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AI-enabled precision medicine promises a transformational improvement in healthcare outcomes by enabling data-driven personalized diagnosis, prognosis, and treatment. However, the well-known "curse of dimensionality" and the clustered…

机器学习 · 计算机科学 2023-05-19 Amanda M. Buch , Conor Liston , Logan Grosenick

Forecasting is critical in areas such as finance, biology, and healthcare. Despite the progress in the field, making accurate forecasts remains challenging because real-world time series contain both global trends, local fine-grained…

机器学习 · 计算机科学 2026-01-01 Zihao Chen , Alexandre Andre , Wenrui Ma , Ian Knight , Sergey Shuvaev , Eva Dyer

As the size and richness of available datasets grow larger, the opportunities for solving increasingly challenging problems with algorithms learning directly from data grow at the same pace. Consequently, the capability of learning…

机器学习 · 计算机科学 2019-12-13 Raffaello Camoriano

Understanding the dynamic behavior of proteins is critical to elucidating their functional mechanisms, yet generating realistic, temporally coherent trajectories of protein ensembles remains a significant challenge. In this work, we…

生物大分子 · 定量生物学 2025-11-11 Yaoyao Xu , Di Wang , Zihan Zhou , Tianshu Yu , Mingchen Chen

This paper proposes a hierarchical approximate-factor approach to analyzing high-dimensional, large-scale heterogeneous time series data using distributed computing. The new method employs a multiple-fold dimension reduction procedure using…

统计方法学 · 统计学 2022-04-20 Zhaoxing Gao , Ruey S. Tsay

In this paper, we propose a new time-aware dissimilarity measure that takes into account the temporal dimension. Observations that are close in the description space, but distant in time are considered as dissimilar. We also propose a…

机器学习 · 计算机科学 2016-01-13 Marian-Andrei Rizoiu , Julien Velcin , Stéphane Lallich

Time series generation is critical for a wide range of applications, which greatly supports downstream analytical and decision-making tasks. However, the inherent temporal heterogeneous induced by localized perturbations present significant…

机器学习 · 计算机科学 2025-11-19 Jintao Zhang , Mingyue Cheng , Zirui Liu , Xianquan Wang , Yitong Zhou , Qi Liu

Predictive clustering trees (PCTs) are a well established generalization of standard decision trees, which can be used to solve a variety of predictive modeling tasks, including structured output prediction. Combining them into ensembles…

机器学习 · 计算机科学 2020-11-06 Tomaž Stepišnik , Dragi Kocev

Frequent temporal patterns discovered in time-interval-based multivariate data, although syntactically correct, might be non-transparent: For some pattern instances, there might exist intervals for the same entity that contradict the…

机器学习 · 计算机科学 2021-01-12 Alexander Shknevsky , Yuval Shahar , Robert Moskovitch

The matrix profile is an effective data mining tool that provides similarity join functionality for time series data. Users of the matrix profile can either join a time series with itself using intra-similarity join (i.e., self-join) or…

Model-based clustering is a powerful tool that is often used to discover hidden structure in data by grouping observational units that exhibit similar response values. Recently, clustering methods have been developed that permit…

统计方法学 · 统计学 2025-06-24 Sally Paganin , Garritt L. Page , Fernando Andrés Quintana

Spatial domain identification requires jointly modeling molecular signatures and physical coordinates, yet current tools frequently over-smooth biological boundaries, require user-specified cluster numbers, and lack principled multimodal…

应用统计 · 统计学 2026-05-18 Xin Li , Xiaofei Dong , Zhenke Duan , Lulu Shang , Xiao Wang , Xinyuan Song , Hanwen Ning , Guanyu Hu

We propose a method for linear-time diversity maintenance in particle filtering. It clusters particles based on ancestry tree topology: closely related particles in sufficiently large subtrees are grouped together. The main idea is that the…

机器人学 · 计算机科学 2025-09-30 Ilari Vallivaara , Bingnan Duan , Yinhuan Dong , Tughrul Arslan

Subspace clustering refers to the problem of clustering high-dimensional data into a union of low-dimensional subspaces. Current subspace clustering approaches are usually based on a two-stage framework. In the first stage, an affinity…

机器学习 · 计算机科学 2019-10-22 Shuai Yang , Wenqi Zhu , Yuesheng Zhu

Clustering multidimensional points is a fundamental data mining task, with applications in many fields, such as astronomy, neuroscience, bioinformatics, and computer vision. The goal of clustering algorithms is to group similar objects…

分布式、并行与集群计算 · 计算机科学 2023-05-22 Yihao Huang , Shangdi Yu , Julian Shun

Temporal role-based access control (TRBAC) extends role-based access control to limit the times at which roles are enabled. This paper presents a new algorithm for mining high-quality TRBAC policies from timed ACLs (i.e., ACLs with time…

密码学与安全 · 计算机科学 2017-10-17 Scott D. Stoller , Thang Bui

In this study, we present a method of pattern mining based on network theory that enables the identification of protein structures or complexes from synthetic volume densities, without the knowledge of predefined templates or human biases…

定量方法 · 定量生物学 2022-10-18 August George , Doo Nam Kim , Trevor Moser , Ian T. Gildea , James E. Evans , Margaret S. Cheung

Longitudinal studies are vital to understanding dynamic changes of the planet, but labels (e.g., buildings, facilities, roads) are often available only for a single point in time. We propose a general model, Temporal Cluster Matching (TCM),…

计算机视觉与模式识别 · 计算机科学 2021-06-30 Caleb Robinson , Anthony Ortiz , Juan M. Lavista Ferres , Brandon Anderson , Daniel E. Ho

Subsequence clustering of time series is an essential task in data mining, and interpreting the resulting clusters is also crucial since we generally do not have prior knowledge of the data. Thus, given a large collection of tensor time…

机器学习 · 计算机科学 2024-02-23 Kohei Obata , Koki Kawabata , Yasuko Matsubara , Yasushi Sakurai

Post-translational modifications (PTMs) profoundly expand the complexity and functionality of the proteome, regulating protein attributes and interactions that are crucial for biological processes. Accurately predicting PTM sites and their…

机器学习 · 计算机科学 2024-11-05 Cheng Tan , Zhenxiao Cao , Zhangyang Gao , Lirong Wu , Siyuan Li , Yufei Huang , Jun Xia , Bozhen Hu , Stan Z. Li
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