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Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. Previous models of run and tumble chemotaxis neglect one or more features of the…

定量方法 · 定量生物学 2007-06-26 J. T. Locsei

Chemotaxis of the bacterium Escherichia coli is well understood in shallow chemical gradients, but its swimming behavior remains difficult to interpret in steep gradients. By focusing on single-cell trajectories from simulations, we…

细胞行为 · 定量生物学 2018-02-14 Gabriele Micali , Remy Colin , Victor Sourjik , Robert G. Endres

The bacterium E.Coli swims in a zig-zag manner, in a series of straight runs and tumbles occurring alternately, with the run-durations dependent on the local spatial gradient of chemo-attractants/repellants. This enables the organism to…

细胞行为 · 定量生物学 2008-12-31 Melissa Reneaux , Manoj Gopalakrishnan

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. This paper presents calculations of the chemotactic drift velocity vd (the mean…

定量方法 · 定量生物学 2008-04-16 J. T. Locsei , T. J. Pedley

The bacterium E. coli maneuvers itself to regions with high chemoattractant concentrations by performing two stereotypical moves: `runs', in which it moves in near straight lines, and `tumbles', in which it does not advance but changes…

细胞行为 · 定量生物学 2007-11-29 Yariv Kafri , Rava Azeredo da Silveira

We study single cell E.coli chemotaxis in a spatio-temporally varying attractant environment. Modeling the attractant concentration in the form of a traveling sine wave, we measure in our simulations, the chemotactic drift velocity of the…

细胞行为 · 定量生物学 2025-06-06 Shobhan Dev Mandal , Sakuntala Chatterjee

Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. This process is characterised by a drift velocity that depends non-linearly on the concentration of chemical species and its…

流体动力学 · 物理学 2026-05-07 Adam Gargasson , Julien Bouvard , Carine Douarche , Peter Mergaert , Harold Auradou

Bacteria such as Escherichia coli move about in a series of runs and tumbles: while a run state (straight motion) entails all the flagellar motors spinning in counterclockwise mode, a tumble is caused by a shift in the state of one or more…

定量方法 · 定量生物学 2020-01-08 C. S. Renadheer , Ushasi Roy , Manoj Gopalakrishnan

Bacteria such as Escherichia coli (E. coli) exhibit biased motion if kept in a spatially non-uniform chemical environment. Here, we bring out unique time-dependent characteristics of bacterial chemotaxis, in response to a diffusing spatial…

Most of our understanding of bacterial chemotaxis comes from studies of Escherichia coli. However, recent evidence suggests significant departures from the E. coli paradigm in other bacterial species. This variation may stem from different…

细胞行为 · 定量生物学 2015-03-27 Martin Godány , Bhavin S. Khatri , Richard A. Goldstein

{\sl Escherichia coli} ({\sl E. coli}) bacteria govern their trajectories by switching between running and tumbling modes as a function of the nutrient concentration they experienced in the past. At short time one observes a drift of the…

统计力学 · 物理学 2011-12-08 Sakuntala Chatterjee , Rava Azeredo da Silveira , Yariv Kafri

Adaptation of the chemotaxis sensory pathway of the bacterium Escherichia coli is integral for detecting chemicals over a wide range of background concentrations, ultimately allowing cells to swim towards sources of attractant and away from…

细胞行为 · 定量生物学 2015-05-18 Diana Clausznitzer , Olga Oleksiuk , Linda Lovdok , Victor Sourjik , Robert G. Endres

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemotactic responses to form millimeter-sized condensates…

生物物理 · 物理学 2025-05-02 Nir Livne , Ady Vaknin , Oded Agam

Bacterial motility, and in particular repulsion or attraction towards specific chemicals, has been a subject of investigation for over 100 years, resulting in detailed understanding of bacterial chemotaxis and the corresponding sensory…

生物物理 · 物理学 2022-06-08 Jerko Rosko , Vincent Martinez , Wilson Poon , Teuta Pilizota

Growing living cultures of Escherichia coli bacteria were investigated using real-time in situ rheology and rheo-imaging measurements. In the early stages of growth (lag phase), and when subjected to a constant stationary shear, the…

生物物理 · 物理学 2016-12-21 R. Portela , P. Patrício , P. L. Almeida , R. G. Sobral , J. M. Franco , C. R. Leal

Bacterial chemotaxis for E.coli is controlled by methylation of chemoreceptors, which in a biochemical pathway regulates the concentration of the CheY-P protein that finally controls the tumbling rate. As a consequence, the tumbling rate…

软凝聚态物质 · 物理学 2025-04-23 Manuel Mayo , Rodrigo Soto

Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find…

流体动力学 · 物理学 2015-11-04 A. E. Patteson , A. Gopinath , M. Goulian , P. E. Arratia

Flagellated bacteria, such as Escherichia coli, perform directed motion in gradients of concentration of attractants and repellents in a process called chemotaxis. The E. coli chemotaxis signaling pathway is a model for signal transduction,…

生物物理 · 物理学 2015-03-11 Anne-Florence Bitbol , Ned S. Wingreen

Bacteria can chemotactically migrate up attractant gradients by controlling run-and-tumble motility patterns. In addition to this well-known chemotactic behaviour, several soil and marine bacterial species perform chemokinesis: they adjust…

Bacterial chemotaxis is one of the most extensively studied adaptive responses in cells. Many bacteria are able to bias their apparently random motion to produce a drift in the direction of the increasing chemoattractant concentration. It…

软凝聚态物质 · 物理学 2018-02-07 E. V. Pankratova , A. I. Kalyakulina , M. I. Krivonosov , S. Denisov , K. M. Taute , V. Yu. Zaburdaev
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