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Cells sense external concentrations and, via biochemical signaling, respond by regulating the expression of target proteins. Both in signaling networks and gene regulation there are two main mechanisms by which the concentration can be…

亚细胞过程 · 定量生物学 2017-04-12 Gabriele Micali , Gerardo Aquino , David M. Richards , Robert G. Endres

Past work has reported inverted-U relationships between arousal and auditory task performance, but the underlying neural network mechanisms remain unclear. To make progress, we recorded auditory cortex activity from behaving mice during…

神经元与认知 · 定量生物学 2025-11-05 Lia Papadopoulos , Suhyun Jo , Kevin Zumwalt , Michael Wehr , Santiago Jaramillo , David A. McCormick , Luca Mazzucato

Gene expression is a biochemical process, where stochastic binding and un-binding events naturally generate fluctuations and cell-to-cell variability in gene dynamics. These fluctuations typically have destructive consequences for proper…

种群与进化 · 定量生物学 2022-03-22 Yen Ting Lin , Nicolas E. Buchler

A simple threshold model of neuron firing (with the neuron membrane electrochemical potential governed by the chaotic Rossler attractor) has been analyzed by mapping the generated irregular spiking time-series into telegraph signals. In…

神经元与认知 · 定量生物学 2011-04-19 A. Bershadskii , Y. Ikegaya

Coherent oscillatory activity can arise spontaneously as a result of increased coupling in a system of excitable and passive cells, each being quiescent in isolation. This can potentially explain the appearance of spontaneous rhythmic…

无序系统与神经网络 · 物理学 2012-12-17 Jinshan Xu , Rajeev Singh , Nicolas Garnier , Sitabhra Sinha , Alain Pumir

The dynamics of many nanoscale biological and synthetic systems such as enzymes and molecular motors are activated by thermal noise, and driven out-of-equilibrium by local energy dissipation. Because the energies dissipated in these systems…

统计力学 · 物理学 2025-05-27 Michalis Chatzittofi , Ramin Golestanian , Jaime Agudo-Canalejo

Inspired by Axelrod's model of culture dissemination, we introduce and analyze a model for a population of coupled oscillators where different levels of synchronization can be assimilated to different degrees of cultural organization. The…

适应与自组织系统 · 物理学 2015-05-13 M. N. Kuperman , D. H. Zanette

Coupling among neural rhythms is one of the most important mechanisms at the basis of cognitive processes in the brain. In this study we consider a neural mass model, rigorously obtained from the microscopic dynamics of an inhibitory…

适应与自组织系统 · 物理学 2020-06-24 Andrea Ceni , Simona Olmi , Alessandro Torcini , David Angulo-Garcia

We analyze the noise induced synchronization between a collective variable characterizing a complex system with a finite number of interacting bistable units and time periodic driving forces. A random phase process associated to the…

统计力学 · 物理学 2009-11-13 José M. Casado , José Gómez-Ordóñez , Manuel Morillo

We introduce an open-source solver for the Lindblad master equation, based on matrix product states and matrix product operators. Using this solver we study the dynamics of tens of interacting qubits with different connectivities, focusing…

量子物理 · 物理学 2022-11-15 H. Landa , G. Misguich

The study of synchronization in biological systems is essential for the understanding of the rhythmic phenomena of living organisms at both molecular and cellular levels. In this paper, by using simple dynamical systems theory, we present a…

分子网络 · 定量生物学 2007-05-23 Chunguang Li , Luonan Chen , Kazuyuki Aihara

We study synchronization of locally coupled noisy phase oscillators which move diffusively in a one-dimensional ring. Together with the disordered and the globally synchronized states, the system also exhibits several wave-like states which…

生物物理 · 物理学 2010-09-22 Fernando Peruani , Ernesto M. Nicola , Luis G. Morelli

A widely accepted view of computations in the brain relies on population coding, where the neural ensemble firing rate is modulated in a stable manner to transmit information and perform various cognitive tasks. At the same time,…

神经元与认知 · 定量生物学 2020-05-27 Nikita Novikov , Boris Gutkin

Synchronized neural spiking is associated with many cognitive functions and thus, merits study for its own sake. The analysis of neural synchronization naturally leads to the study of repetitive spiking and consequently to the analysis of…

神经元与认知 · 定量生物学 2017-07-19 Youngmin Park , Stewart Heitmann , G. Bard Ermentrout

We consider the general open system problem of a charged quantum oscillator confined in a harmonic trap, whose frequency can be arbitrarily modulated in time, that interacts with both an incoherent quantized (blackbody) radiation field and…

量子物理 · 物理学 2014-01-14 Leonardo A. Pachón , Paul Brumer

The suprachiasmatic nucleus (SCN), also known as the circadian master clock, consists of a large population of oscillator neurons. Together, these neurons produce a coherent signal that drives the body's circadian rhythms. What properties…

神经元与认知 · 定量生物学 2023-01-04 Stéphanie M. C. Abo , José A. Carrillo , Anita T. Layton

Synchronization is ubiquitous in nature at various scales and fields. This phenomenon not only offers a window into the intrinsic harmony of complex systems, but also serves as a robust probe for many-body quantum systems. One such system…

Considering an array of spin torque transfer nano oscillators (STNOs), we have investigated the synchronization property of the system under the action of a common periodically driven applied external magnetic field by numerically analyzing…

混沌动力学 · 物理学 2014-06-17 B. Subash , V. K. Chandrasekar , M. Lakshmanan

This book chapter describes the dynamics of a modulated oscillator for resonant and nonresonant modulation. Two types of resonant modulation are considered: additive, with frequency close to the oscillator eigenfrequency, and parametric,…

介观与纳米尺度物理 · 物理学 2011-12-13 M. I. Dykman

Many biological systems can sense periodical variations in a stimulus input and produce well-timed, anticipatory responses after the input is removed. Such systems show memory effects for retaining timing information in the stimulus and…

神经元与认知 · 定量生物学 2015-09-09 Ying-Jen Yang , Chun-Chung Chen , Pik-Yin Lai , C. K. Chan