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Understanding how neural population responses represent sensory information is a central problem in systems neuroscience. One approach is to define a representational geometry on stimulus space in which distances reflect how reliably…

神经元与认知 · 定量生物学 2026-05-08 Simone Azeglio , Steeve Laquitaine , Ulisse Ferrari , Matthew Chalk

By recording multiple cells simultaneously, electrophysiologists have found evidence for repeating spatiotemporal spike patterns, which can carry information. How this information is extracted by downstream neurons is unclear. In this…

神经与进化计算 · 计算机科学 2017-07-05 Timothée Masquelier

The combination of new recording techniques in neuroscience and powerful inference methods recently held the promise to recover useful effective models, at the single neuron or network level, directly from observed data. The value of a…

神经元与认知 · 定量生物学 2018-04-09 Cristiano Capone , Guido Gigante , Paolo Del Giudice

The nervous system represents time-dependent signals in sequences of discrete action potentials or spikes, all spikes are identical so that information is carried only in the spike arrival times. We show how to quantify this information, in…

凝聚态物理 · 物理学 2008-02-03 S. P. Strong , Roland Koberle , Rob R. de Ruyter van Steveninck , William Bialek

We present a first-order non-homogeneous Markov model for the interspike-interval density of a continuously stimulated spiking neuron. The model allows the conditional interspike-interval density and the stationary interspike-interval…

神经元与认知 · 定量生物学 2012-08-15 J. Tapson , C. Jin , A. van Schaik , R. Etienne-Cummings

The capacity with which a system of independent neuron-like units represents a given set of stimuli is studied by calculating the mutual information between the stimuli and the neural responses. Both discrete noiseless and continuous noisy…

无序系统与神经网络 · 物理学 2007-05-23 Ines Samengo , Alessandro Treves

Contemporary modeling approaches to the dynamics of neural networks consider two main classes of models: biologically grounded spiking neurons and functionally inspired rate-based units. The unified simulation framework presented here…

神经元与认知 · 定量生物学 2017-11-27 Jan Hahne , David Dahmen , Jannis Schuecker , Andreas Frommer , Matthias Bolten , Moritz Helias , Markus Diesmann

A steadily increasing body of evidence suggests that the brain performs probabilistic inference to interpret and respond to sensory input and that trial-to-trial variability in neural activity plays an important role. The neural sampling…

神经元与认知 · 定量生物学 2017-07-07 Ilja Bytschok , Dominik Dold , Johannes Schemmel , Karlheinz Meier , Mihai A. Petrovici

Entropy and mutual information in neural networks provide rich information on the learning process, but they have proven difficult to compute reliably in high dimensions. Indeed, in noisy and high-dimensional data, traditional estimates in…

计算机视觉与模式识别 · 计算机科学 2023-12-11 Danqi Liao , Chen Liu , Benjamin W. Christensen , Alexander Tong , Guillaume Huguet , Guy Wolf , Maximilian Nickel , Ian Adelstein , Smita Krishnaswamy

One step in the conventional analysis of extracellularly recorded neuronal data is spike sorting, which separates electrical signal into action potentials from different neurons. Because spike sorting involves human judgment, it can be…

神经元与认知 · 定量生物学 2007-05-23 Artur Luczak , Nandakumar S. Narayanan

Stimulus dimensionality-reduction methods in neuroscience seek to identify a low-dimensional space of stimulus features that affect a neuron's probability of spiking. One popular method, known as maximally informative dimensions (MID), uses…

神经元与认知 · 定量生物学 2015-02-26 Ross S. Williamson , Maneesh Sahani , Jonathan W. Pillow

Foundation models have shown remarkable success in fitting biological visual systems; however, their black-box nature inherently limits their utility for understanding brain function. Here, we peek inside a SOTA foundation model of neural…

神经元与认知 · 定量生物学 2026-01-30 Johannes Bertram , Luciano Dyballa , Anderson Keller , Savik Kinger , Steven W. Zucker

Spiking Neural Networks (SNNs) has the ability to extract spatio-temporal features due to their spiking sequence. While previous research has primarily foucus on the classification of image and reinforcement learning. In our paper, we put…

机器人学 · 计算机科学 2025-03-18 Qianhao Wang , Yinqian Sun , Enmeng Lu , Qian Zhang , Yi Zeng

Neural encoding plays an important role in faithfully describing the temporally rich patterns, whose instances include human speech and environmental sounds. For tasks that involve classifying such spatio-temporal patterns with the Spiking…

神经与进化计算 · 计算机科学 2019-09-27 Zihan Pan , Jibin Wu , Yansong Chua , Malu Zhang , Haizhou Li

Identifying stimulus-driven neural activity patterns is critical for studying the neural basis of cognition. This can be particularly challenging in intracranial datasets, where electrode locations typically vary across patients. This…

神经元与认知 · 定量生物学 2022-02-07 Jeremy R. Manning

While spike timing has been shown to carry detailed stimulus information at the sensory periphery, its possible role in network computation is less clear. Most models of computation by neural networks are based on population firing rates.…

神经元与认知 · 定量生物学 2015-07-17 Michael A. Schwemmer , Adrienne L. Fairhall , Sophie Denéve , Eric T. Shea-Brown

A good understanding of how neurons use electrical pulses (i.e, spikes) to encode the signal information remains elusive. Analyzing spike sequences generated by individual neurons and by two coupled neurons (using the stochastic…

神经元与认知 · 定量生物学 2019-10-23 Maria Masoliver , Cristina Masoller

We consider the evolution of a network of neurons, focusing on the asymptotic behavior of spikes dynamics instead of membrane potential dynamics. The spike response is not sought as a deterministic response in this context, but as a…

数据分析、统计与概率 · 物理学 2010-08-27 J. C. Vasquez , B. Cessac , T. Viéville

Complementary Learning Systems theory holds that intelligent agents need two learning systems. Semantic memory is encoded in the neocortex with dense, overlapping representations and acquires structured knowledge. Episodic memory is encoded…

机器学习 · 计算机科学 2025-09-03 Lucie Fontaine , Frédéric Alexandre

Animals rely on different decision strategies when faced with ambiguous or uncertain cues. Depending on the context, decisions may be biased towards events that were most frequently experienced in the past, or be more explorative. A…

神经元与认知 · 定量生物学 2023-05-10 Younes Bouhadjar , Dirk J. Wouters , Markus Diesmann , Tom Tetzlaff