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Motivated by modern observational studies, we introduce a class of functional models that expands nested and crossed designs. These models account for the natural inheritance of correlation structure from sampling design in studies where…

应用统计 · 统计学 2013-04-26 Haochang Shou , Vadim Zipunnikov , Ciprian M. Crainiceanu , Sonja Greven

This paper describes how realistic neuromorphic networks can have their connectivity properties fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the…

无序系统与神经网络 · 物理学 2009-11-10 Luciano da F. Costa

The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…

The human brain forms functional networks on all spatial scales. Modern fMRI scanners allow to resolve functional brain data in high resolutions, allowing to study large-scale networks that relate to cognitive processes. The analysis of…

神经元与认知 · 定量生物学 2019-05-14 Melanie Weber , Johannes Stelzer , Emil Saucan , Alexander Naitsat , Gabriele Lohmann , Jürgen Jost

The study of dynamic functional connectomes has provided valuable insights into how patterns of brain activity change over time. Neural networks process information through artificial neurons, conceptually inspired by patterns of activation…

神经元与认知 · 定量生物学 2025-08-12 Yutong Wu , Peilin He , Tananun Songdechakraiwut

Knowing brain connectivity is of great importance both in basic research and for clinical applications. We are proposing a method to infer directed connectivity from zero-lag covariances of neuronal activity recorded at multiple sites. This…

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

机器学习 · 计算机科学 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

Recent studies proposed the use of Total Correlation to describe functional connectivity among brain regions as a multivariate alternative to conventional pair-wise measures such as correlation or mutual information. In this work we build…

神经元与认知 · 定量生物学 2022-11-28 Qiang Li , Greg Ver Steeg , Shujian Yu , Jesus Malo

The central nervous system is composed of many individual units -- from cells to areas -- that are connected with one another in a complex pattern of functional interactions that supports perception, action, and cognition. One natural and…

神经元与认知 · 定量生物学 2017-04-03 Ann E. Sizemore , Danielle S. Bassett

The most studies on functional connectivity have been done by analyzing the brain's hemodynamic response to a stimulation. On the other hand, the low-frequency spontaneous fluctuations in the blood oxygen level dependent (BOLD) signals of…

神经元与认知 · 定量生物学 2012-02-22 Wonsang You , Joerg Stadler

Encoding models provide a powerful framework for linking continuous stimulus features to neural activity; however, traditional voxelwise approaches are limited by measurement noise, inter-subject variability, and redundancy arising from…

计算与语言 · 计算机科学 2026-04-29 Kamya Hari , Taha Binhuraib , Jin Li , Cory Shain , Anna A. Ivanova

Power spectra of awake resting state EEG recordings in humans typically have an Alpha peak at around 10 Hz riding a decreasing background "Xi process". Normal and pathological variations may have more than one peak or none. The single…

神经元与认知 · 定量生物学 2023-01-02 Roberto D. Pascual-Marqui , Kieko Kochi , Toshihiko Kinoshita

Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understanding, or even predicting, this neuromodulatory effect is…

神经元与认知 · 定量生物学 2021-06-29 Christoforos Papasavvas , Peter Neal Taylor , Yujiang Wang

This paper studies the link between resting-state functional connectivity (FC), measured by the correlations of the fMRI BOLD time courses, and structural connectivity (SC), estimated through fiber tractography. Instead of a static analysis…

The extraction of brain functioning features is a crucial step in the definition of brain-computer interfaces (BCIs). In the last decade, functional connectivity (FC) estimators have been increasingly explored based on their ability to…

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

统计理论 · 数学 2008-08-08 Chunming Zhang , Tao Yu

Cortical neurons are subject to sustained and irregular synaptic activity which causes important fluctuations of the membrane potential (Vm). We review here different methods to characterize this activity and its impact on spike generation.…

This paper proposes a novel approach of integrating different neuroimaging techniques to characterize an autistic brain. Different techniques like EEG, fMRI and DTI have traditionally been used to find biomarkers for autism, but there have…

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

神经元与认知 · 定量生物学 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

There is increasing evidence to suggest functional connectivity networks are non-stationary. This has lead to the development of novel methodologies with which to accurately estimate time-varying functional connectivity networks. Many of…