相关论文: How informative are spatial CA3 representations es…

Hippocampal CA3 is crucial for the formation of long-term associative memory. It has a heavily recurrent connectivity, and memories are thought to be stored as memory engrams in the CA3. However, despite its importance for memory storage…

Efficient pattern separation in dentate gyrus plays an important role in storing information in the hippocampus. Current knowledge of the structure and function of the hippocampus, entorhinal cortex and dentate gyrus, in pattern separation…

Functional brain graphs are often characterized with separate graph-theoretic or spectral descriptors, overlooking how these properties covary and partially overlap across brains and conditions. We anticipate that dense, weighted functional…

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Astrocytes, the most abundant type of glial cell, play a fundamental role in memory. Despite most hippocampal synapses being contacted by an astrocyte, there are no current theories that explain how neurons, synapses, and astrocytes might…

The vertebrate hippocampus is believed to use recurrent connectivity in area CA3 to support episodic memory recall from partial cues. This brain area also contains place cells, whose location-selective firing fields implement maps…

The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…

Hippocampal formation (HF) can rapidly adapt to varied environments and build flexible working memory (WM). To mirror the HF's mechanism on generalization and WM, we propose a model named Generalization and Associative Temporary Encoding…

We are concerned about the main encoding granule cells (GCs) in the hippocampal dentate gyrus (DG). Young immature GCs (imGCs) appear through adult neurogenesis. In comparison to the mature GCs (mGCs) (born during development), the imGCs…

In this paper we explain the strikingly regular activity of the 'grid' cells in rodent dorsal medial entorhinal cortex (dMEC) and the spatially localized activity of the hippocampal place cells in CA3 and CA1 by assuming that the…

The hippocampus is an essential brain region for spatial memory and learning. Recently, a theoretical model of the hippocampus based on temporal difference (TD) learning has been published. Inspired by the successor representation (SR)…

The hippocampus is often attributed to episodic memory formation and storage in the mammalian brain; in particular, Alme et al. showed that hippocampal area CA3 forms statistically independent representations across a large number of…

The hippocampus has been associated with both spatial cognition and episodic memory formation, but integrating these functions into a unified framework remains challenging. Here, we demonstrate that forming discrete memories of visual…

The entorhinal-hippocampal formation is the mammalian brain's navigation system, encoding both physical and abstract spaces via grid cells. This system is well-studied in neuroscience, and its efficiency and versatility make it attractive…

Lattices abound in nature - from the crystal structure of minerals to the honey-comb organization of ommatidia in the compound eye of insects. Such regular arrangements provide solutions for optimally dense packings, efficient resource…

In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…

Place cells in the rat hippocampus play a key role in creating the animal's internal representation of the world. During active navigation, these cells spike only in discrete locations, together encoding a map of the environment.…

We present a computational model based on the CRISP theory (Content Representation, Intrinsic Sequences, and Pattern completion) of the hippocampus that allows to continuously store pattern sequences online in a one-shot fashion. Rather…

In the mammalian brain, newly acquired memories depend on the hippocampus for maintenance and recall, but over time the neocortex takes over these functions, rendering memories hippocampus-independent. The process responsible for this…

We propose HiCL, a novel hippocampal-inspired dual-memory continual learning architecture designed to mitigate catastrophic forgetting by using elements inspired by the hippocampal circuitry. Our system encodes inputs through a…