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While surrogate backpropagation proves useful for training deep spiking neural networks (SNNs), incorporating biologically inspired local signals on a large scale remains challenging. This difficulty stems primarily from the high memory…

神经与进化计算 · 计算机科学 2025-12-09 Yuchen Tian , Samuel Tensingh , Jason Eshraghian , Nhan Duy Truong , Omid Kavehei

We analyze continuous Hopfield associative memories augmented by additional, rapid short-term associative synaptic plasticity. Through the cavity method, we determine the boundary between the retrieval and forgetting, or spin-glass phase,…

神经元与认知 · 定量生物学 2026-02-10 Martina Del Gaudio , Federico Ghimenti , Surya Ganguli

The degrees of freedom of multi-compartment mathematical models for energy metabolism of a neuron-astrocyte complex may offer a key to understand the different ways in which the energetic needs of the brain are met. In this paper we address…

定量方法 · 定量生物学 2014-12-19 Daniela Calvetti , Yougan Cheng , Erkki Somersalo

Neural circuits exhibit remarkable computational flexibility, enabling adaptive responses to noisy and ever-changing environmental cues. A fundamental question in neuroscience concerns how a wide range of behaviors can emerge from a…

统计力学 · 物理学 2025-09-18 Giacomo Barzon , Daniel M. Busiello , Giorgio Nicoletti

The potential of memristive devices is often seeing in implementing neuromorphic architectures for achieving brain-like computation. However, the designing procedures do not allow for extended manipulation of the material, unlike CMOS…

新兴技术 · 计算机科学 2016-04-25 Shari Lim Wei , Eleni Vasilaki , Ali Khiat , Iulia Salaoru , Radu Berdan , Themistoklis Prodromakis

A pre-synaptic neuron releases diffusing neurotransmitters such as glutamate that activate post-synaptic receptors. The amplitude of the post-synaptic current, mostly mediated by glutamatergic (AMPARs) receptors, is a fundamental signal…

神经元与认知 · 定量生物学 2015-05-19 Adi Taflia , David Holcman

The participation of astrocytes in brain computation was formally hypothesized in 1992, coinciding with the discovery that these glial cells display a complex form of Ca2+ excitability. This fostered conceptual advances centered on the…

神经元与认知 · 定量生物学 2023-10-23 Ciaran Murphy-Royal , ShiNung Ching , Thomas Papouin

Latency reduction of postsynaptic spikes is a well-known effect of Synaptic Time-Dependent Plasticity. We expand this notion for long postsynaptic spike trains, showing that, for a fixed input spike train, STDP reduces the number of…

神经元与认知 · 定量生物学 2019-07-26 Pau Vilimelis Aceituno , Masud Ehsani , Jürgen Jost

We introduce a Hopfield-type associative memory in which effective connectivity is multiplicatively modulated by astrocytic gains evolving under an entropy-regularized replicator equation. The coupled neuron-astrocyte dynamics admit a…

数据分析、统计与概率 · 物理学 2026-04-29 Arnau Vivet , Alex Arenas

As a means of dynamically reconfiguring the synaptic weight of a superconducting optoelectronic loop neuron, a superconducting flux storage loop is inductively coupled to the synaptic current bias of the neuron. A standard flux memory cell…

General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features…

神经与进化计算 · 计算机科学 2016-02-17 David Kappel , Stefan Habenschuss , Robert Legenstein , Wolfgang Maass

Spike-timing-dependent plasticity(STDP) is a biological process of synaptic modification caused by the difference of firing order and timing between neurons. One of the neurodynamical roles of STDP is to form a macroscopic geometrical…

神经元与认知 · 定量生物学 2021-08-10 Hong-Gyu Yoon , Pilwon Kim

Neuromorphic Computing (NC), which emulates neural activities of the human brain, is considered for low-power implementation of artificial intelligence. Towards realizing NC, fabrication, and investigations of hardware elements such as…

材料科学 · 物理学 2021-09-21 P. Monalisha , P. S. Anil Kumar , X. Renshaw Wang , S. N. Piramanayagam

The energetics of cerebral activity critically relies on the functional and metabolic interactions between neurons and astrocytes. Important open questions include the relation between neuronal versus astrocytic energy demand, glucose…

While neuromorphic computing architectures based on Spiking Neural Networks (SNNs) are increasingly gaining interest as a pathway toward bio-plausible machine learning, attention is still focused on computational units like the neuron and…

神经与进化计算 · 计算机科学 2023-03-10 Zhuangyu Han , A N M Nafiul Islam , Abhronil Sengupta

Large networks of spiking neurons show abrupt changes in their collective dynamics resembling phase transitions studied in statistical physics. An example of this phenomenon is the transition from irregular, noise-driven dynamics to…

适应与自组织系统 · 物理学 2008-11-25 Vicenç Gómez , Andreas Kaltenbrunner , Vicente López , Hilbert J. Kappen

Synaptic delays play a crucial role in biological neuronal networks, where their modulation has been observed in mammalian learning processes. In the realm of neuromorphic computing, although spiking neural networks (SNNs) aim to emulate…

神经与进化计算 · 计算机科学 2025-06-19 Marissa Dominijanni , Alexander Ororbia , Kenneth W. Regan

Humans and animals learn throughout life. Such continual learning is crucial for intelligence. In this chapter, we examine the pivotal role plasticity mechanisms with complex internal synaptic dynamics could play in enabling this ability in…

神经元与认知 · 定量生物学 2024-10-21 Friedemann Zenke , Axel Laborieux

Dendritic spines are small membranous structures that protrude from the neuronal dendrite. Each spine contains a synaptic contact site that may connect its parent dendrite to the axons of neighboring neurons. Dendritic spines are markedly…

生物物理 · 物理学 2015-11-02 Karsten Miermans , Remy Kusters , Casper Hoogenraad , Cornelis Storm

Triplet-based Spike Timing Dependent Plasticity (TSTDP) is a powerful synaptic plasticity rule that acts beyond conventional pair-based STDP (PSTDP). Here, the TSTDP is capable of reproducing the outcomes from a variety of biological…

神经与进化计算 · 计算机科学 2013-04-02 Mostafa Rahimi Azghadi , Said Al-Sarawi , Derek Abbott , Nicolangelo Iannella