相关论文: The structure of human olfactory space

In this paper we propose the use of the Word2vec algorithm in order to obtain odor perception embeddings (or smell embeddings), only using publicly available perfume descriptions. Besides showing meaningful similarity relationships among…

Mitral cells, the principal neurons in the olfactory bulb, respond to odorants by firing bursts of action potentials called sharp events. A given cell produces a sharp event at a fixed phase during the sniff cycle in response to a given…

The application of large language models (LLMs) to OdorSpace analysis attracts growing interest. Recent studies have explored the comparison of sensory evaluation spaces derived from LLMs with odor character profiles in the Dravnieks'…

The sense of smell is an important part of living organisms. It assists with the interaction of the living organism with its environment. The mechanism by which smell is detected and identified is not fully known. Earlier, shape theory was…

Olfactory systems use a small number of broadly sensitive receptors to combinatorially encode a vast number of odors. We propose a method of decoding such distributed representations by exploiting a statistical fact: receptors that do not…

Real-world applications of computer vision in the humanities require algorithms to be robust against artistic abstraction, peripheral objects, and subtle differences between fine-grained target classes. Existing datasets provide…

Increasing attention has been recently devoted to protein-based nanobiosensors. The main reason is the huge number of possible technological applications, going from drug detection to cancer early diagnosis. Their operating model is based…

Local computation in microcircuits is an essential feature of distributed information processing in vertebrate and invertebrate brains. The insect antennal lobe represents a spatially confined local network that processes high-dimensional…

The olfactory system of male moths is exquisitely sensitive to pheromones emitted by females and transported in the environment by atmospheric turbulence. Moths respond to minute amounts of pheromones and their behavior is sensitive to the…

Odor sensory evaluation has a broad application in food, clothing, cosmetics, and other fields. Traditional artificial sensory evaluation has poor repeatability, and the machine olfaction represented by the electronic nose (E-nose) is…

While visual and auditory information conveyed by wavelength of light and frequency of sound have been decoded, predicting olfactory information encoded by the combination of odorants remains challenging due to the unknown and potentially…

We explore a suite of generative modelling techniques to efficiently navigate and explore the complex landscapes of odor and the broader chemical space. Unlike traditional approaches, we not only generate molecules but also predict the odor…

Olfactory receptor usage is highly heterogeneous, with some receptor types being orders of magnitude more abundant than others. We propose an explanation for this striking fact: the receptor distribution is tuned to maximally represent…

Odor detection underpins food safety, environmental monitoring, medical diagnostics, and many more fields. The current artificial sensors developed for odor detection struggle with complex mixtures while non-invasive recordings lack…

The olfactory system removes correlations in natural odors using a network of inhibitory neurons in the olfactory bulb. It has been proposed that this network integrates the response from all olfactory receptors and inhibits them equally.…

The validity of the dissipative quantum model of olfaction has not been examined yet and therefore the model suffers from the lack of experimental support. Here, we generalize the model and propose a numerical analysis of the dissipative…

Ligands for only two human olfactory receptors are known. One of them, OR1D2, binds to Bourgeonal [Malnic B, Godfrey P-A, Buck L-B (2004) The human olfactory receptor gene family. Proc. Natl. Acad. Sci U. S. A. 101: 2584-2589 and Erratum…

A recent Science paper (Bushdid et al, 2014)[1] proposed that humans can discriminate between at least a trillion olfactory stimuli. Here we show that this claim is the result of a fragile estimation framework capable of producing nearly…

Public olfaction datasets are small and fragmented across single molecules and mixtures, limiting learning of generalizable odor representations. Recent works either learn single-molecule embeddings or address mixtures via similarity or…

Animals use stereo sampling of odor concentration to localize sources and follow odor trails. We analyze the dynamics of a bilateral model that depends on the simultaneous comparison between odor concentrations detected by left and right…