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One of the challenges in functional brain imaging is integration of complementary imaging modalities, such as magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI). MEG, which uses highly sensitive superconducting…

Magnetoencephalography (MEG) and magnetic resonance imaging at ultra-low fields (ULF MRI) are two methods based on the ability of SQUID (superconducting quantum interference device) sensors to detect femtotesla magnetic fields. Combination…

Parallel imaging techniques have been widely used in high-field magnetic resonance imaging (MRI). Multiple receiver coils have been shown to improve image quality and allow accelerated image acquisition. Magnetic resonance imaging at…

医学物理 · 物理学 2008-11-26 V. S. Zotev , P. L. Volegov , A. N. Matlashov , M. A. Espy , J. C. Mosher , R. H. Kraus

Magnetic resonance imaging at ultra-low fields (ULF MRI) is a promising new imaging method that uses SQUID sensors to measure the spatially encoded precession of pre-polarized nuclear spin populations at a microtesla-range measurement…

医学物理 · 物理学 2007-10-18 V. S. Zotev , A. N. Matlashov , P. L. Volegov , A. V. Urbaitis , M. A. Espy , R. H. Kraus

Superconducting QUantum-Interference Devices (SQUIDs) make magnetic resonance imaging (MRI) possible in ultra-low microtesla-range magnetic fields. In this work, we investigate the design parameters affecting the signal and noise…

仪器与探测器 · 物理学 2020-01-16 Koos C. J. Zevenhoven , Antti J. Mäkinen , Risto J. Ilmoniemi

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

医学物理 · 物理学 2019-12-02 Peng Cao , Jing Liu , Shuyu Tang , Andrew Leynes , Janine M. Lupo , Duan Xu , Peder E. Z. Larson

A seven-channel system capable of performing both magnetoencephalography (MEG) and ultra-low-field magnetic resonance imaging (ULF MRI) is described. The system consists of seven second-order SQUID gradiometers with 37 mm diameter and 60 mm…

Magnetoencephalography (MEG) enables the study of brain activity by recording the magnetic fields generated by neural currents and has become an important technique for neuroscientists in research and clinical settings. Unlike the…

Skull stripping magnetic resonance images (MRI) of the human brain is an important process in many image processing techniques, such as automatic segmentation of brain structures. Numerous methods have been developed to perform this task,…

图像与视频处理 · 电气工程与系统科学 2026-04-16 Hjalti Thrastarson , Lotta M. Ellingsen

Ultra-high resolution 7 tesla (7T) magnetic resonance imaging (MRI) provides detailed anatomical views, offering better signal-to-noise ratio, resolution and tissue contrast than 3T MRI, though at the cost of accessibility. We present an…

Here we present a multichannel system based on superconducting quantum interference devices (SQUIDs) for magnetoencephalography (MEG) measurements, developed and installed at Istituto di Cibernetica (ICIB) in Naples. This MEG system,…

医学物理 · 物理学 2013-10-18 S Rombetto , C Granata , A Vettoliere , A Trebeschi , R Rossi , M Russo

Joint modeling of diffusion and relaxation has seen growing interest due to its potential to provide complementary information about tissue microstructure. For brain white matter, we designed an optimal diffusion-relaxometry MRI protocol…

Magnetic resonance imaging (MRI) is the standard modality to understand human brain structure and function in vivo (antemortem). Decades of research in human neuroimaging has led to the widespread development of methods and tools to provide…

Ex vivo MRI of the brain provides remarkable advantages over in vivo MRI for visualizing and characterizing detailed neuroanatomy. However, automated cortical segmentation methods in ex vivo MRI are not well developed, primarily due to…

Quantitative magnetic resonance imaging might provide a more specific insight into disease process, progression and therapeutic response of multiple sclerosis. We present an extension of a previously published approach for the simultaneous…

Axon radius is a potential biomarker for brain diseases and a crucial tissue microstructure parameter that determines the speed of action potentials. Diffusion MRI (dMRI) allows non-invasive estimation of axon radius, but accurately…

Ultra-high field MRI offers unprecedented detail for non-invasive visualization of the human brain. However, brain imaging is challenging at 7T due to the B$_1^+$ field inhomogeneity, which results in signal intensity drops in temporal…

医学物理 · 物理学 2024-03-13 Vladislav Koloskov , Wyger Brink , Andrew Webb , Alena Shchelokova

We have developed a novel scanning probe-based methodology to study cell biomechanics. The time dependence of the force exerted by the cell surface on a scanning probe at constant local deformation has been used to extract local…

生物物理 · 物理学 2009-04-20 Susana Moreno-Flores , Rafael Benitez , Maria dM Vivanco , Jose Luis Toca-Herrera

Access to and availability of MRI scanners is typically limited by their cost, siting and infrastructure requirements. This precludes MRI diagnostics, the reference standard for neurological assessment, in patients who cannot be transported…

We report on precise measurements of magnetic field gradients extracted from transverse relaxation rates of precessing spin samples. The experimental approach is based on the free precession of gaseous, nuclear spin polarized $^3$He and…

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