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Empirical evidence is presented which contradicts the established interpretation of the intraspecific genetic variability as the adaptive potential of the species: the uniform evolutionary tempo across the life kingdom, species…

种群与进化 · 定量生物学 2011-01-04 Anastassia M. Makarieva , Victor G. Gorshkov

The protein folding problem is stated and a list of properties that do not depend upon specific molecules is compiled and analyzed. The relationship of this analysis to future simulations is emphasized. The choice of power and time as…

生物物理 · 物理学 2017-09-26 Walter A. Simmons

The idea of possible time or space variations of the `fundamental' constants of nature, although not new, is only now beginning to be actively considered by large numbers of researchers in the particle physics, cosmology and astrophysics…

天体物理学 · 物理学 2009-11-07 C. J. A. P. Martins

We study mechanisms for wavenumber selection in a minimal model for run-and-tumble dynamics. We show that nonlinearity in tumbling rates induces the existence of a plethora of traveling- and standing-wave patterns, as well as a subtle…

斑图形成与孤子 · 物理学 2017-02-14 Arnd Scheel , Angela Stevens

The formation of DNA loops by proteins and protein complexes is ubiquitous to many fundamental cellular processes, including transcription, recombination, and replication. Here we review recent advances in understanding the properties of…

生物大分子 · 定量生物学 2007-05-23 Leonor Saiz , Jose M. G. Vilar

Language similarities can be caused by genetic relatedness, areal contact, universality, or chance. Colexification, i.e. a type of similarity where a single lexical form is used to convey multiple meanings, is underexplored. In our work, we…

计算与语言 · 计算机科学 2024-01-08 Yiyi Chen , Johannes Bjerva

The structure of the genetic code is discussed in formal terms. A rectangular table of the code ("the code matrix"), whose properties reveal its arithmetical content tagged with the information symbols in several notations. New parameters…

其他定量生物学 · 定量生物学 2009-07-22 Felix Filatov

The bare bones of a theory of quantum gravity are exposed. It may have the potential to solve the cosmological constant problem. Less certain is its behavior in the Newtonian limit.

高能物理 - 理论 · 物理学 2007-05-23 Paul Federbush

The systematics of indices of physico-chemical properties of codons and amino acids across the genetic code are examined. Using a simple numerical labelling scheme for nucleic acid bases, data can be fitted as low-order polynomials of the 6…

生物物理 · 物理学 2009-11-05 J. D. Bashford , P. D. Jarvis

How proteins fold remains a central unsolved problem in biology. While the idea of a folding code embedded in the amino acid sequence was introduced more than 6 decades ago, this code remains undefined. While we now have powerful predictive…

生物大分子 · 定量生物学 2025-11-04 Carlos Bustamante , Christian Kaiser , Erik Lindahl , Robert Sosa , Giovanni Volpe

While it is well-understood what a normal human placenta should look like, a deviation from the norm can take many possible shapes. In this paper we propose a mechanism for this variability based on the change in the structure of the…

组织与器官 · 定量生物学 2008-01-03 Michael Yampolsky , Carolyn M. Salafia , Oleksandr Shlakhter , Danielle Haas , Barbara Eucker , John Thorp

The aim of this note, which raises more questions than it answers, is to study natural operations acting on the cohomology of various types of algebras. It contains a lot of very surprising partial results and examples.

代数拓扑 · 数学 2007-05-23 Martin Markl

Due to a lack of coherent analysis, many common practices of humankind preserve low-efficient procedures. Balancing tubes during centrifugation exemplifies such a problem in laboratory practice. Using combination of symmetry group theory…

仪器与探测器 · 物理学 2010-04-22 Oleg Peil , Vasili Hauryliuk

This article is interested in the origin of the genetic code, it puts forward a scenario of a simultaneous selection of the bases and amino acids and setting up of a correlation between them. Each amino acid is associated with a pair of its…

生物大分子 · 定量生物学 2020-12-18 Pierre Zofel

Bristle-bots are legged robots that can be easily made out of a toothbrush head and a small vibrating engine. Despite their simple appearance, the mechanism enabling them to propel themselves by exploiting friction with the substrate is far…

混沌动力学 · 物理学 2017-02-02 Giancarlo Cicconofri , Antonio DeSimone

Gene expression has a stochastic component owing to the single molecule nature of the gene and the small number of copies of individual DNA binding proteins in the cell. We show how the statistics of such systems can be mapped on to quantum…

无序系统与神经网络 · 物理学 2009-11-10 Masaki Sasai , Peter G. Wolynes

This is a research announcement of the theory of orbifold quantum cohomology.

代数几何 · 数学 2007-05-23 Weimin Chen , Yongbin Ruan

There is no proof yet of convergence of Genetic Algorithms. We do not supply it too. Instead, we present some thoughts and arguments to convince the Reader, that Genetic Algorithms are essentially bound for success. For this purpose, we…

神经与进化计算 · 计算机科学 2007-05-23 Marek W. Gutowski

The main statistical distributions applicable to the analysis of genome architecture and genome tracks are briefly discussed and critically assessed. Although the observed features in distributions of element lengths can be equally well…

其他定量生物学 · 定量生物学 2015-06-17 V. R. Chechetkin

This article reports on simulations that show how, starting with a form of neural lattice structure, it is possible to reversibly generate many alternative isomers with a lower structural symmetry, which results from twisting two hexagons…

其他定量生物学 · 定量生物学 2016-11-09 Arturo Tozzi , James F. Peters , Ottorino Ori