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Organisms move through the world by changing their shape, and here we explore the mapping from shape space to movements in the nematode C. elegans as it crawls on a planar agar surface. We characterize the statistics of the trajectories…

神经元与认知 · 定量生物学 2016-01-05 Greg J Stephens , Bethany Johnson-Kerner , William Bialek , William S Ryu

The neural dynamics of the nematode C. elegans are experimentally low-dimensional and correspond to discrete behavioral states, where previous modeling work has found neural proxies for some of these states. Experimental results further…

神经元与认知 · 定量生物学 2015-09-04 James Kunert , Eli Shlizerman , Andrew Walker , J. Nathan Kutz

To survive in ever-changing environments, living organisms need to continuously combine the ongoing external inputs they receive, representing present conditions, with their dynamical internal state, which includes influences of past…

神经元与认知 · 定量生物学 2024-02-09 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

Many dynamical systems found in biology, ranging from genetic circuits to the human brain to human social systems, are inherently computational. Although extensive research has explored their resulting functions and behaviors, the…

神经元与认知 · 定量生物学 2025-04-15 Junang Li , Andrew M. Leifer , David H. Wolpert

Despite recent interest in reconstructing neuronal networks, complete wiring diagrams on the level of individual synapses remain scarce and the insights into function they can provide remain unclear. Even for Caenorhabditis elegans, whose…

神经元与认知 · 定量生物学 2011-02-07 Lav R. Varshney , Beth L. Chen , Eric Paniagua , David H. Hall , Dmitri B. Chklovskii

We introduce MABe22, a large-scale, multi-agent video and trajectory benchmark to assess the quality of learned behavior representations. This dataset is collected from a variety of biology experiments, and includes triplets of interacting…

Advanced volumetric imaging methods and genetically encoded activity indicators have permitted a comprehensive characterization of whole brain activity at single neuron resolution in \textit{Caenorhabditis elegans}. The constant motion and…

定量方法 · 定量生物学 2022-10-12 Yuxiang Wu , Shang Wu , Xin Wang , Chengtian Lang , Quanshi Zhang , Quan Wen , Tianqi Xu

A central problem of neuroscience involves uncovering the principles governing the organization of nervous systems which ensure robustness in brain development. The nematode Caenorhabditis elegans provides us with a model organism for…

神经元与认知 · 定量生物学 2020-07-01 Anand Pathak , Nivedita Chatterjee , Sitabhra Sinha

Dynamical systems in the life sciences are often composed of complex mixtures of overlapping behavioral regimes. Cellular subpopulations may shift from cycling to equilibrium dynamics or branch towards different developmental fates. The…

机器学习 · 计算机科学 2025-10-13 Nathan Quiblier , Roy Friedman , Matthew Ricci

Multi-organ segmentation is a critical yet challenging task due to complex anatomical backgrounds, blurred boundaries, and diverse morphologies. This study introduces the Gradient-aware Adaptive Momentum Evolution Deep Snake (GAMED-Snake)…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Ruicheng Zhang , Haowei Guo , Zeyu Zhang , Puxin Yan , Shen Zhao

The nematode Caenorhabditis elegans, with information on neural connectivity, three-dimensional position and cell linage provides a unique system for understanding the development of neural networks. Although C. elegans has been widely…

生物物理 · 物理学 2011-01-17 Sreedevi Varier , Marcus Kaiser

Multi-view pose estimation is essential for quantifying animal behavior in scientific research, yet current methods struggle to achieve accurate tracking with limited labeled data and suffer from poor uncertainty estimates. We address these…

计算机视觉与模式识别 · 计算机科学 2025-10-14 Lenny Aharon , Keemin Lee , Karan Sikka , Selmaan Chettih , Cole Hurwitz , Liam Paninski , Matthew R Whiteway

Dissipative environments are ubiquitous in nature, from microscopic swimmers in low-Reynolds-number fluids to macroscopic animals in frictional media. In this study, motivated by various behaviours of {\it Caenorhabditis elegans} during…

适应与自组织系统 · 物理学 2025-04-15 Kenta Ishimoto , Clément Moreau , Johann Herault

Semi-supervised learning has been employed to alleviate the need for extensive labeled data for histopathology image segmentation, but existing methods struggle with noisy pseudo-labels due to ambiguous gland boundaries and morphological…

计算机视觉与模式识别 · 计算机科学 2025-09-18 Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Thien Nguyen , Daisuke Kihara , Tianyang Wang , Xingjian Li , Min Xu

With the accumulation of big data of CME observations by coronagraphs, automatic detection and tracking of CMEs has proven to be crucial. The excellent performance of convolutional neural network in image classification, object detection…

太阳与恒星天体物理 · 物理学 2019-09-25 Pengyu Wang , Yan Zhang , Li Feng , Hanqing Yuan , Yuan Gan , Shuting Li , Lei Lu , Beili Ying , Weiqun Gan , Hui Li

To establish the relationship between locomotory behavior and dynamics of neural circuits in the nematode C. elegans we combined molecular and theoretical approaches. In particular, we quantitatively analyzed the motion of C. elegans with…

神经元与认知 · 定量生物学 2008-06-10 Jan Karbowski , Gary Schindelman , Chris J. Cronin , Adeline Seah , Paul W. Sternberg

Gait encodes rich biometric and behavioural information, yet leveraging the manner of walking to infer psychological traits remains a challenging and underexplored problem. We introduce a hierarchical Multi-Stage Mixture of Movement Experts…

计算机视觉与模式识别 · 计算机科学 2025-10-08 Andy Cǎtrunǎ , Adrian Cosma , Emilian Rǎdoi

This study introduces an artificial neural network (ANN) for image classification task, inspired by the aversive olfactory learning circuits of the nematode Caenorhabditis elegans (C. elegans). Despite the remarkable performance of ANNs in…

神经与进化计算 · 计算机科学 2024-09-13 Xuebin Wang , Chunxiuzi Liu , Meng Zhao , Ke Zhang , Zengru Di , He Liu

Movement is fundamental to life, shaping population dynamics, biodiversity patterns, and ecosystem structure. Recent advances in tracking technology have enabled fundamental questions about movement to be tackled, leading to the development…

Alignment between human brain networks and artificial models has become an active research area in vision science and machine learning. A widely adopted approach is identifying "metamers," stimuli physically different yet perceptually…

机器学习 · 计算机科学 2025-09-25 Mina Kamao , Hayato Ono , Ayumu Yamashita , Kaoru Amano , Masataka Sawayama