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In the brain, both neurons and glial cells work in conjunction with each other during information processing. Stimulation of neurons can cause calcium oscillations in astrocytes which in turn can affect neuronal calcium dynamics. The…

神经元与认知 · 定量生物学 2023-08-16 Bhanu Sharma , Spandan Kumar , Subhendu Ghosh , Vikram Singh

We report a spectrum of exotic frequency-locked states in a ring of phase oscillators with pure three-body interactions. For identical oscillators, the system hosts a vast multiplicity of stable quantized frequency-locked states without…

斑图形成与孤子 · 物理学 2025-12-23 Jinfeng Liang , Shanshan Zhu , Yang Li , Qionglin Dai , Haihong Li , Junzhong Yang

A recurring motif in gene regulatory networks is transcription factors (TFs) that regulate each other, and then bind to overlapping sites on DNA, where they interact and synergistically control transcription of a target gene. Here, we…

分子网络 · 定量生物学 2013-03-07 Sahand Hormoz

We study phase synchronization for a ratchet system. We consider the deterministic dynamics of a particle in a tilted ratchet potential with an external periodic forcing, in the overdamped case. The ratchet potential has to be tilted in…

其他凝聚态物理 · 物理学 2009-11-11 Fernando R. Alatriste , José L. Mateos

The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…

生物物理 · 物理学 2019-09-04 Matteo Campo , Simon K. Schnyder , John J. Molina , Thomas Speck , Ryoichi Yamamoto

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…

细胞行为 · 定量生物学 2019-07-08 Shou-Wen Wang , Lei-Han Tang

Electroencephalographic neurofeedback (EEG-NF) has been proposed as a promising technique to modulate brain activity through real-time EEG-based feedback. Alpha neurofeedback in particular is believed to induce rapid self-regulation of…

神经元与认知 · 定量生物学 2025-09-15 Jacob Maaz , Laurent Waroquier , Alexandra Dia , Véronique Paban , Arnaud Rey

We study a problem of designing ``robust'' external excitations for control and synchronization of an assembly of homotypic harmonic oscillators representing so-called theta neurons. The model of theta neurons (Theta model) captures, in…

Flexible modulation of temporal dynamics in neural sequences underlies many cognitive processes. For instance, we can adaptively change the speed of motor sequences and speech. While such flexibility is influenced by various factors such as…

神经元与认知 · 定量生物学 2025-04-15 Tomoki Kurikawa , Kunihiko Kaneko

Coordinated responses to environmental stimuli are critical for multicellular organisms. To overcome the obstacles of cell-to-cell heterogeneity and noisy signaling dynamics within individual cells, cells must effectively exchange…

生物物理 · 物理学 2022-10-12 Guanyu Li , Ryan LeFebre , Alia Starman , Patrick Chappell , Andrew Mugler , Bo Sun

A new stimulation paradigm is presented for the stimulation of nerve cells by extracellular electric currents. In the new paradigm stimulation is achieved with the current spike induced by a voltage step whenever the voltage step is applied…

其他定量生物学 · 定量生物学 2016-03-08 Erich W. Schmid

Multiple organs in a living system respond to environmental changes, and the signals from the organs regulate the physiological environment. Inspired by this biological feedback, we propose a simple autonomous system of active rotators to…

统计力学 · 物理学 2020-03-02 Taegeun Song , Heetae Kim , Seung-Woo Son , Junghyo Jo

In the paper we investigate a mathematical model describing the growth of tumor in the presence of immune response of a host organism. The dynamics of tumor and immune cells is based on the generic Michaelis-Menten kinetics depicting…

Ultrafast perturbations offer a unique tool to manipulate correlated systems due to their ability to promote transient behaviors with no equilibrium counterpart. A widely employed strategy is the excitation of coherent optical phonons, as…

超导电性 · 物理学 2018-01-24 Michael Schütt , Peter P. Orth , Alex Levchenko , Rafael M. Fernandes

Gene expression is a noisy process that leads to regime shift between alternative steady states among individual living cells, inducing phenotypic variability. The effects of white noise on the regime shift in bistable systems have been…

分子网络 · 定量生物学 2017-08-23 Yogita Sharma , Partha Sharathi Dutta

Many natural and industrial turbulent flows are subjected to time-dependent boundary conditions. Despite being ubiquitous, the influence of temporal modulations (with frequency $f$) on global transport properties has hardly been studied.…

流体动力学 · 物理学 2020-10-14 Rui Yang , Kai Leong Chong , Qi Wang , Roberto Verzicco , Olga Shishkina , Detlef Lohse

The phenomenon of synchronization, where entities exhibit stable oscillations with aligned frequencies and phases, has been detected in diverse areas of natural science. It plays a crucial role in achieving frequency locking in multiple…

量子物理 · 物理学 2025-06-24 Tong Liu , Laura García-Álvarez , Giovanna Tancredi

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

神经元与认知 · 定量生物学 2014-05-01 Daniel Soudry , Ron Meir

Brain dynamics can exhibit narrow-band nonlinear oscillations and multistability. For a subset of disorders of consciousness and motor control, we hypothesize that some symptoms originate from the inability to spontaneously transition from…

神经元与认知 · 定量生物学 2020-06-24 Ian D. Jordan , Il Memming Park