相关论文: Ex-vivo detection of neural events using THz BioME…
Electromagnetic frequencies up to a few terahertz (THz) can yield real-time and noninvasive measurements on biological matter. Unfortunately, strong absorption in aqueous solutions and low spatial resolution return difficult free-space…
This work focuses on the fabrication and use of a Biological Micro-ElectroMechanical System (BioMEMS) for TeraHertz (THz) detection and characterization of enzymatic catalysis reactions. The fluidic microdevice was fabricated using…
Nucleic acid-based electrochemical sensors (NBEs) have emerged as a promising approach to continuous molecular monitoring in vivo. NBEs consist of electrically conducting gold surfaces coated with self-assembled monolayers of a mixture of…
We introduce a novel electro-optomechanic neural sensor for realizing ultra-compact neural recording probes that can detect and relay electrophysiology signals from within neural tissue. This technology addresses outstanding challenges…
Terahertz (THz) waves have been significantly developed in the last fifteen years because of their great potential for applications in industrial and scientific communities1,2. The unique properties of THz waves as transparency for numerous…
Objective: We present magnetomyograms (MMG) of TMS-evoked movement in a human hand, together with a simultaneous surface electromyograph (EMG) and electroencephalograph (EEG) data. Approach: We combined TMS with non-contact magnetic…
We present a method for the measurements of the tetrahertz (THz) resonance response of DNA oligonucleotides deposited on a silicon nanosandwich (SNS). It is shown that the SNS device can be used to generate a THz resonance response within…
The terahertz (THz) spectral domain offers a myriad of applications spanning chemical spectroscopy, medicine, security and imaging[1]. It has also recently become a playground for fundamental studies of light-matter interactions [2-6]. THz…
Terahertz time-domain spectroscopy (THz-TDS) is a non-invasive, non-contact and label-free technique for biological and chemical sensing as THz-spectra is less energetic and lies in the characteristic vibration frequency regime of proteins…
An important tool in the investigation of the early stages of neurodegenerative disease is the study of dissected living tissue from the brain of an animal model. Such investigations allow the physical structure of individual neurons and…
Intracellular processes triggered by neural activity include changes in ionic concentrations, protein release, and synaptic vesicle cycling. These processes play significant roles in neurological disorders. The beneficial effects of brain…
Trigeminal neuralgia (TN) is the most common neuropathic disorder; however, its pathogenesis remains unclear. A prevailing theory suggests that nitric oxide (NO) may induce nerve compression and irritation via vascular dilation, thereby…
Nanoelectromechanical systems (NEMSs) are emerging nanoscale elements at the crossroads between mechanics, optics and electronics, with significant potential for actuation and sensing applications. The reduction of dimensions compared to…
We present an experimental instrument that performs laboratory-based gas-phase Terahertz Desorption Emission Spectroscopy (THz-DES) experiments in support of astrochemistry. The measurement system combines a terahertz heterodyne radiometer…
Background and Objective: Transcranial temporal interference stimulation (tTIS) is a promising non-invasive brain stimulation technique in which interference between electrical current fields extends the possibilities of electrical brain…
Biological impedance (BioZ) is an information-packed modality that allows for non-invasive monitoring of health and emotional state. Currently, most research involving tissue impedance is based on bulky or fixed-purpose hardware, which…
Bioanalytical THz sensing techniques have proven to be an interesting and viable tool for the label-free detection and analysis of biomolecules. However, a major challenge for THz bioanalytics is to perform investigations in the native…
In recent years, the progress on low temperature detector technologies has allowed design of large scale experiments aiming at pushing down the sensitivity on the neutrino mass below 1\,eV. Even with outstanding performances in both energy…
We propose a biosensor based on the change of terahertz (THz) dielectric response when a biotarget binds to a probe. The feasibility of this biosensor is examined by studying the change of THz transmission for thin films of heme proteins…
The tumor microenvironment (TME) features distinct hallmarks, including acidosis, hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial targets for early cancer biomarker detection, tumor diagnosis,…