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相关论文: Molecular imaging with X-ray free electron lasers:…

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Coherent diffraction imaging (CDI) of single molecules at atomic resolution is a major goal for the x-ray free electron lasers (XFELs). However, during an imaging pulse, the fast laser-induced ionization may strongly affect the recorded…

介观与纳米尺度物理 · 物理学 2015-06-05 Zoltan Jurek , Robert Thiele , Beata Ziaja , Robin Santra

X-ray scattering experiments using Free Electron Lasers (XFELs) are a powerful tool to determine the molecular structure and function of unknown samples (such as COVID-19 viral proteins). XFEL experiments are a challenge to computing in two…

X-ray Free Electron Lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit is the delivery of samples to the X-ray interaction…

Attosecond pulses of coherent extreme ultraviolet (XUV) light are instrumental for investigating subatomic dynamics and can be produced using a free-electron laser (FEL). It has been suggested that an optical FEL, which employs a laser…

等离子体物理 · 物理学 2025-07-09 Michael J. Quin , Antonino Di Piazza , Çağrı Erciyes , Christoph H. Keitel , Matteo Tamburini

Typical parameters of electron bunches available now in undulator X-ray FELs enable generation of induced radiation in crystal-based X-ray VFEL. An important peculiarity of an undulator X-ray FEL is electron bunch spatial modulation with…

等离子体物理 · 物理学 2024-07-25 V. G. Baryshevsky

Modern microscopy techniques are aimed at imaging an individual molecule at atomic resolution. Here we show that low-energy electrons with kinetic energies of 50-250 eV offer a possibility of overcome the problem of radiation damage, and…

生物物理 · 物理学 2013-05-09 Tatiana Latychevskaia , Jean-Nicolas Longchamp , Conrad Escher , Hans-Werner Fink

The successful operation of the hard x-ray self-seeding experiment at the LCLS opens the era of fully coherent hard x-ray free electron lasers (FELs). However, the shot-to-shot radiation fluctuation is still a serious issue. In this paper,…

加速器物理 · 物理学 2013-05-07 Haixiao Deng , Chao Feng

An outstanding question in X-ray single particle imaging experiments has been the feasibility of imaging sub 10-nm-sized biomolecules under realistic experimental conditions where very few photons are expected to be measured in a single…

The possibility of performing the experimental research in the field of fundamental physics based on the unique instrument -- European X-ray Free Electron Laser (E-XFEL) is considered in this paper. The calculations of the reaction $\gamma…

高能物理 - 实验 · 物理学 2020-03-16 A. N. Popov , S. V. Bobashev , N. O. Bezverkhnii , A. A. Sorokin

Femtosecond transient soft X-ray Absorption Spectroscopy (XAS) is a very promising technique that can be employed at X-ray Free Electron Lasers (FELs) to investigate out-of-equilibrium dynamics for material and energy research. Here we…

When atoms and molecules are irradiated by an x-ray free-electron laser (XFEL), they are highly ionized via a sequence of one-photon ionization and relaxation processes. To describe the ionization dynamics during XFEL pulses, a rate…

原子物理 · 物理学 2013-03-13 Sang-Kil Son , Robin Santra

X-ray free-electron lasers (XFELs) are renowned for their high brightness, significantly impacting biology, chemistry, and nonlinear X-ray optics. However, current XFELs are large, expensive, and exhibit significant shot-to-shot…

原子物理 · 物理学 2024-12-17 Shuang Li

Delivering sub-micrometer particles to an intense x-ray focus is a crucial aspect of single-particle diffractive-imaging experiments at x-ray free-electron lasers. Enabling direct visualization of sub-micrometer aerosol particle streams…

Two-color X-ray imaging with Free Electron Laser pulses offers a powerful approach for probing ultrafast structural dynamics in nanoscale systems, combining (near-)atomic spatial resolution with femtosecond temporal precision. The first…

In this paper we describe a measurement technique capable of resolving femtosecond X-ray pulses from XFEL facilities. Since these ultrashort pulses are themselves the shortest event available, our measurement strategy is to let the X-ray…

加速器物理 · 物理学 2010-01-21 Gianluca Geloni , Vitali Kocharyan , Evgeni Saldin

Single particle imaging (SPI) at X-ray free electron lasers (XFELs) is a technique to determine the 3D structure of nanoscale objects like biomolecules from a large number of diffraction patterns of copies of these objects in random…

图像与视频处理 · 电气工程与系统科学 2022-10-20 Abhishek Mall , Kartik Ayyer

Dark field X-ray microscopy (DXFM) can visualize microstructural distortions in bulk crystals. Using the femtosecond X-ray pulses generated by X-ray free-electron lasers (XFEL), DFXM can achieve sub-{\mu}m spatial resolution and <100 fs…

Structural studies of biological macromolecules are severely limited by radiation damage. Traditional crystallography curbs the effects of damage by spreading damage over many copies of the molecule of interest. X-ray lasers, such as the…

The advent of accelerator-driven free-electron lasers (FEL) has opened new avenues for high-resolution structure determination via diffraction methods that go far beyond conventional x-ray crystallography methods. These techniques rely on…

With the rapid development of short-pulse intense laser sources, studies of matter under extreme irradiation conditions enter further unexplored regimes. In addition, an application of X-ray Free- Electron Lasers (XFELs), delivering intense…