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Monitoring the dose delivered during proton and carbon ion therapy is still a matter of research. Among the possible solutions, several exploit the measurement of the single photon emission from nuclear decays induced by the irradiation. To…
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments and the on-line knowledge of the Bragg peak position is still a matter of research.…
Hadrontherapy is an emerging technique in cancer therapy that uses beams of charged particles. To meet the improved capability of hadrontherapy in matching the dose release with the cancer position, new dose monitoring techniques need to be…
Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…
Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…
Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…
Ion beam therapy has become a frequently applied form of cancer therapy over the last years. The advantage of ion beam therapy over conventional radiotherapy using photons is the strongly localized dose deposition, leading to a reduction of…
Hadron therapy, because of the dosimetric and radiobiological advantages, is more and more often used in tumour treatment. This treatment method leads also to the radioactive effects induced by energetic protons on nuclei. Nuclear reactions…
Cancer therapy using protons and heavier ions such as carbon has demonstrated advantages over other radiotherapy treatments. To bring about the next generation of clinical facilities, the requirements are likely to reduce the footprint,…
The energy spectrum for high energy $\gamma$-rays ($E_\gamma \geq 10$ MeV) from the process $pp \to \gamma \gamma X$ emitted at $90^0$ in the laboratory frame has been measured at an energy below the pion production threshold, namely, at…
Nowadays there is a growing interest in Particle Therapy treatments exploiting light ion beams against tumors due to their enhanced Relative Biological Effectiveness and high space selectivity. In particular promising results are obtained…
Fast procedures for the beam quality assessment and for the monitoring of beam energy modulations during the irradiation are among the most urgent improvements in particle therapy. Indeed, the online measurement of the particle beam energy…
In carbon-therapy, the interaction of the incoming beam with human tissues may lead to the production of a large amount of nuclear fragments and secondary light particles. An accurate estimation of the biological dose deposited into the…
Proton (and ion) cancer therapy has proven to be an extremely effective even supe-rior method of treatment for some tumors 1-4. A major problem, however, lies in the cost of the particle accelerator facilities; high procurement costs…
The energy spectrum for high energy $\gamma$-rays ($E_\gamma \geq 10$ MeV) from the process $pp \to \gamma \gamma X$ emitted at $90^0$ in the laboratory frame has been measured at 216 MeV. The resulting photon energy spectrum extracted from…
Carbon ion therapy is one of the most advanced forms of radiotherapy, promising improved efficacy against resistant cancers. However, the high precision offered by the carbon ion Bragg peak requires precise knowledge of the beam range…
Monte Carlo simulations have been performed in order to evaluate the efficiencies of several light ions identification techniques. The detection system was composed with layers of scintillating material to measure either the deposited…
The purpose of this study was to investigate the feasibility of extracting proton beams with two distinct energies within a single synchrotron cycle. The energy difference between the beams should be sufficient to use one beam as a range…
In the context of range monitoring for particle therapy, this study presents the first experimental results obtained with the TIARA detector using carbon-ion beams at the CNAO clinical center in Pavia, Italy. TIARA is based on the Prompt…
Prompt Gamma Timing (PGT) is a promising technique for in vivo range verification in particle therapy, exploiting the time-of-flight between primary particles and prompt gamma rays emitted by nuclear interactions. PGT distribution is highly…