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A fundamental problem in neuroscience is to characterize the dynamics of spiking from the neurons in a circuit that is involved in learning about a stimulus or a contingency. A key limitation of current methods to analyze neural spiking…

统计方法学 · 统计学 2017-09-29 Yingzhuo Zhang , Noa Malem-Shinitski , Stephen A Allsop , Kay Tye , Demba Ba

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

神经元与认知 · 定量生物学 2014-05-01 Daniel Soudry , Ron Meir

Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

神经元与认知 · 定量生物学 2012-03-06 Xuejuan Zhang , Jianfeng Feng

For deep neural networks (DNNs) to be used in safety-critical autonomous driving tasks, it is desirable to monitor in operation time if the input for the DNN is similar to the data used in DNN training. While recent results in monitoring…

机器学习 · 计算机科学 2021-09-28 Chih-Hong Cheng

Stochastic oscillators based on emerging nanodevices are attractive because of their ultra-low power requirement and ability to exhibit stochastic resonance, a phenomenon where synchronization to weak input signals is enabled due to ambient…

介观与纳米尺度物理 · 物理学 2024-06-19 Punyashloka Debashis , Aman K. Maskay , Pramey Upadhyaya , Zhihong Chen

Vanilla spiking neurons in Spiking Neural Networks (SNNs) use charge-fire-reset neuronal dynamics, which can only be simulated serially and can hardly learn long-time dependencies. We find that when removing reset, the neuronal dynamics can…

神经与进化计算 · 计算机科学 2024-01-10 Wei Fang , Zhaofei Yu , Zhaokun Zhou , Ding Chen , Yanqi Chen , Zhengyu Ma , Timothée Masquelier , Yonghong Tian

Spiking neural networks (SNNs) promise low-power event-driven computation for temporally rich tasks, but commonly used neuron models often trade off gradient-based trainability, dynamical richness, and high activity sparsity. These…

神经与进化计算 · 计算机科学 2026-05-13 Alex Fulleda-Garcia , Saray Soldado-Magraner , Josep Maria Margarit-Taulé

Cortical activity in-vivo displays relaxational time scales much longer than the membrane time constant of the neurons or the deactivation time of ionotropic synaptic conductances. The mechanisms responsible for such slow dynamics are not…

无序系统与神经网络 · 物理学 2025-08-07 Ferdinand Tixidre , Gianluigi Mongillo , Alessandro Torcini

The relationship between complex, brain oscillations and the dynamics of individual neurons is poorly understood. Here we utilize Maximum Caliber, a dynamical inference principle, to build a minimal, yet general model of the collective…

神经元与认知 · 定量生物学 2020-09-04 Corey Weistuch , Lilianne R. Mujica-Parodi , Ken Dill

A wide variety of engineered and natural systems are modelled as networks of coupled nonlinear oscillators. In nature, the intrinsic frequencies of these oscillators are not constant in time. Here, we probe the effect of such a temporal…

Frequency modulation experiments were performed on a spin torque vortex oscillator for a wide range of modulation frequency, up to 10 % of the oscillator frequency. A thorough analysis of the intermodulation products shows that the key…

介观与纳米尺度物理 · 物理学 2013-06-25 S. Y. Martin , C. Thirion , C. Hoarau , C. Baraduc , B. Diény

First spike latency following stimulus onset is of significant physiological relevance. Neurons transmit information about their inputs by transforming them into spike trains, and the timing of these spike trains is in turn crucial for…

生物物理 · 物理学 2014-03-27 Rukiye Uzun , Mahmut Ozer , Matjaz Perc

We study the internal resonance, energy transfer, activation mechanism, and control of a model of DNA division via parametric resonance. While the system is robust to noise, this study shows that it is sensitive to specific fine scale modes…

动力系统 · 数学 2012-11-20 Wang Sang Koon , Houman Owhadi , Molei Tao , Tomohiro Yanao

Almost all organisms show some kind of time periodicity in their behavior. Especially in mammals the neurons of the suprachiasmatic nucleus form a biological clock regulating the activity-inactivity cycle of the animal. This clock is…

适应与自组织系统 · 物理学 2011-11-24 Domien G. M. Beersma , Henk W. Broer , Konstantinos Efstathiou , Kim A. Gargar , Igor Hoveijn

Neural systems process information across a broad range of intrinsic timescales, both within and across cortical areas. While such diversity is a hallmark of biological networks, its computational role in nonlinear information processing…

神经元与认知 · 定量生物学 2025-06-10 Tomoki Kurikawa

We present a design framework to induce stable oscillations through mixed feedback control. We provide conditions on the feedback gain and on the balance between positive and negative feedback contributions to guarantee robust oscillations.…

系统与控制 · 电气工程与系统科学 2023-05-09 Weiming Che , Fulvio Forni

Recurrent neural networks (RNNs) are machine learning models widely used for learning temporal relationships. Current state-of-the-art RNNs use integrating or spiking neurons -- two classes of computing units whose outputs depend directly…

神经与进化计算 · 计算机科学 2025-06-10 Peter DelMastro , Arjun Karuvally , Hananel Hazan , Hava Siegelmann , Edward Rietman

This technical note introduces parametric dynamic causal modelling, a method for inferring slow changes in biophysical parameters that control fluctuations of fast neuronal states. The application domain we have in mind is inferring slow…

定量方法 · 定量生物学 2020-08-27 Amirhossein Jafarian , Peter Zeidman , Rob. C Wykes , Matthew Walker , Karl J. Friston

Synchronization of oscillations is a phenomenon prevalent in natural, social, and engineering systems. Controlling synchronization of oscillating systems is motivated by a wide range of applications from neurological treatment of…

最优化与控制 · 数学 2015-03-19 Jr-Shin Li , Isuru Dasanayake , Justin Ruths

Noise can shape the firing behaviors of neurons. Here, we show that noise acting on the fast variable of the Hedgehog burster can tune the spike counts of bursts via the self-induced stochastic resonance (SISR) phenomenon. Using the…

适应与自组织系统 · 物理学 2022-07-29 Jinjie Zhu , Hiroya Nakao