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The last decade has seen the advent and consolidation of ontology based tools for the identification and biological interpretation of classes of genes, such as the Gene Ontology. The information accumulated time-by-time and included in the…

分子网络 · 定量生物学 2021-08-25 Salvatore Miccichè

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

基因组学 · 定量生物学 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Nowadays genetic algorithm (GA) is greatly used in engineering pedagogy as an adaptive technique to learn and solve complex problems and issues. It is a meta-heuristic approach that is used to solve hybrid computation challenges. GA…

其他计算机科学 · 计算机科学 2020-07-27 Tanweer Alam , Shamimul Qamar , Amit Dixit , Mohamed Benaida

Many statistical problems involve optimization over a discrete parameter space having an unknown dimension. In such settings, gradient-based methods often fail due to the non-differentiability of the objective function or a non-convex or…

应用统计 · 统计学 2026-03-19 Mo Li , QiQi Lu , Robert Lund , Xueheng Shi

Many problems within personalized medicine and digital health rely on the analysis of continuous-time functional biomarkers and other complex data structures emerging from high-resolution patient monitoring. In this context, this work…

机器学习 · 统计学 2025-01-14 Marcos Matabuena

Markov State Models (MSMs) are a powerful framework to reproduce the long-time conformational dynamics of biomolecules using a set of short Molecular Dynamics (MD) simulations. However, precise kinetics predictions of MSMs heavily rely on…

生物大分子 · 定量生物学 2018-06-27 Qihua Chen , Jiangyan Feng , Shriyaa Mittal , Diwakar Shukla

Designing safe and sustainable chemicals is critical to combat chemical pollution in our environment. Machine learning (ML) methods have been developed to aid with de novo molecule design. However, data on the environmental impacts of…

人机交互 · 计算机科学 2026-05-18 Coelina Robinson , Franziska Weissbach , Kjell Jorner , Mennatallah El-Assady , Christina Humer

Over the last decade, wireless networks have experienced an impressive growth and now play a main role in many telecommunications systems. As a consequence, scarce radio resources, such as frequencies, became congested and the need for…

最优化与控制 · 数学 2017-04-19 Fabio D'Andreagiovanni

Foundation models (FMs) have exhibited remarkable performance across a wide range of downstream tasks in many domains. Nevertheless, general-purpose FMs often face challenges when confronted with domain-specific problems, due to their…

计算工程、金融与科学 · 计算机科学 2023-08-22 Yizhen Luo , Jiahuan Zhang , Siqi Fan , Kai Yang , Yushuai Wu , Mu Qiao , Zaiqing Nie

Genetic Algorithms have established their capability for solving many complex optimization problems. Even as good solutions are produced, the user's understanding of a problem is not necessarily improved, which can lead to a lack of…

神经与进化计算 · 计算机科学 2024-07-10 GianCarlo Catalano , Alexander E. I. Brownlee , David Cairns , John McCall , Russell Ainslie

The focus of these lecture notes is on abstract models and basic ideas and results that relate to the operational semantics of programming languages largely conceived. The approach is to start with an abstract description of the computation…

编程语言 · 计算机科学 2025-10-15 Roberto M. Amadio

The use of semantic features can improve the efficiency of target search in unknown environments for robotic search and rescue missions. Current target search methods rely on training with large datasets of similar domains, which limits the…

机器人学 · 计算机科学 2026-04-01 Max Lodel , Nils Wilde , Robert Babuška , Javier Alonso-Mora

Symbolic regression is a task aimed at identifying patterns in data and representing them through mathematical expressions, generally involving skeleton prediction and constant optimization. Many methods have achieved some success, however…

机器学习 · 计算机科学 2024-08-16 Yusong Deng , Min Wu , Lina Yu , Jingyi Liu , Shu Wei , Yanjie Li , Weijun Li

Genetic fitness optimization using small populations or small population updates across generations generally suffers from randomly diverging evolutions. We propose a notion of highly probable fitness optimization through feasible…

神经与进化计算 · 计算机科学 2007-05-23 Paul Vitanyi

In this article we provide a comprehensive review of the different evolutionary algorithm techniques used to address multimodal optimization problems, classifying them according to the nature of their approach. On the one hand there are…

神经与进化计算 · 计算机科学 2015-08-24 Noe Casas

Semantic occupancy prediction aims to infer dense geometry and semantics of surroundings for an autonomous agent to operate safely in the 3D environment. Existing occupancy prediction methods are almost entirely trained on human-annotated…

计算机视觉与模式识别 · 计算机科学 2023-06-16 Zhiyu Tan , Zichao Dong , Cheng Zhang , Weikun Zhang , Hang Ji , Hao Li

In this work, we present Semantic Gesticulator, a novel framework designed to synthesize realistic gestures accompanying speech with strong semantic correspondence. Semantically meaningful gestures are crucial for effective non-verbal…

图形学 · 计算机科学 2025-10-23 Zeyi Zhang , Tenglong Ao , Yuyao Zhang , Qingzhe Gao , Chuan Lin , Baoquan Chen , Libin Liu

The prediction of molecular properties is a crucial task in the field of material and drug discovery. The potential benefits of using deep learning techniques are reflected in the wealth of recent literature. Still, these techniques are…

机器学习 · 计算机科学 2023-09-06 Minghao Guo , Veronika Thost , Samuel W Song , Adithya Balachandran , Payel Das , Jie Chen , Wojciech Matusik

Autonomous robots can benefit greatly from human-provided semantic characterizations of uncertain task environments and states. However, the development of integrated strategies which let robots model, communicate, and act on such 'soft…

机器人学 · 计算机科学 2023-09-01 Luke Burks , Hunter M. Ray , Jamison McGinley , Sousheel Vunnam , Nisar Ahmed

LLMs enable an exciting new class of data processing applications over large collections of unstructured documents. Several new programming frameworks have enabled developers to build these applications by composing them out of semantic…

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