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Human breath contains a myriad of endogenous volatile organic compounds (VOCs) which are reflective of ongoing metabolic or physiological processes. While research into the diagnostic potential and general medical relevance of these trace…

In this paper we develop a simple two compartment model which extends the Farhi equation to the case when the inhaled concentration of a volatile organic compound (VOC) is not zero. The model connects the exhaled breath concentration of…

A real-time recording setup combining exhaled breath VOC measurements by proton transfer reaction mass spectrometry (PTR-MS) with hemodynamic and respiratory data is presented. Continuous automatic sampling of exhaled breath is implemented…

定量方法 · 定量生物学 2009-07-20 J. King , A. Kupferthaler , K. Unterkofler , H. Koc , S. Teschl , G. Teschl , W. Miekisch , J. Schubert , H. Hinterhuber , A. Amann

Isothermal rebreathing has been proposed as an experimental technique for estimating the alveolar levels of hydrophilic volatile organic compounds (VOCs) in exhaled breath. Using the prototypic test compound acetone we demonstrate that the…

Recommended standardized procedures for determining exhaled lower respiratory nitric oxide and nasal nitric oxide have been developed by task forces of the European Respiratory Society and the American Thoracic Society. These…

定量方法 · 定量生物学 2015-03-13 Julian King , Karl Unterkofler , Gerald Teschl , Susanne Teschl , Helin Koc , Hartmann Hinterhuber , Anton Amann

Diabetes is a global health burden, and early detection is critical for timely intervention. This study explores a non-invasive, data-driven framework to identify individuals at risk of diabetes using Volatile Organic Compounds (VOCs) and…

机器学习 · 计算机科学 2026-05-22 Varsha Sharma , Prasanta K. Guha , Avik Ghose

In a recent paper we presented a simple two compartment model which describes the influence of inhaled concentrations on exhaled breath concentrations for volatile organic compounds (VOCs) with small Henry constants. In this paper we extend…

Exhaled breath can be used in retrieving information and creating innovative communication systems. It contains several volatile organic compounds (VOCs) and biological entities that can act as health biomarkers. For instance, the breath of…

信号处理 · 电气工程与系统科学 2018-11-06 Maryam Khalid , Osama Amin , Sajid Ahmed , Basem Shihada , Mohamed-Slim Alouini

Breath acetone represents a promising non-invasive biomarker for monitoring fat oxidation during exercise. However, its utility is limited by confounding factors, as well as by the fact that significant changes in concentration occur only…

Volatile organic compounds (VOCs) in human breath can reveal a large spectrum of health conditions and can be used for fast, accurate and non-invasive diagnostics. Gas chromatography-mass spectrometry (GC-MS) is used to measure VOCs, but…

Breathing rate (BR), minute ventilation (VE), and other respiratory parameters are essential for real-time patient monitoring in many acute health conditions, such as asthma. The clinical standard for measuring respiration, namely…

信号处理 · 电气工程与系统科学 2020-11-26 Ridwan Alam , David B. Peden , John C. Lach

Volatile organic compounds (VOCs) represent a novel but underexplored modality for emotion recognition. This paper presents a systematic evidence synthesis and exploratory investigation of VOC-based affective computing using low-cost…

人机交互 · 计算机科学 2025-12-25 Nicolai Plintz , Marcus Vetter , Dirk Ifenthaler

Exhaled breath condensate (EBC) contains volatile metabolites and is promising for non-invasive disease diagnosis, but after decades of research spanning over 100 biomarkers and 10 diseases, no EBC-based test has reached clinical use. The…

定量方法 · 定量生物学 2026-05-19 Amio Pronoy Das Ritwik , Yamin Mansur , Jingcheng Ma

In the era of growing interest in healthy buildings and smart homes, the importance of sustainable, health conscious indoor environments is paramount. Smart tools, especially VOC sensors, are crucial for monitoring indoor air quality, yet…

Breathing is one of the most important body functions because it provides it with oxygen, which is vital for energy production. In addition, the removal of carbon dioxide actively regulates the acid-base level, which is essential for the…

信号处理 · 电气工程与系统科学 2022-10-18 Janosch Kunczik , Kerstin Hubbermann , Lucas Mösch , Andreas Follmann , Michael Czaplik , Carina Barbosa Pereira

Research for possible biosignature gases on habitable exoplanet atmosphere is accelerating. We add isoprene, C5H8, to the roster of biosignature gases. We found that formation of isoprene geochemical formation is highly thermodynamically…

地球与行星天体物理 · 物理学 2021-04-09 Zhuchang Zhan , Sara Seager , Janusz Jurand Petkowski , Clara Sousa-Silva , Sukrit Ranjan , Jingcheng Huang , William Bains

Human skin is a region of high metabolic activity where a rich variety of biomarkers are secreted from the stratum corneum. The skin is a constant source of volatile organic compounds (VOCs) derived from skin glands and resident microbiota.…

其他定量生物学 · 定量生物学 2020-08-03 Emer Duffy , Aoife Morrin

We develop a simple three compartment model based on mass balance equations which quantitatively describes the dynamics of breath methane concentration profiles during exercise on an ergometer. With the help of this model it is possible to…

Volatile organic compounds emitted by a human body form a chemical signature capable of providing invaluable information on the physiological status of an individual and, thereby, could serve as signs-of-life for detecting victims after…

其他定量生物学 · 定量生物学 2015-04-24 Pawel Mochalski , Karl Unterkofler , Gerald Teschl , Anton Amann

The nonlinear features of the relationships between concentrations of aerosol and volatile organic compounds (VOC) and oxides of nitrogen (NOx) in urban environments are derived directly from data of long-term routine measurements of NOx,…

大气与海洋物理 · 物理学 2020-11-04 Igor B. Konovalov
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