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Simulation-based image quality metrics are adapted and investigated for characterizing the parameter dependences of linear iterative image reconstruction for DBT. Three metrics based on 2D DBT simulation are investigated: (1) a…

医学物理 · 物理学 2017-11-01 Sean D. Rose , Adrian A. Sanchez , Emil Y. Sidky , Xiaochuan Pan

Digital Breast Tomosynthesis (DBT) enhances finding visibility for breast cancer detection by providing volumetric information that reduces the impact of overlapping tissues; however, limited annotated data has constrained the development…

计算机视觉与模式识别 · 计算机科学 2025-11-14 Yen Nhi Truong Vu , Dan Guo , Sripad Joshi , Harshit Kumar , Jason Su , Thomas Paul Matthews

Reconstruction in limited-angle digital breast tomosynthesis (DBT) suffers from slow convergence of low spatial-frequency components when using weighted data-fidelity terms within primal-dual optimization. We introduce a two-channel…

最优化与控制 · 数学 2026-03-26 Taro Iyadomi , Ricardo Parada , Anna Kim , Lily Jiang , Emil Sidky , William Chang

X-ray computed tomographic infrastructures are medical imaging modalities that rely on the acquisition of rays crossing examined objects while measuring their intensity decrease. Physical measurements are post-processed by mathematical…

图像与视频处理 · 电气工程与系统科学 2022-01-25 Attila Juhos

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

图像与视频处理 · 电气工程与系统科学 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

Total variation (TV) regularization is a popular reconstruction method for ill-posed imaging problems, and particularly useful for applications with piecewise constant targets. However, using TV for medical cone-beam computed X-ray…

医学物理 · 物理学 2024-12-11 Alexander Meaney , Mikael A. K. Brix , Miika T. Nieminen , Samuli Siltanen

The reconstruction of images from measured data is an increasing field of research. For highly under-determined problems, template-based image reconstruction provides a way of compensating for the lack of sufficient data. A caveat of this…

最优化与控制 · 数学 2023-05-29 Sebastian Neumayer , Antonia Topalovic

Ultrasound computed tomography (USCT) is an emerging modality for breast imaging. Image reconstruction methods that incorporate accurate wave physics produce high resolution quantitative images of acoustic properties but are computationally…

图像与视频处理 · 电气工程与系统科学 2025-02-14 Luke Lozenski , Hanchen Wang , Fu Li , Mark A. Anastasio , Brendt Wohlberg , Youzuo Lin , Umberto Villa

The importance of regularization has been well established in image reconstruction -- which is the computational inversion of imaging forward model -- with applications including deconvolution for microscopy, tomographic reconstruction,…

图像与视频处理 · 电气工程与系统科学 2021-06-29 Sanjay Viswanath , Manu Ghulyani , Muthuvel Arigovindan

Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…

医学物理 · 物理学 2017-11-22 Wenxiang Cong , Xavier Intes , Ge Wang

Photon-counting computed tomography (PCCT) has emerged as a promising imaging technique, enabling spectral imaging and material decomposition (MD). However, images typically suffer from a low signal-to-noise ratio (SNR) due to constraints…

Although digital breast tomosynthesis (DBT) improves diagnostic performance over full-field digital mammography (FFDM), false-positive recalls remain a concern in breast cancer screening. We developed a multi-modal artificial intelligence…

图像与视频处理 · 电气工程与系统科学 2025-04-14 Jungkyu Park , Jan Witowski , Yanqi Xu , Hari Trivedi , Judy Gichoya , Beatrice Brown-Mulry , Malte Westerhoff , Linda Moy , Laura Heacock , Alana Lewin , Krzysztof J. Geras

Objective: In this work, we perform margin assessment of human breast tissue from optical coherence tomography (OCT) images using deep neural networks (DNNs). This work simulates an intraoperative setting for breast cancer lumpectomy.…

Inverse problems are fundamental in fields like medical imaging, geophysics, and computerized tomography, aiming to recover unknown quantities from observed data. However, these problems often lack stability due to noise and…

数值分析 · 数学 2024-06-26 Andrea Ebner , Matthias Schwab , Markus Haltmeier

Reconstruction of digital breast tomosynthesis is a challenging problem due to the limited angle data available in such systems. Due to memory limitations, deep learning-based methods can help improve these reconstructions, but can not…

医学物理 · 物理学 2020-09-04 Koen Michielsen , Nikita Moriakov , Jonas Teuwen , Ioannis Sechopoulos

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

医学物理 · 物理学 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

Low dose X-ray computed tomography (LDCT) is desirable for reduced patient dose. This work develops image reconstruction methods with deep learning (DL) regularization for LDCT. Our methods are based on unrolling of proximal…

图像与视频处理 · 电气工程与系统科学 2020-08-26 Qiaoqiao Ding , Gaoyu Chen , Xiaoqun Zhang , Qiu Huang , Hui Jiand Hao Gao

Purpose: Many useful image quality metrics for evaluating linear image reconstruction techniques do not apply to or are difficult to interpret for non-linear image reconstruction. The vast majority of metrics employed for evaluating…

One of the key impediments for developing and assessing robust medical imaging algorithms is limited access to large-scale datasets with suitable annotations. Synthetic data generated with plausible physical and biological constraints may…

计算机视觉与模式识别 · 计算机科学 2025-09-19 Christopher Wiedeman , Anastasiia Sarmakeeva , Elena Sizikova , Daniil Filienko , Miguel Lago , Jana G. Delfino , Aldo Badano

Statistical iterative reconstruction is expected to improve the image quality of megavoltage computed tomography (MVCT). However, one of the challenges of iterative reconstruction is its large computational cost. The purpose of this work is…