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We present a mean-field dynamical theory for single semiflexible polymers which can precisely capture, without fitting parameters, recent fluorescence correlation spectroscopy results on single monomer kinetics of DNA strands in solution.…

软凝聚态物质 · 物理学 2009-10-19 Michael Hinczewski , Roland R. Netz

We derive a general mean-field theory of inhomogeneous polymer dynamics; a theory whose form has been speculated and widely applied, but not heretofore derived. Our approach involves a functional integral representation of a…

软凝聚态物质 · 物理学 2015-06-18 Glenn H. Fredrickson , Henri Orland

We present a novel method to investigate the dynamics of a single semiflexible polymer, subject to anisotropic friction in a viscous fluid. In contrast to previous approaches, we do not rely on a discrete bead-rod model, but introduce a…

生物大分子 · 定量生物学 2009-11-13 Tobias Munk , Oskar Hallatschek , Chris H. Wiggins , Erwin Frey

Spurred by an experimental controversy in the literature, we investigate the end-monomer dynamics of semiflexible polymers through Brownian hydrodynamic simulations and dynamic mean-field theory. Precise experimental observations over the…

软凝聚态物质 · 物理学 2009-06-20 Michael Hinczewski , Xaver Schlagberger , Michael Rubinstein , Oleg Krichevsky , Roland R. Netz

We analyze the nonequilibrium dynamics of single inextensible semiflexible biopolymers as stretching forces are applied at the ends. Based on different (contradicting) heuristic arguments, various scaling laws have been proposed for the…

软凝聚态物质 · 物理学 2007-09-17 B. Obermayer , O. Hallatschek , E. Frey , K. Kroy

We describe a simple meanfield variational approach to study a number of properties of intrinsically stiff chains which are appropriate models for a large class of biopolymers. We present the calculation of the distribution of end-to-end…

软凝聚态物质 · 物理学 2008-02-03 D. Thirumalai , B. -Y. Ha

Conformations of a single semiflexible polymer chain dissolved in a low molecular weight liquid crystalline solvents (nematogens) are examined by using a mean field theory. We takes into account a stiffness and partial orientational…

软凝聚态物质 · 物理学 2009-11-07 Akihiko Matsuyama

Single-molecule force-extension experiments have allowed quantitative measurements of the mechanical responses of biomolecules to applied forces explaining their roles in key biological functions. Electrophoretic stretching of charged…

软凝聚态物质 · 物理学 2024-02-21 Ananya Mondal , Greg Morrison

Based on the wormlike chain model, a coarse-grained description of the nonlinear dynamics of a weakly bending semiflexible polymer is developed. By means of a multiple scale perturbation analysis, a length-scale separation inherent to the…

软凝聚态物质 · 物理学 2007-12-04 Oskar Hallatschek , Erwin Frey , Klaus Kroy

The entropic effects of anchored polymers on biomembranes are studied using simulations of a meshless membrane model combined with anchored linear polymer chains. The bending rigidity and spontaneous curvature are investigated for anchored…

软凝聚态物质 · 物理学 2015-02-18 Hao Wu , Hayato Shiba , Hiroshi Noguchi

In Part I of this contribution, a systematic coarse-grained description of the dynamics of a weakly-bending semiflexible polymer was developed. Here, we discuss analytical solutions of the established deterministic partial…

软凝聚态物质 · 物理学 2007-12-04 Oskar Hallatschek , Erwin Frey , Klaus Kroy

We investigate active electrolytes within the mean-field level of description. The focus is on how the double-layer structure of passive, thermalized charges is affected by active dynamics of all constituting ions. One feature of active…

软凝聚态物质 · 物理学 2018-05-23 Derek Frydel , Rudolf Podgornik

Loops undergoing thermal fluctuations are prevalent in nature. Ring-like or cross-linked polymers, cyclic macromolecules, and protein-mediated DNA loops all belong to this category. Stability of these molecules are generally described in…

计算物理 · 物理学 2016-04-27 James T. Waters , Harold D. Kim

The non-equilibrium structural and dynamical properties of semiflexible polymers confined to two dimensions are investigated by molecular dynamics simulations. Three different scenarios are considered: The force-extension relation of…

软凝聚态物质 · 物理学 2013-01-08 A. Lamura , R. G. Winkler

Thermal fluctuations of microtubules (MTs) and other cytoskeletal filaments govern to a great extent the complex rheological properties of the cytoskeleton in eukaryotic cells. In recent years, much effort has been put into capturing the…

软凝聚态物质 · 物理学 2011-10-26 Sander L. Poelert , Harrie H. Weinans , Amir A. Zadpoor

The properties of semiflexible polymers tethered by one end to an impenetrable wall and exposed to oscillatory shear flow are investigated by mesoscale simulations. A polymer, confined in two dimensions, is described by a linear bead-spring…

软凝聚态物质 · 物理学 2021-12-14 Antonio Lamura , Roland G. Winkler , Gerhard Gompper

We study the mechanical properties of semiflexible polymers when the contour length of the polymer is comparable to its persistence length. We compute the exact average end-to-end distance and shape of the polymer for different boundary…

生物大分子 · 定量生物学 2013-05-29 Yuko Hori , Ashok Prasad , Jane' Kondev

The dynamical response of a tethered semiflexible polymer with self-attractive interactions and subjected to an external force field is numerically investigated by varying stiffness and self-interaction strength. The chain is confined in…

软凝聚态物质 · 物理学 2022-11-09 A. Lamura

The linear viscoelastic response of single semiflexible polymer chains in the infinite-dilution limit is studied using Brownian dynamics simulations of coarse-grained bead-spring chains. The springs obey the FENE-Fraenkel force law, a…

软凝聚态物质 · 物理学 2026-03-03 Amit Varakhedkar , P. Sunthar , J. Ravi Prakash

The longitudinal response of single semiflexible polymers to sudden changes in externally applied forces is known to be controlled by the propagation and relaxation of backbone tension. Under many experimental circumstances, realized, e.g.,…

软凝聚态物质 · 物理学 2011-02-25 Florian Thüroff , Benedikt Obermayer , Erwin Frey
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