diagnosis of this…

计算机视觉与模式识别 · 计算机科学 2018-07-10 Kilian Hett , Vinh-Thong Ta , Jose Vicente Manjon , Pierrick Coupé

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

图像与视频处理 · 电气工程与系统科学 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

神经元与认知 · 定量生物学 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang

The focus of this paper is two fold. Firstly, we present a logical approach to graph modification problems such as minimum node deletion, edge deletion, edge augmentation problems by expressing them as an expression in first order (FO)…

计算机科学中的逻辑 · 计算机科学 2017-11-09 Kona Harshita , Sounaka Mishra , Renjith. P , N. Sadagopan

We model time-varying network data as realizations from multivariate Gaussian distributions with precision matrices that change over time. To facilitate parameter estimation, we require not only that each precision matrix at any given time…

统计方法学 · 统计学 2022-03-11 Jie Jian , Peijun Sang , Mu Zhu

Brain networks has attracted the interests of many neuroscientists. From functional MRI (fMRI) data, statistical tools have been developed to recover brain networks. However, the dimensionality of whole-brain fMRI, usually in hundreds of…

统计方法学 · 统计学 2014-04-08 Xi Luo

Graphical models have been used extensively for modeling brain connectivity networks. However, unmeasured confounders and correlations among measurements are often overlooked during model fitting, which may lead to spurious scientific…

统计方法学 · 统计学 2020-12-10 Yanxin Jin , Yang Ning , Kean Ming Tan

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

计算机视觉与模式识别 · 计算机科学 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…

图像与视频处理 · 电气工程与系统科学 2025-03-04 Yexiao He , Ziyao Wang , Yuning Zhang , Tingting Dan , Tianlong Chen , Guorong Wu , Ang Li

Brain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a common brain disorder that causes memory loss…

图像与视频处理 · 电气工程与系统科学 2024-03-11 Maleka Khatun , Md Manowarul Islam , Habibur Rahman Rifat , Md. Shamim Bin Shahid , Md. Alamin Talukder , Md Ashraf Uddin

We consider the problem of estimating the topology of multiple networks from nodal observations, where these networks are assumed to be drawn from the same (unknown) random graph model. We adopt a graphon as our random graph model, which is…

机器学习 · 统计学 2022-02-14 Madeline Navarro , Santiago Segarra