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Research in blast-induced lung injury resulted in exposure thresholds that are useful in understanding and protecting humans from such injury. Because traumatic brain injury (TBI) due to blast exposure has become a prominent medical and…

医学物理 · 物理学 2011-02-09 Michael Courtney , Amy Courtney

The mechanisms by which blast pressure waves cause mild to moderate traumatic brain injury (mTBI) are an open question. Possibilities include acceleration of the head, direct passage of the blast wave via the cranium, and propagation of the…

医学物理 · 物理学 2008-12-31 Amy Courtney , Michael Courtney

Identifying patients at risk of traumatic brain injury (TBI) is important because research suggests prophylactic treatments to reduce risk of long-term sequelae. Blast pressure waves can cause TBI without penetrating wounds or blunt force…

医学物理 · 物理学 2008-08-12 Amy Courtney , Michael Courtney

The prediction and prevention of traumatic brain injury is a very important aspect of preventive medical science. This paper proposes a new coupled loading-rate hypothesis for the traumatic brain injury (TBI), which states that the main…

组织与器官 · 定量生物学 2008-11-18 Vladimir G. Ivancevic

The discovery that repetitive mild traumatic brain injury (mTBI) can result in chronic traumatic encephalopathy (CTE) in high risk contact sports has led to increased scrutiny of head protective gear. In this work, we asked if it was…

Impact induced traumatic brain injury (ITBI) describes brain injury from head impact not necessarily accompanied by skull fracture. For sufficiently abrupt head impact decelerations, ITBI results from brain tissue stress incurred as the…

医学物理 · 物理学 2009-04-21 Eric G. Blackman

Mild traumatic brain injury (mTBI, also known as concussion) caused by the head impact is a crucial global public health problem, but the physics of mTBI is still unclear. During the impact, the rapid movement of the head injures the brain,…

Repeated exposure to low-level blast may initiate a range of adverse health problem such as traumatic brain injury (TBI). Although many studies successfully identified genes associated with TBI, yet the cellular mechanisms underpinning TBI…

基因组学 · 定量生物学 2018-11-13 Akram Yazdani

The following study is motivated by experimental studies in traumatic brain injury (TBI). Recent research has demonstrated that low intensity non-impact blast wave exposure frequently leads to mild traumatic brain injury (mTBI); however,…

数值分析 · 数学 2018-04-24 Mauricio J. Del Razo , Randall J. LeVeque

Primary blast-induced traumatic brain injury (TBI) has increased in documented incidence and public prominence in recent conflicts. Evidence for a thoracic mechanism of blast-induced TBI was recently reviewed and, while the totality is…

医学物理 · 物理学 2011-05-25 Amy Courtney , Michael Courtney

Traumatic brain injury (TBI) occurs when local mechanical load exceeds certain tolerance levels for brain tissue. Extensive research has been done previously for brain matter experiencing compression at quasistatic loading; however, limited…

生物物理 · 物理学 2013-02-20 Badar Rashid , Michel Destrade , Michael Gilchrist

Traumatic brain injury (TBI) is caused by a sudden trauma to the head that may result in hematomas and contusions and can lead to stroke or chronic disability. An accurate quantification of the lesion volumes and their locations is…

计算机视觉与模式识别 · 计算机科学 2018-07-31 Snehashis Roy , John A. Butman , Leighton Chan , Dzung L. Pham

Brain injuries resulting from mechanical trauma represent an ongoing global public health issue. Several $\textit{in vitro}$ and $\textit{in vivo}$ models for traumatic brain injury (TBI) continue to be developed for delineating the various…

生物物理 · 物理学 2023-08-28 Yang Wan , Rafael D. González-Cruz , Diane Hoffman-Kim , Haneesh Kesari

Traumatic brain injury (TBI) can result in chronic sensorimotor, cognitive, psychosocial, and communication challenges that can limit social participation. Social media can be a useful outlet for social participation for individuals with…

人机交互 · 计算机科学 2023-04-05 Hajin Lim , Lisa Kakonge , Yaxin Hu , Lyn S. Turkstra , Melissa C. Duff , Catalina L. Toma , Bilge Mutlu

Nonlinear evolution of shear waves into shocks in incompressible elastic materials is investigated using the framework of large deformation elastodynamics, for a family of loadings and commonly used hyperelastic material models. Closed form…

软凝聚态物质 · 物理学 2019-07-17 Chockalingam Senthilnathan , Tal Cohen

With the evolution of modern warfare and the increased use of improvised explosive devices (IEDs), there has been an increase in blast-induced traumatic brain injuries (bTBI) among military personnel and civilians. The increased prevalence…

Traumatic brain injury (TBI) is a complex injury that is hard to predict and diagnose, with many studies focused on associating head kinematics to brain injury risk. Recently, there has been a push towards using computationally expensive…

The mechanical characterization of brain tissue at high loading velocities is vital for understanding and modeling Traumatic Brain Injury (TBI). The most severe form of TBI is diffuse axonal injury (DAI) which involves damage to individual…

生物物理 · 物理学 2013-02-19 Badar Rashid , Michel Destrade , Michael Gilchrist

Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

This paper presents a summary of seven distinct chains of evidence, which, taken together, provide compelling support for the theory that a ballistic pressure wave radiating outward from the penetrating projectile can contribute to wounding…

医学物理 · 物理学 2008-03-21 Michael Courtney , Amy Courtney
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