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High-resolution X-ray observations have revealed cavities and `cold fronts' with sharp edges in temperature, density, and metallicity within galaxy clusters. Their presence poses a puzzle since these features are not expected to be…
While propagating in transparent media, near-infrared multi-terawatt (TW) laser beams break up in a multitude of filaments of typically 100-200 um diameter with peak intensities as high as 10 to 100~TW/cm$^{2}$. We observe a phase…
Analysis of three-dimensional biological samples is critical to understanding tissue function and the mechanisms of disease. Many chronic conditions, like neurodegenerative diseases and cancers, correlate with complex tissue changes that…
A hollow cylindrical micron-scale structure is proposed to enhance and manipulate the laser plasma interaction. It is shown through 3-D particle-in-cell simulations that the incident laser pulse intensity is enhanced within the tube. A…
We use optical trapping to continuously bend an isolated microtubule while simultaneously measuring the applied force and the resulting filament strain, thus allowing us to determine its elastic properties over a wide range of applied…
We report an experimental and numerical investigation of the fragmentation mechanisms of micrometer-sized metal droplet irradiated by ultrashort laser pulses. The results of the experiment show that the fast one-side heating of such a…
Understanding the shell rheology of ultrasound contrast agent microbubbles is vital for anticipating their bioeffects in clinical practice. Past studies using sophisticated acoustic and optical techniques have made enormous progress in this…
A numerical hydrodynamic study of femtosecond laser ablation is presented. A detailed analysis of material decomposition is performed using a thermodynamically complete equation of state with separate stable and metastable phase states and…
A simple, yet effective method of controlling the size and size distributions of nanoparticles produced as a result of laser ablation of target material is presented. The method employs the presence of physical boundaries on either sides of…
Controlling the dynamics of topologically protected spin objects by all optical means promises enormous potential for future spintronic applications. Excitation of bubbles and skyrmions in ferrimagnetic [Fe(0.35 nm)/Gd(0.40 nm)]$_{160}$…
Stiff and dense fibrin networks in chronic blood clots impede drug penetration and distribution into the clot core, limiting the efficacy of thrombolytic therapies. Acoustic cavitation of microbubbles is a promising strategy to enhance drug…
The dynamics of bubble clouds induced by high-intensity focused ultrasound are investigated in a regime where the cloud size is similar to the ultrasound wavelength. High-speed images show that the cloud is asymmetrical; the bubbles nearest…
Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…
The spatio-temporal dynamics of separation bubbles induced to form in a fully-developed turbulent boundary layer (with Reynolds number based on momentum thickness of the boundary layer of 490) over a flat plate are studied via direct…
Many experiments in biological and medical sciences currently use multiphoton microscopy as a core imaging technique. To date, solid-state lasers are most commonly used as excitation beam sources. However, the most demanding applications…
We report a detailed experimental characterization of the periodic bubbling regimes that take place in an axisymmetric air-water jet when the inner air stream is forced by periodic modulations of the pressure at the upstream air feeding…
Ablation of Cu and Al targets has been performed with 170 fs laser pulses in the intensity range of 10^12-10^14 W/cm^2. We compare the measured removal depth with 1D hydrodynamic simulations. The electron-ion temperature decoupling is taken…
A new technique for the separation of macromolecules is proposed and investigated. A thin mesh with pores comparable to the radius of gyration of a free chain is used to filter chains according to their length. Without a field it has…
In the past two decades, tremendous efforts have been exerted to understand and control the delivery of ultrashort laser pulses into various types of transparent materials ranging from glass and crystal to polymer and even bio-materials.…
The shock-boundary layer interaction over the convex wall of a supersonic turbine vane is studied with a focus on extreme separation bubble events and the interplay between the bubble, streaks, and streamwise vortices. The present analysis…