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Deep neural network-based architectures give promising results in various domains including pattern recognition. Finding the optimal combination of the hyper-parameters of such a large-sized architecture is tedious and requires a large…

计算机视觉与模式识别 · 计算机科学 2020-03-17 Animesh Singh , Sandip Saha , Ritesh Sarkhel , Mahantapas Kundu , Mita Nasipuri , Nibaran Das

The phenomenon of gene conservation is an interesting evolutionary problem related to speciation and adaptation. Conserved genes are acted upon in evolution in a way that preserves their function despite other structural and functional…

基因组学 · 定量生物学 2008-07-23 Bradly J. Alicea , Marcela A. Carvallo-Pinto , Jorge L. M. Rodrigues

Applying a method to reconstruct a phylogenetic tree from random data provides a way to detect whether that method has an inherent bias towards certain tree `shapes'. For maximum parsimony, applied to a sequence of random 2-state data, each…

种群与进化 · 定量生物学 2014-06-03 Mareike Fischer , Michelle Galla , Lina Herbst , Mike Steel

Given a well-behaved neural network, is possible to identify its parent, based on which it was tuned? In this paper, we introduce a novel task known as neural lineage detection, aiming at discovering lineage relationships between parent and…

计算机视觉与模式识别 · 计算机科学 2024-06-18 Runpeng Yu , Xinchao Wang

Causal discovery in multi-omic datasets is crucial for understanding the bigger picture of gene regulatory mechanisms, but remains challenging due to high dimensionality, differentiation of direct from indirect relationships, and hidden…

基因组学 · 定量生物学 2025-05-23 Stephen Asiedu , David Watson

Computers play a crucial role in modern ancestry management, they are used to collect, store, analyze, sort and display genealogical data. However, current applications do not take into account the kinship structure of a natural language.…

数据库 · 计算机科学 2018-07-03 Evgeniy Gryaznov

This note presents a simple and effective variation of genetic algorithm (GA) for solving RCPSP, denoted as 2-Phase Genetic Algorithm (2PGA). The 2PGA implements GA parent selection in two phases: Phase-1 includes the best current solutions…

神经与进化计算 · 计算机科学 2025-09-04 D. Sun , S. Zhou

We propose a genetic algorithm (GA) for hyperparameter optimization of artificial neural networks which includes chromosomal crossover as well as a decoupling of parameters (i.e., weights and biases) from hyperparameters (e.g., learning…

神经与进化计算 · 计算机科学 2019-01-15 Aaron Vose , Jacob Balma , Alex Heye , Alessandro Rigazzi , Charles Siegel , Diana Moise , Benjamin Robbins , Rangan Sukumar

Constraint-based causal discovery from limited data is a notoriously difficult challenge due to the many borderline independence test decisions. Several approaches to improve the reliability of the predictions by exploiting redundancy in…

机器学习 · 计算机科学 2017-01-27 Sara Magliacane , Tom Claassen , Joris M. Mooij

Populations of isogenic embryonic stem cells or clonal bacteria often exhibit extensive phenotypic heterogeneity which arises from stochastic intrinsic dynamics of cells. The internal state of the cell can be transmitted epigenetically in…

种群与进化 · 定量生物学 2016-02-17 Sahand Hormoz , Nicolas Desprat , Boris I. Shraiman

Branch and Bound (B&B) is the exact tree search method typically used to solve Mixed-Integer Linear Programming problems (MILPs). Learning branching policies for MILP has become an active research area, with most works proposing to imitate…

机器学习 · 计算机科学 2021-06-04 Giulia Zarpellon , Jason Jo , Andrea Lodi , Yoshua Bengio

The application of Genetic Programming to the discovery of empirical laws is often impaired by the huge size of the search space, and consequently by the computer resources needed. In many cases, the extreme demand for memory and CPU is due…

人工智能 · 计算机科学 2016-08-16 Alain Ratle , Michèle Sebag

Biclustering numerical data became a popular data-mining task in the beginning of 2000's, especially for analysing gene expression data. A bicluster reflects a strong association between a subset of objects and a subset of attributes in a…

数据结构与算法 · 计算机科学 2011-11-15 Mehdi Kaytoue , Sergei O. Kuznetsov , Juraj Macko , Wagner Meira , Amedeo Napoli

Graphs can be used to effectively represent complex data structures. Learning these irregular data in graphs is challenging and still suffers from shallow learning. Applying deep learning on graphs has recently showed good performance in…

机器学习 · 计算机科学 2020-09-16 Thosini Bamunu Mudiyanselage , Xiujuan Lei , Nipuna Senanayake , Yanqing Zhang , Yi Pan

In this paper, we employ genetic algorithms to explore the landscape of type IIB flux vacua. We show that genetic algorithms can efficiently scan the landscape for viable solutions satisfying various criteria. More specifically, we consider…

高能物理 - 理论 · 物理学 2020-01-08 Alex Cole , Andreas Schachner , Gary Shiu

Association Rule Mining is a machine learning method for discovering the interesting relations between the attributes in a huge transaction database. Typically, algorithms for Association Rule Mining generate a huge number of association…

神经与进化计算 · 计算机科学 2021-04-19 Iztok Fister , Iztok Fister

An important problem in evolutionary genomics is to investigate whether a certain trait measured on each sample is associated with the sample phylogenetic tree. The phylogenetic tree represents the shared evolutionary history of the samples…

种群与进化 · 定量生物学 2024-07-22 Julie Zhang , Gabriel A. Preising , Molly Schumer , Julia A. Palacios

Identification of disease genes, which are a set of genes associated with a disease, plays an important role in understanding and curing diseases. In this paper, we present a biomedical knowledge graph designed specifically for this…

Motivated by the important problem of detecting association between genetic markers and binary traits in genome-wide association studies, we present a novel Bayesian model that establishes a hierarchy between markers and genes by defining…

应用统计 · 统计学 2016-06-22 Ian Johnston , Timothy Hancock , Hiroshi Mamitsuka , Luis Carvalho

Reliability is one of the important measures of how well the system meets its design objective, and mathematically is the probability that a system will perform satisfactorily for at least a given period of time. When the system is…

物理与社会 · 物理学 2014-12-16 Ho Tat Lam , Kwok Yip Szeto